(Q37088014)

18 August 2017

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title

The Na/K-ATPase/Src complex and cardiotonic steroid-activated protein kinase cascades (English)

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18 August 2017

Zhichuan Li

1

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18 August 2017

Zijian Xie

series ordinal

2

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18 August 2017

publication date

19 February 2008

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18 August 2017

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18 August 2017

volume

457

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18 August 2017

issue

3

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18 August 2017

page(s)

635-644

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https://scigraph.springernature.com/pub.10.1007/s00424-008-0470-0

18 August 2017

exact match

0 references

cites work

RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0470-0

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0470-0

Discrepancy between the short and long term effects of ouabain on the sodium pumps of human cells grown in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0470-0

Recent insights into the structure and mechanism of the sodium pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0470-0

Angiotensin II stimulates secretion of endogenous ouabain from bovine adrenocortical cells via angiotensin type 2 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0470-0

Effects of ouabain on proliferation, intracellular free calcium and c-myc mRNA expression in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0470-0

Role of caveolae in signal-transducing function of cardiac Na+/K+-ATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0470-0

Isozymes of the Na+/K+-ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00424-008-0470-0

Crystal structure of the Src family tyrosine kinase Hck

21 January 2018

1 reference

12 December 2020

Src tyrosine kinase is a novel direct effector of G proteins.

1 reference

12 December 2020

Functional characterization of Src-interacting Na/K-ATPase using RNA interference assay

1 reference

12 December 2020

Identification and characterization of a ouabain-like compound from human plasma

1 reference

12 December 2020

Partial inhibition of Na+/K+-ATPase by ouabain induces the Ca2+-dependent expressions of early-response genes in cardiac myocytes.

1 reference

12 December 2020

Inositol 1,4,5-trisphosphate receptors as signal integrators

1 reference

12 December 2020

Involvement of Src and epidermal growth factor receptor in the signal-transducing function of Na+/K+-ATPase

1 reference

12 December 2020

The influence of SRC-family tyrosine kinases on Na,K-ATPase activity in lens epithelium

1 reference

12 December 2020

Relationship between Na(+),K(+)-ATPase and cell attachment

1 reference

12 December 2020

A band 3-based macrocomplex of integral and peripheral proteins in the RBC membrane

1 reference

12 December 2020

Low doses of ouabain protect from serum deprivation-triggered apoptosis and stimulate kidney cell proliferation via activation of NF-kappaB

1 reference

12 December 2020

Na+, K+-ATPase in HeLa cells after prolonged growth in low K+ or ouabain

1 reference

12 December 2020

The alpha1 subunit of the sodium pump could represent a novel target to combat non-small cell lung cancers

1 reference

12 December 2020

Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors

1 reference

12 December 2020

Ouabain induces cell proliferation through calcium-dependent phosphorylation of Akt (protein kinase B) in opossum kidney proximal tubule cells.

1 reference

12 December 2020

Organ hypertrophic signaling within caveolae membrane subdomains triggered by ouabain and antagonized by PST 2238.

1 reference

12 December 2020

Biochemistry of Na,K-ATPase

1 reference

12 December 2020

Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes

1 reference

12 December 2020

Structure of the ankyrin-binding domain of alpha-Na,K-ATPase

1 reference

12 December 2020

The early effects of ouabain on potassium metabolism and rate of proliferation of mouse lymphoblasts

1 reference

12 December 2020

Interaction of the alpha subunit of Na,K-ATPase with cofilin

1 reference

12 December 2020

Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.

1 reference

12 December 2020

Basolateral Na+ pump modulates apical Na+ and K+ conductances in rabbit cortical collecting ducts

1 reference

12 December 2020

Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution

1 reference

12 December 2020

Membrane enzyme systems responsible for the Ca(2+)-dependent phosphorylation of Ser(27), the independent phosphorylation of Tyr(10) and Tyr(7), and the dephosphorylation of these phosphorylated residues in the alpha-chain of H/K-ATPase

1 reference

12 December 2020

The active site structure of Na+- and K+-stimulated ATPase. Location of a specific fluorescein isothiocyanate reactive site

1 reference

12 December 2020

Digitoxin inhibits the growth of cancer cell lines at concentrations commonly found in cardiac patients

1 reference

12 December 2020

Ouabain stimulates protein kinase B (Akt) phosphorylation in opossum kidney proximal tubule cells through an ERK-dependent pathway

1 reference

12 December 2020

[Ouabain binding and the conformational change in Na+, K+ -ATPase]

1 reference

12 December 2020

Jaks and Stats in signaling by the cytokine receptor superfamily

1 reference

12 December 2020

ATP-induced conformational changes of the nucleotide-binding domain of Na,K-ATPase

1 reference

12 December 2020

Three-dimensional structure of the tyrosine kinase c-Src

1 reference

12 December 2020

Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function.

1 reference

12 December 2020

Proteomics analysis of the proliferative effect of low-dose ouabain on human endothelial cells

1 reference

12 December 2020

Digitalis-induced signaling by Na+/K+-ATPase in human breast cancer cells.

1 reference

12 December 2020

The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na+-Ca2+ exchanger function

1 reference

12 December 2020

Ouabain-induced hypertrophy in cultured cardiac myocytes is accompanied by changes in expression of several late response genes

1 reference

12 December 2020

Structural changes in the calcium pump accompanying the dissociation of calcium

1 reference

12 December 2020

1 reference

12 December 2020

Multiple signal transduction pathways link Na+/K+-ATPase to growth-related genes in cardiac myocytes. The roles of Ras and mitogen-activated protein kinases

1 reference

12 December 2020

Ouabain assembles signaling cascades through the caveolar Na+/K+-ATPase

1 reference

12 December 2020

A tyrosine-specific protein kinase from Ehrlich ascites tumor cells

1 reference

12 December 2020

Ouabain enhances the mitogenic effect of serum in vascular smooth muscle cells

1 reference

12 December 2020

Membrane cation transport and the control of proliferation of mammalian cells

1 reference

12 December 2020

Identification of a transformation-specific antigen induced by an avian sarcoma virus

1 reference

12 December 2020

Identification of a binding motif for ankyrin on the alpha-subunit of Na+,K(+)-ATPase

1 reference

12 December 2020

HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction

1 reference

12 December 2020

A role for the Na/K-ATPase in the control of human c-fos and c-jun transcription

1 reference

12 December 2020

The Na+-Ca2+ exchanger is essential for the action of cardiac glycosides

1 reference

12 December 2020

Cardiac glycosides stimulate Ca2+ increases and apoptosis in androgen-independent, metastatic human prostate adenocarcinoma cells

1 reference

12 December 2020

Mechanism of apical K+ channel modulation in principal renal tubule cells. Effect of inhibition of basolateral Na(+)-K(+)-ATPase

1 reference

12 December 2020

Ouabain protects rat hearts against ischemia-reperfusion injury via pathway involving src kinase, mitoKATP, and ROS

1 reference

12 December 2020

Dual effects of ouabain on the regulation of proliferation and apoptosis in human prostatic smooth muscle cells

1 reference

12 December 2020

Central role for the cardiotonic steroid marinobufagenin in the pathogenesis of experimental uremic cardiomyopathy

1 reference

12 December 2020

Cellular functions regulated by Src family kinases

1 reference

12 December 2020

Phosphorylation of Na,K-ATPase by protein kinases. Sites, susceptibility, and consequences

1 reference

12 December 2020

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

12 December 2020

Recent developments in lymphocyte activation: linking kinases to downstream signaling events

1 reference

12 December 2020

Low-dose ouabain protects against excitotoxic apoptosis and up-regulates nuclear Bcl-2 in vivo

1 reference

12 December 2020

Inhibition of DNA topoisomerases I and II, and growth inhibition of breast cancer MCF-7 cells by ouabain, digoxin and proscillaridin A.

1 reference

12 December 2020

IRBIT, a novel inositol 1,4,5-trisphosphate (IP3) receptor-binding protein, is released from the IP3 receptor upon IP3 binding to the receptor

1 reference

12 December 2020

GPCRs signaling directly through Src-family kinases

1 reference

12 December 2020

Crystal structure of the sodium–potassium pump

1 reference

12 December 2020

Structure and mechanism of Na,K-ATPase: functional sites and their interactions

1 reference

12 December 2020

The influence of some cations on an adenosine triphosphatase from peripheral nerves

1 reference

12 December 2020

Dissecting independent channel and scaffolding roles of the Drosophila transient receptor potential channel

1 reference

12 December 2020

Organization of P-type ATPases: significance of structural diversity

1 reference

12 December 2020

Src-mediated inter-receptor cross-talk between the Na+/K+-ATPase and the epidermal growth factor receptor relays the signal from ouabain to mitogen-activated protein kinases

1 reference

12 December 2020

Regulation of c-SRC activity and function by the adapter protein CAS

1 reference

12 December 2020

Tiam1 is involved in the regulation of bufalin-induced apoptosis in human leukemia cells

1 reference

12 December 2020

Cross-talk and the role of KATP channels in the proximal tubule

1 reference

12 December 2020

Ouabain-induced signaling and vascular smooth muscle cell proliferation.

