(Q37084506)

18 August 2017

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title

Immunology of asthma and chronic obstructive pulmonary disease (English)

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chronic obstructive pulmonary disease

18 August 2017

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immunology

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author name string

Peter J Barnes

series ordinal

1

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PubMed ID

18274560

18 August 2017

language of work or name

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15 February 2008

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Nature Reviews Immunology

18 August 2017

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18 August 2017

8

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18 August 2017

3

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18 August 2017

183-192

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Chronic obstructive pulmonary disease: a growing but neglected global epidemic

18 August 2017

1 reference

Global burden of COPD: risk factors, prevalence, and future trends

31 March 2020

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Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC)

31 March 2020

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Asthma and chronic obstructive pulmonary disease exhibit common origins in any country!

31 March 2020

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Against the Dutch hypothesis: asthma and chronic obstructive pulmonary disease are distinct diseases.

31 March 2020

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Mechanisms in COPD: differences from asthma

31 March 2020

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Comparison of the structural and inflammatory features of COPD and asthma. Giles F. Filley Lecture.

31 March 2020

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Asthma: defining of the persistent adult phenotypes

31 March 2020

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The Melbourne Asthma Study: 1964-1999.

31 March 2020

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Mediators of chronic obstructive pulmonary disease

31 March 2020

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Activation and localization of transcription factor, nuclear factor-kappaB, in asthma

31 March 2020

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Nuclear localisation of p65 in sputum macrophages but not in sputum neutrophils during COPD exacerbations.

31 March 2020

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Airway structural alterations selectively associated with severe asthma.

31 March 2020

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Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis

31 March 2020

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Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression

31 March 2020

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Pathophysiology of airflow limitation in chronic obstructive pulmonary disease

31 March 2020

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The nature of small-airway obstruction in chronic obstructive pulmonary disease

31 March 2020

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Mucin expression in peripheral airways of patients with chronic obstructive pulmonary disease.

31 March 2020

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Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema

31 March 2020

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Is alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease?

31 March 2020

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State of the art. Cellular and molecular mechanisms of alveolar destruction in emphysema: an evolutionary perspective

31 March 2020

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Stem cell factor and its receptor c-Kit as targets for inflammatory diseases

31 March 2020

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Mast cells as "tunable" effector and immunoregulatory cells: recent advances.

31 March 2020

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Mast-cell infiltration of airway smooth muscle in asthma.

31 March 2020

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Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.

31 March 2020

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A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthma.

31 March 2020

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Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids

31 March 2020

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Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma

31 March 2020

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Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2.

31 March 2020

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Alveolar macrophages as orchestrators of COPD.

31 March 2020

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T cells and NKT cells in the pathogenesis of asthma

31 March 2020

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The role of T lymphocytes in asthma

31 March 2020

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Role of GATA-3 in allergic diseases

31 March 2020

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Expression of GATA family of transcription factors in T-cells, monocytes and bronchial biopsies

31 March 2020

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Gene expression of the GATA-3 transcription factor is increased in atopic asthma

31 March 2020

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Regulation of Th2 cytokine genes by p38 MAPK-mediated phosphorylation of GATA-3.

31 March 2020

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Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet

31 March 2020

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T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3.

31 March 2020

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IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation

31 March 2020

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T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

31 March 2020

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T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes.

31 March 2020

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IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo

31 March 2020

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IL-33 is a chemoattractant for human Th2 cells.

31 March 2020

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An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema

31 March 2020

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Increased expression of the chemokine receptor CXCR3 and its ligand CXCL10 in peripheral airways of smokers with chronic obstructive pulmonary disease.

31 March 2020

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CXCR3 and CCR5 Chemokines in Induced Sputum From Patients With COPD

31 March 2020

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Cytokine production by bronchoalveolar lavage T lymphocytes in chronic obstructive pulmonary disease

31 March 2020

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Asthma severity is associated with an increase in both blood CXCR3+ and CCR4+ T cells.

31 March 2020

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Regulatory T cells in allergy and asthma.

31 March 2020

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Relation of CD4+CD25+ regulatory T-cell suppression of allergen-driven T-cell activation to atopic status and expression of allergic disease.

31 March 2020

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The levels of CD4+CD25+ regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma

31 March 2020

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CD4-Regulatory Cells in COPD Patients

31 March 2020

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Regulatory T cells, transforming growth factor-beta, and immune suppression

31 March 2020

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Differentiation and function of Th17 T cells

31 March 2020

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Th17: an effector CD4 T cell lineage with regulatory T cell ties

31 March 2020

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IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx?

31 March 2020

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IL-17-induced cytokine release in human bronchial epithelial cells in vitro: role of mitogen-activated protein (MAP) kinases

31 March 2020

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Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

31 March 2020

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Interleukin-21: Basic Biology and Implications for Cancer and Autoimmunity

31 March 2020

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Interleukin-22: a novel T- and NK-cell derived cytokine that regulates the biology of tissue cells

31 March 2020

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CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma.

