(Q37060045)

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Interactions between Human Cytomegalovirus IE1-72 and Cellular p107: Functional Domains and Mechanisms of Up-Regulation of Cyclin E/cdk2 Kinase Activity

scientific article published on December 1, 2003

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scholarly article

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Europe PubMed Central

18 August 2017

Interactions between human cytomegalovirus IE1-72 and cellular p107: functional domains and mechanisms of up-regulation of cyclin E/cdk2 kinase activity (English)

1 reference

Europe PubMed Central

18 August 2017

Interactions between Human Cytomegalovirus IE1-72 and Cellular p107: Functional Domains and Mechanisms of Up-Regulation of Cyclin E/cdk2 Kinase Activity (English)

1 reference

10.1128/JVI.77.23.12660-12670.2003

https://api.crossref.org/works/10.1128/JVI.77.23.12660-12670.2003

31 March 2024

Cytomegalovirus

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1 reference

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31 March 2024

positive regulation of biological process

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31 March 2024

1 reference

10.1128/JVI.77.23.12660-12670.2003

https://api.crossref.org/works/10.1128/JVI.77.23.12660-12670.2003

31 March 2024

1 reference

10.1128/JVI.77.23.12660-12670.2003

https://api.crossref.org/works/10.1128/JVI.77.23.12660-12670.2003

31 March 2024

author name string

Zhigang Zhang

1

1 reference

Europe PubMed Central

18 August 2017

Shu-Mei Huong

2

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Europe PubMed Central

18 August 2017

Xin Wang

3

1 reference

Europe PubMed Central

18 August 2017

Eng-Shang Huang

5

1 reference

Europe PubMed Central

18 August 2017

David Y. Huang

4

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Europe PubMed Central

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publication date

1 December 2003

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18 August 2017

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https://europepmc.org/articles/pmc262583?pdf=render

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31 March 2024

https://europepmc.org/articles/PMC262583

online access status

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Europe PubMed Central

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Europe PubMed Central

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31 March 2024

https://europepmc.org/articles/PMC262583?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610188

31 March 2024

https://doi.org/10.1128/jvi.77.23.12660-12670.2003

online access status

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14610188

31 March 2024

https://journals.asm.org/doi/pdf/10.1128/JVI.77.23.12660-12670.2003

1 reference

10.1128/JVI.77.23.12660-12670.2003

https://api.crossref.org/works/10.1128/JVI.77.23.12660-12670.2003

31 March 2024

Journal of Virology

1 reference

Europe PubMed Central

18 August 2017

77

1 reference

Europe PubMed Central

18 August 2017

23

1 reference

Europe PubMed Central

18 August 2017

12660-12670

1 reference

Europe PubMed Central

18 August 2017

G1 cyclin/cyclin-dependent kinase-coordinated phosphorylation of endogenous pocket proteins differentially regulates their interactions with E2F4 and E2F1 and gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Role of human cytomegalovirus immediate-early proteins in cell growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Dual cyclin-binding domains are required for p107 to function as a kinase inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

The cyclin E promoter is activated by human cytomegalovirus 86-kDa immediate early protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

The regulation of E2F by pRB-family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Cancer cell cycles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

The human cytomegalovirus IE1-72 protein interacts with the cellular p107 protein and relieves p107-mediated transcriptional repression of an E2F-responsive promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Retinoblastoma protein family in cell cycle and cancer: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Introduction to the E2F family: protein structure and gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Transcriptional activation by the human cytomegalovirus immediate-early proteins: requirements for simple promoter structures and interactions with multiple components of the transcription complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

CCAAT box-dependent activation of the TATA-less human DNA polymerase alpha promoter by the human cytomegalovirus 72-kilodalton major immediate-early protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

The retinoblastoma tumor suppressor protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

The Rb-related p107 protein can suppress E2F function independently of binding to cyclin A/cdk2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

The pRB-related protein p107 contains two growth suppression domains: independent interactions with E2F and cyclin/cdk complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

The retinoblastoma protein and cell cycle control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Interaction of the 72-kilodalton human cytomegalovirus IE1 gene product with E2F1 coincides with E2F-dependent activation of dihydrofolate reductase transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

1 reference

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29 September 2017

Identification and characterization of the human cytomegalovirus immediate-early region 2 gene that stimulates gene expression from an inducible promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Two specific topoisomerase II inhibitors prevent replication of human cytomegalovirus DNA: an implied role in replication of the viral genome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Human cytomegalovirus induces expression of cellular topoisomerase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

E2F mediates dihydrofolate reductase promoter activation and multiprotein complex formation in human cytomegalovirus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

Human cytomegalovirus. IV. Specific inhibition of virus-induced DNA polymerase activity and viral DNA replication by phosphonoacetic acid

1 reference

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29 September 2017

Stimulation of Cellular Thymidine Kinases by Human Cytomegalovirus

1 reference

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29 September 2017

The retinoblastoma gene product negatively regulates transcriptional activation mediated by the human cytomegalovirus IE2 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

29 September 2017

The adenovirus EIIA enhancer. Analysis of regulatory sequences and changes in binding activity of ATF and EIIF following adenovirus infection

1 reference

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27 June 2018

Identification of a growth suppression domain within the retinoblastoma gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

27 June 2018

The immediate early genes of human cytomegalovirus upregulate expression of the cellular genes myc and fos

1 reference

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27 June 2018

Herpes simplex virus type 1 infection imposes a G(1)/S block in asynchronously growing cells and prevents G(1) entry in quiescent cells

1 reference

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4 September 2018

In vivo and in vitro analysis of transcriptional activation mediated by the human cytomegalovirus major immediate-early proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262583

4 September 2018

A flavonoid antioxidant, silymarin, inhibits activation of erbB1 signaling and induces cyclin-dependent kinase inhibitors, G1 arrest, and anticarcinogenic effects in human prostate carcinoma DU145 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14610188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The immediate early gene products of human cytomegalovirus increase vascular smooth muscle cell migration, proliferation, and expression of PDGF beta-receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/14610188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Domain mapping of the human cytomegalovirus IE1-72 and cellular p107 protein-protein interaction and the possible functional consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/14610188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional control of the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/14610188

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochimica et Biophysica Acta

1

1287

103

publication date

1996

1 reference

10.1128/JVI.77.23.12660-12670.2003

https://api.crossref.org/works/10.1128/JVI.77.23.12660-12670.2003

31 March 2024

Retinoblastoma protein family in cell cycle and cancer: A review

29

1 reference

10.1128/JVI.77.23.12660-12670.2003

https://api.crossref.org/works/10.1128/JVI.77.23.12660-12670.2003

31 March 2024

Cancer Research

49

58

1920

publication date

1998

1 reference

10.1128/JVI.77.23.12660-12670.2003

https://api.crossref.org/works/10.1128/JVI.77.23.12660-12670.2003

31 March 2024

Identifiers

10.1128/JVI.77.23.12660-12670.2003

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

ResearchGate publication ID

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