1 reference

12 December 2020

Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

1 reference

12 December 2020

Ouabain binds with high affinity to the Na,K-ATPase in human polycystic kidney cells and induces extracellular signal-regulated kinase activation and cell proliferation

1 reference

12 December 2020

Polycystins: polymodal receptor/ion-channel cellular sensors

1 reference

12 December 2020

Protein tyrosine kinase is expressed and regulates ROMK1 location in the cortical collecting duct

1 reference

12 December 2020

Proliferation and apoptosis of HeLa cells induced by in vitro stimulation with digitalis

1 reference

12 December 2020

The influence of Lyn kinase on Na,K-ATPase in porcine lens epithelium

1 reference

12 December 2020

Inhibition of the activity of SRC and Abl tyrosine protein kinases by the binding of the Wiskott-Aldrich syndrome protein

1 reference

12 December 2020

Ouabain induces endocytosis of plasmalemmal Na/K-ATPase in LLC-PK1 cells by a clathrin-dependent mechanism

1 reference

12 December 2020

Na/K-ATPase tethers phospholipase C and IP3 receptor into a calcium-regulatory complex

1 reference

12 December 2020

Association of PI3K-Akt signaling pathway with digitalis-induced hypertrophy of cardiac myocytes

1 reference

12 December 2020

Na+/K+ATPase as a signaling molecule during bovine sperm capacitation

1 reference

12 December 2020

Endogenous marinobufagenin-like factor in acute plasma volume expansion

1 reference

12 December 2020

Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility

1 reference

12 December 2020

Mechanisms of ouabain toxicity

1 reference

12 December 2020

Phosphoinositide-3 kinase binds to a proline-rich motif in the Na+, K+-ATPase alpha subunit and regulates its trafficking

1 reference

12 December 2020

IRBIT, an inositol 1,4,5-trisphosphate receptor-binding protein, specifically binds to and activates pancreas-type Na+/HCO3- cotransporter 1 (pNBC1)

1 reference

12 December 2020

Antiapoptotic effect of ouabain on human umbilical vein endothelial cells

1 reference

12 December 2020

Inotropic action of digitalis and ion transport

1 reference

12 December 2020

Marinobufagenin stimulates fibroblast collagen production and causes fibrosis in experimental uremic cardiomyopathy

1 reference

12 December 2020

A novel endogenous digitalis, telocinobufagin, exhibits elevated plasma levels in patients with terminal renal failure

1 reference

12 December 2020

Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth

1 reference

12 December 2020

Ouabain decreases sarco(endo)plasmic reticulum calcium ATPase activity in rat hearts by a process involving protein oxidation.

1 reference

12 December 2020

Polyoma virus transforming protein associates with the product of the c-src cellular gene

1 reference

12 December 2020

Cardiotonic steroids stimulate glycogen synthesis in human skeletal muscle cells via a Src- and ERK1/2-dependent mechanism

1 reference

12 December 2020

Molecular mechanism of cofilin dephosphorylation by ouabain

1 reference

12 December 2020

Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

1 reference

12 December 2020

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

1 reference

12 December 2020

Distinct Role of the N-terminal Tail of the Na,K-ATPase Catalytic Subunit as a Signal Transducer

1 reference

12 December 2020

Biology, structure and mechanism of P-type ATPases

1 reference

12 December 2020

Ouabain activates signaling pathways associated with cell death in human neuroblastoma

1 reference

12 December 2020

The interaction of Src and RACK1 is enhanced by activation of protein kinase C and tyrosine phosphorylation of RACK1

1 reference

12 December 2020

The Na,K-ATPase alpha4 isoform from humans has distinct enzymatic properties and is important for sperm motility

1 reference

12 December 2020

Binding of Src to Na+/K+-ATPase forms a functional signaling complex

1 reference

12 December 2020

Ouabain is a potent promoter of growth and activator of ERK1/2 in ouabain-resistant rat renal epithelial cells

1 reference

12 December 2020

Ouabain stimulates endothelin release and expression in human endothelial cells without inhibiting the sodium pump

1 reference

12 December 2020

The pump and leak steady-state concept with a variety of regulated leak pathways

1 reference

12 December 2020

10.1007/S00424-008-0470-0

Identifiers

DOI

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18 August 2017

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