31 March 2020

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Invariant natural killer T cells in asthma and chronic obstructive pulmonary disease.

31 March 2020

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CD8+ T-lymphocytes in peripheral airways of smokers with chronic obstructive pulmonary disease

31 March 2020

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CCR3 functional responses are regulated by both CXCR3 and its ligands CXCL9, CXCL10 and CXCL11

31 March 2020

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Perforin expression and cytotoxic activity of sputum CD8+ lymphocytes in patients with COPD

31 March 2020

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Bronchial CD8 cell infiltrate and lung function decline in asthma.

31 March 2020

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Increased interleukin-4, interleukin-5, and interferon-gamma in airway CD4+ and CD8+ T cells in atopic asthma

31 March 2020

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IgE isotype determination: epsilon-germline gene transcription, DNA recombination and B-cell differentiation

31 March 2020

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Does anti-IgE therapy help in asthma? Efficacy and controversies

31 March 2020

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Class switch recombination to IgE in the bronchial mucosa of atopic and nonatopic patients with asthma

31 March 2020

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Hypothesis: does COPD have an autoimmune component?

31 March 2020

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Oligoclonal CD4+ T cells in the lungs of patients with severe emphysema

31 March 2020

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Antielastin autoimmunity in tobacco smoking-induced emphysema

31 March 2020

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Recent progress in the biology of airway dendritic cells and implications for understanding the regulation of asthmatic inflammation

31 March 2020

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Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity

31 March 2020

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Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells

31 March 2020

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Thymic stromal lymphopoietin: master switch for allergic inflammation

31 March 2020

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Cigarette smoking-induced changes in the number and differentiated state of pulmonary dendritic cells/Langerhans cells.

31 March 2020

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Bronchial mucosal dendritic cells in smokers and ex-smokers with COPD: an electron microscopic study

31 March 2020

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Severe asthma: lessons from the Severe Asthma Research Program

31 March 2020

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Neutrophilic inflammation in severe persistent asthma

31 March 2020

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Asthma and cigarette smoking.

31 March 2020

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Partial reversibility of airflow limitation and increased exhaled NO and sputum eosinophilia in chronic obstructive pulmonary disease

31 March 2020

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Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease.

31 March 2020

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Asthma exacerbations . 3: Pathogenesis.

31 March 2020

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Exacerbations of chronic obstructive pulmonary disease

31 March 2020

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Pathophysiology of exacerbations of chronic obstructive pulmonary disease

31 March 2020

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How corticosteroids control inflammation: Quintiles Prize Lecture 2005

31 March 2020

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Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

31 March 2020

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Reduced histone deacetylase in COPD: clinical implications

31 March 2020

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Corticosteroid resistance in chronic obstructive pulmonary disease: inactivation of histone deacetylase.

31 March 2020

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Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma

31 March 2020

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Relative corticosteroid insensitivity of peripheral blood mononuclear cells in severe asthma

31 March 2020

1 reference

Theophylline: new perspectives for an old drug

31 March 2020

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Allergen immunotherapy: present and future

31 March 2020

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Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study. Tokyo Joshi-Idai Asthma Research Group

31 March 2020

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B-cell targeting in rheumatoid arthritis and other autoimmune diseases

31 March 2020

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31 March 2020

New therapies for asthma

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Prospects for new drugs for chronic obstructive pulmonary disease

31 March 2020

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Transcription factors in airway diseases

31 March 2020

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Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice.

31 March 2020

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A closer look at chemokines and their role in asthmatic responses.

31 March 2020

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Chemokine receptors as therapeutic targets in chronic obstructive pulmonary disease.

31 March 2020

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Airway eosinophilia and expression of interleukin-5 protein in asthma and in exacerbations of chronic bronchitis

31 March 2020

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Exacerbations of Bronchitis: bronchial eosinophilia and gene expression for interleukin-4, interleukin-5, and eosinophil chemoattractants.

31 March 2020

1 reference

Airway mucosal inflammation in COPD is similar in smokers and ex-smokers: a pooled analysis

31 March 2020

1 reference

Amplification of inflammation in emphysema and its association with latent adenoviral infection

31 March 2020

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The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences

31 March 2020

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Rapid dendritic cell recruitment to the bronchial mucosa of patients with atopic asthma in response to local allergen challenge

31 March 2020

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Chemokines and their receptors in chronic pulmonary disease

31 March 2020

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31 March 2020

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Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients

31 March 2020

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Elevation of exhaled ethane concentration in asthma.

31 March 2020

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Exhaled 8-isoprostane as an in vivo biomarker of lung oxidative stress in patients with COPD and healthy smokers

31 March 2020

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Oxidant and antioxidant balance in the airways and airway diseases

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI2254

1 reference

18 August 2017

1 reference

PubMed ID

18274560