(Q37074082)

18 August 2017

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title

Application of metabonomics in drug development (English)

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18 August 2017

Hector C Keun

1

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18 August 2017

Toby J Athersuch

series ordinal

2

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18 August 2017

publication date

1 July 2007

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18 August 2017

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18 August 2017

volume

8

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18 August 2017

issue

7

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18 August 2017

page(s)

731-741

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'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

18 August 2017

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21 January 2018

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Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models

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High-resolution (1)H NMR and magic angle spinning NMR spectroscopic investigation of the biochemical effects of 2-bromoethanamine in intact renal and hepatic tissue

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Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption

21 January 2018

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Pharmaco-metabonomic phenotyping and personalized drug treatment

21 January 2018

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Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia

21 January 2018

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Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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New modes of data partitioning based on PARS peak alignment for improved multivariate biomarker/biopattern detection in (1)H-NMR spectroscopic metabolic profiling of urine.

21 January 2018

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Scaling and normalization effects in NMR spectroscopic metabonomic data sets

21 January 2018

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Negative impact of noise on the principal component analysis of NMR data

21 January 2018

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Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets

21 January 2018

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Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies

21 January 2018

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Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Analytical reproducibility in (1)H NMR-based metabonomic urinalysis

21 January 2018

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Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

21 January 2018

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21 January 2018

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Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

21 January 2018

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Detection ofin vivo biomarkers of phospholipidosis using NMR-based metabonomic approaches

21 January 2018

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Nuclear Magnetic Resonance Spectroscopic and Principal Components Analysis Investigations into Biochemical Effects of Three Model Hepatotoxins

21 January 2018

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Susceptibility of Human Metabolic Phenotypes to Dietary Modulation

21 January 2018

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Improved analysis of multivariate data by variable stability scaling: application to NMR-based metabolic profiling

21 January 2018

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Systems Toxicology: Integrated Genomic, Proteomic and Metabonomic Analysis of Methapyrilene Induced Hepatotoxicity in the Rat

21 January 2018

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21 January 2018

Identifiers

DOI

10.2217/14622416.8.7.731

1 reference

18 August 2017

1 reference