(Q37084859)

18 August 2017

1 reference

title

The Yin-Yang of thrombin and activated protein C. (English)

1 reference

18 August 2017

Tina Dutt

1

1 reference

18 August 2017

Cheng Hock Toh

series ordinal

2

1 reference

18 August 2017

language of work or name

English

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publication date

1 March 2008

1 reference

British Journal of Haematology

18 August 2017

published in

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18 August 2017

volume

140

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18 August 2017

issue

5

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18 August 2017

page(s)

505-515

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Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial

18 August 2017

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Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity

21 January 2018

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Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells

21 January 2018

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Identification of a thrombin sequence with growth factor activity on macrophages

21 January 2018

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Efficacy and safety of recombinant human activated protein C for severe sepsis

21 January 2018

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Mutation in blood coagulation factor V associated with resistance to activated protein C.

21 January 2018

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Platelet procoagulant activity: physiological significance and mechanisms of exposure

21 January 2018

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Fibrinogen and fibrin--proteins with complex roles in hemostasis and thrombosis

21 January 2018

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Structure and function of sphingolipid- and cholesterol-rich membrane rafts

21 January 2018

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Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

21 January 2018

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Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage

21 January 2018

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Tumor necrosis factor suppresses transcription of the thrombomodulin gene in endothelial cells

21 January 2018

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Thrombin signalling and protease-activated receptors

21 January 2018

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Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein C

21 January 2018

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450 million years of hemostasis.

21 January 2018

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The coagulation cascade: initiation, maintenance, and regulation

21 January 2018

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Plasma glucosylceramide deficiency as potential risk factor for venous thrombosis and modulator of anticoagulant protein C pathway

21 January 2018

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High-density lipoprotein deficiency and dyslipoproteinemia associated with venous thrombosis in men.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Decreased plasma sensitivity to activated protein C by oral contraceptives is associated with decreases in plasma glucosylceramide

21 January 2018

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Hepatic response to sepsis: interaction between coagulation and inflammatory processes.

21 January 2018

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Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation.

21 January 2018

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21 January 2018

The Protein C Pathway

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The interactions between inflammation and coagulation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Expression of endothelial protein C receptor and thrombomodulin in the intestinal tissue of patients with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Kinetics of the reaction of thrombin and alpha 2-macroglobulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Endothelial protein C receptor-dependent inhibition of human eosinophil chemotaxis by protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Endothelial protein C receptor-dependent inhibition of migration of human lymphocytes by protein C involves epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Cardiolipin enhances protein C pathway anticoagulant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR). The structural and functional conservation in human, bovine, and murine EPCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Activation mechanism of anticoagulant protein C in large blood vessels involving the endothelial cell protein C receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Characterization of protein C receptor expression in monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Autoantibodies against EPCR are found in antiphospholipid syndrome and are a risk factor for fetal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Protease-activated receptor 3 is a second thrombin receptor in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Anticoagulant properties of bovine plasma protein C following activation by thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

The soluble endothelial protein C receptor binds to activated neutrophils: involvement of proteinase-3 and CD11b/CD18

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Human protein C receptor is present primarily on endothelium of large blood vessels: implications for the control of the protein C pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Factor V Leiden: a clinical review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Exposure of platelet membrane phosphatidylserine regulates blood coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

PAR1 cleavage and signaling in response to activated protein C and thrombin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

What is all that thrombin for?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Thrombin and Phenotypic Modulation of the Endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Inherited thrombophilia in arterial disease: a selective review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Autoantibodies against the endothelial receptor of protein C are associated with acute myocardial infarction in young women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

The cytoprotective protein C pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Plasma lipoproteins support prothrombinase and other procoagulant enzymatic complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: role of protein kinases, calcium, and RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

The crystal structure of the endothelial protein C receptor and a bound phospholipid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Role of activated protein C in Helicobacter pylori-associated gastritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Activated protein C induces the release of microparticle-associated endothelial protein C receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Factor V Leiden mutation and the risks for thromboembolic disease: a clinical perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Glycolipid antigen processing for presentation by CD1d molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Regulated endothelial protein C receptor shedding is mediated by tumor necrosis factor-alpha converting enzyme/ADAM17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Low-dose oral contraceptives and acquired resistance to activated protein C: a randomised cross-over study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Thrombin-induced endothelial microparticle generation: identification of a novel pathway involving ROCK-II activation by caspase-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Anti-inflammatory, antithrombotic, and neuroprotective effects of activated protein C in a murine model of focal ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Functional rafts in cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Plasma levels of endothelial protein C receptor respond to anticoagulant treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Expression and function of the endothelial protein C receptor in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Activated protein C in sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Endothelial cell protein C receptor plays an important role in protein C activation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Preparation and properties of bovine factor VIII (antihemophilic factor).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Metalloproteolytic release of endothelial cell protein C receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Endothelial protein C receptor is overexpressed in rheumatoid arthritic (RA) synovium and mediates the anti-inflammatory effects of activated protein C in RA monocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Low levels of protein C are associated with poor outcome in severe sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Glucosylceramide, a neutral glycosphingolipid anticoagulant cofactor, enhances the interaction of human- and bovine-activated protein C with negatively charged phospholipid vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Predictive value of D-dimer test for recurrent venous thromboembolism after anticoagulation withdrawal in subjects with a previous idiopathic event and in carriers of congenital thrombophilia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

A new model to describe extrinsic protein binding to phospholipid membranes of varying composition: application to human coagulation proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

Actions of Thrombin and Other Coagulant and Proteolytic Enzymes on Blood Platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2007.06977.X

10.1111/J.1365-2141.2007.06977.X

21 January 2018

Identifiers

DOI

1 reference

release_a3zfbvdxdjc63dfcczj2tjuxi4

18 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/a3zfbvdxdjc63dfcczj2tjuxi4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference