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English
Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive.
scientific article published on 07 June 2013
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scholarly article
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stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
title
Young and old genetically heterogeneous HET3 mice on a rapamycin diet are glucose intolerant but insulin sensitive
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
main subject
glycobiology
0 references
glucose
0 references
preproinsulin
1 reference
based on heuristic
inferred from title
sirolimus
1 reference
based on heuristic
inferred from title
author
Dudley W Lamming
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Joseph A. Baur
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
David M. Sabatini
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
author name string
Lan Ye
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Clinton M Astle
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
David E Harrison
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
language of work or name
English
1 reference
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inferred from title
publication date
7 June 2013
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
published in
Aging Cell
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
volume
12
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
page(s)
712-718
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
cites work
Long-term p110α PI3K inactivation exerts a beneficial effect on metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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29 September 2017
Short-term treatment with rapamycin and dietary restriction have overlapping and distinctive effects in young mice
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PubMed Central
reference URL
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29 September 2017
Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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29 September 2017
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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29 September 2017
Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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29 September 2017
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
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PubMed Central
reference URL
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29 September 2017
Life extension by diet restriction and N-acetyl-L-cysteine in genetically heterogeneous mice
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29 September 2017
Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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29 September 2017
mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells
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PubMed Central
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29 September 2017
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
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PubMed Central
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29 September 2017
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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29 September 2017
Sirolimus is associated with new-onset diabetes in kidney transplant recipients.
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29 September 2017
mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex
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29 September 2017
Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice
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29 September 2017
Resveratrol improves health and survival of mice on a high-calorie diet
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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29 September 2017
Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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29 September 2017
Use and abuse of HOMA modeling
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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29 September 2017
Correct homeostasis model assessment (HOMA) evaluation uses the computer program
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29 September 2017
Surrogate measures of insulin resistance: of rats, mice, and men.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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4 September 2018
Glucose metabolism in renal transplant recipients: effect of calcineurin inhibitor withdrawal and conversion to sirolimus
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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4 September 2018
Economic costs of diabetes in the US in 2002.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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4 September 2018
Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-1 and IRS-2 in liver of Ames dwarf mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727050
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4 September 2018
Identifiers
DOI
10.1111/ACEL.12097
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Fatcat ID
release_5srxjrl2orbn7b4zx3yz5fzm7m
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/5srxjrl2orbn7b4zx3yz5fzm7m
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMC publication ID
3727050
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PubMed publication ID
23648089
1 reference
stated in
Europe PubMed Central
PMC publication ID
3727050
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23648089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
ResearchGate publication ID
236641886
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