(Q37055488)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

0 references

0 references

Manoel Arcisio-Miranda

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Baron Chanda

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Deborah L Capes

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Marcel P Goldschen-Ohm

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Francisco Bezanilla

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

publication date

15 July 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

The Journal of General Physiology

5 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

volume

142

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

page(s)

101-112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

Multiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channel

5 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Ion channel voltage sensors: structure, function, and pathophysiology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Sodium channelopathies of skeletal muscle result from gain or loss of function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Molecular determinants of coupling between the domain III voltage sensor and pore of a sodium channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

A single charged voltage sensor is capable of gating the Shaker K+ channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Deconstructing voltage sensor function and pharmacology in sodium channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Na channel inactivation from open and closed states

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Site-3 toxins and cardiac sodium channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

A quantitative description of membrane current and its application to conduction and excitation in nerve

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Voltage-sensor sodium channel mutations cause hypokalemic periodic paralysis type 2 by enhanced inactivation and reduced current

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

The role of the putative inactivation lid in sodium channel gating current immobilization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

The voltage sensor in voltage-dependent ion channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Movement of voltage sensor S4 in domain 4 is tightly coupled to sodium channel fast inactivation and gating charge immobilization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Augmentation of recovery from inactivation by site-3 Na channel toxins. A single-channel and whole-cell study of persistent currents

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Voltage-insensitive gating after charge-neutralizing mutations in the S4 segment of Shaker channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

The long QT syndrome: ion channel diseases of the heart

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Role in fast inactivation of the IV/S4-S5 loop of the human muscle Na+ channel probed by cysteine mutagenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Sodium channel inactivation is altered by substitution of voltage sensor positive charges

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Interaction between the sodium channel inactivation linker and domain III S4-S5.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

A unique role for the S4 segment of domain 4 in the inactivation of sodium channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Characterization of human cardiac Na+ channel mutations in the congenital long QT syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Sodium channel defects in myotonia and periodic paralysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Inactivation defects caused by myotonia-associated mutations in the sodium channel III-IV linker

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Cardiac sodium channel mutations in patients with long QT syndrome, an inherited cardiac arrhythmia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Statistical properties of single sodium channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Gating of Na channels. Inactivation modifiers discriminate among models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

A sodium channel gating model based on single channel, macroscopic ionic, and gating currents in the squid giant axon

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Voltage sensors in domains III and IV, but not I and II, are immobilized by Na+ channel fast inactivation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

A critical role for the S4-S5 intracellular loop in domain IV of the sodium channel alpha-subunit in fast inactivation

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Restoration of inactivation and block of open sodium channels by an inactivation gate peptide

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Inactivation of the sodium channel. II. Gating current experiments

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Phenotypic characterization of a novel long-QT syndrome mutation (R1623Q) in the cardiac sodium channel.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Na+ channels must deactivate to recover from inactivation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3727307

Evidence for voltage-dependent S4 movement in sodium channels

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23858005

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sodium channels need not open before they inactivate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23858005

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A reinterpretation of mammalian sodium channel gating based on single channel recording

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23858005

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1085/JGP.201310998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

23858005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23858005%20AND%20SRC:MED&resulttype=core&format=json