(Q37094730)

18 August 2017

1 reference

title

Novel interactions of perlecan: unraveling perlecan's role in angiogenesis (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6914311&resulttype=core&format=json

13 May 2020

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2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6914311&resulttype=core&format=json

13 May 2020

author name string

Gregory Bix

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6914311&resulttype=core&format=json

13 May 2020

publication date

1 May 2008

1 reference

Microscopy Research and Technique

18 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6914311&resulttype=core&format=json

13 May 2020

volume

71

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6914311&resulttype=core&format=json

13 May 2020

page(s)

339-348

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6914311&resulttype=core&format=json

13 May 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6914311&resulttype=core&format=json

Suppression of autocrine and paracrine functions of basic fibroblast growth factor by stable expression of perlecan antisense cDNA

13 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.20562

Endothelial heparan sulfate proteoglycan. I. Inhibitory effects on smooth muscle cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.20562

Role of angiogenesis in tumor growth and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.20562

Heparan sulfate proteoglycans: intricate molecules with intriguing functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.20562

Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.20562

The biology of perlecan: the multifaceted heparan sulphate proteoglycan of basement membranes and pericellular matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.20562

Perlecan and tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.20562

Complex patterns of alternative splicing mediate the spatial and temporal distribution of perlecan/UNC-52 in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.20562

Vascular cell-derived heparan sulfate shows coupled inhibition of basic fibroblast growth factor binding and mitogenesis in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FJEMT.20562

The protein core of the proteoglycan perlecan binds specifically to fibroblast growth factor-7

21 January 2018

1 reference

12 December 2020

Proteoglycans and tumor progression: Janus-faced molecules with contradictory functions in cancer.

1 reference

12 December 2020

Localization of glycosaminoglycan substitution sites on domain V of mouse perlecan

1 reference

12 December 2020

Acetylcholinesterase clustering at the neuromuscular junction involves perlecan and dystroglycan

1 reference

12 December 2020

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

1 reference

12 December 2020

Drosophila perlecan modulates FGF and hedgehog signals to activate neural stem cell division.

1 reference

12 December 2020

Heparan sulfate: a complex polymer charged with biological activity

1 reference

12 December 2020

Structural characterization of recombinant domain II of the basement membrane proteoglycan perlecan.

1 reference

12 December 2020

Structural and functional mutations of the perlecan gene cause Schwartz-Jampel syndrome, with myotonic myopathy and chondrodysplasia

1 reference

12 December 2020

Assignment of the perlecan (heparan sulfate proteoglycan) gene to mouse chromosome 4

1 reference

12 December 2020

Structural and functional characterization of the human perlecan gene promoter. Transcriptional activation by transforming growth factor-beta via a nuclear factor 1-binding element

1 reference

12 December 2020

Human perlecan immunopurified from different endothelial cell sources has different adhesive properties for vascular cells.

1 reference

12 December 2020

Progranulin gene expression regulates epithelial cell growth and promotes tumor growth in vivo

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12 December 2020

Identification of sites in domain I of perlecan that regulate heparan sulfate synthesis

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12 December 2020

Mapping of the binding of platelet-derived growth factor to distinct domains of the basement membrane proteins BM-40 and perlecan and distinction from the BM-40 collagen-binding epitope.

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12 December 2020

Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization

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12 December 2020

Development of the coronary arteries in a murine model of transposition of great arteries

1 reference

12 December 2020

Perlecan in human bone marrow: a growth-factor-presenting, but anti-adhesive, extracellular matrix component for hematopoietic cells

1 reference

12 December 2020

Specific binding of basic fibroblast growth factor to basement membrane-like structures and to purified heparan sulfate proteoglycan of the EHS tumor.

1 reference

12 December 2020

UNC-52/perlecan affects gonadal leader cell migrations in C. elegans hermaphrodites through alterations in growth factor signaling

1 reference

12 December 2020

Purification and characterization of perlecan fragment in urine of end-stage renal failure patients

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12 December 2020

Expression of the heparan sulfate proteoglycan, perlecan, during mouse embryogenesis and perlecan chondrogenic activity in vitro

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12 December 2020

Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation

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12 December 2020

Endothelial cells interact with the core protein of basement membrane perlecan through beta 1 and beta 3 integrins: an adhesion modulated by glycosaminoglycan

1 reference

12 December 2020

Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis

1 reference

12 December 2020

l(1)trol and l(1)devl, loci affecting the development of the adult central nervous system in Drosophila melanogaster.

1 reference

12 December 2020

Perlecan, the large low-density proteoglycan of basement membranes: structure and variant forms.

1 reference

12 December 2020

Perlecan signaling: helping hedgehog stimulate prostate cancer growth

1 reference

12 December 2020

Wound healing in the alpha2beta1 integrin-deficient mouse: altered keratinocyte biology and dysregulated matrix metalloproteinase expression

1 reference

12 December 2020

Cell autonomous expression of perlecan and plasticity of cell shape in embryonic muscle of Caenorhabditis elegans

1 reference

12 December 2020

Contributions of the LG modules and furin processing to laminin-2 functions

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12 December 2020

Perlecan participates in proliferation activation of quiescent Drosophila neuroblasts.

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12 December 2020

Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia

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12 December 2020

Perlecan: the multidomain heparan sulphate proteoglycan of basement membrane and extracellular matrix.

1 reference

12 December 2020

Structural characterization of the complete human perlecan gene and its promoter

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12 December 2020

Microfibrils at basement membrane zones interact with perlecan via fibrillin-1

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12 December 2020

A role for perlecan in the suppression of growth and invasion in fibrosarcoma cells

1 reference

12 December 2020

Structural basis of glycosaminoglycan modification and of heterotypic interactions of perlecan domain V

1 reference

12 December 2020

Mutations in the unc-52 gene responsible for body wall muscle defects in adult Caenorhabditis elegans are located in alternatively spliced exons

1 reference

12 December 2020

Tumor formation dependent on proteoglycan biosynthesis

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12 December 2020

Biosynthesis of heparan sulfate proteoglycan by human colon carcinoma cells and its localization at the cell surface

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12 December 2020

Perlecan is responsible for thrombospondin 1 binding on the cell surface of cultured porcine endothelial cells

1 reference

12 December 2020

Fibroblast growth factor-binding protein is a novel partner for perlecan protein core

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12 December 2020

Perlecan up-regulation of FRNK suppresses smooth muscle cell proliferation via inhibition of FAK signaling

1 reference

12 December 2020

Perlecan, the major proteoglycan of basement membranes, is altered in patients with Schwartz-Jampel syndrome (chondrodystrophic myotonia).

1 reference

12 December 2020

Apoptosis of endothelial cells triggers a caspase-dependent anti-apoptotic paracrine loop active on VSMC.

1 reference

12 December 2020

Perlecan maintains the integrity of cartilage and some basement membranes

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12 December 2020

Recombinant domain III of perlecan promotes cell attachment through its RGDS sequence

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12 December 2020

Abnormal expression of perlecan proteoglycan in metastatic melanomas

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12 December 2020

The C-terminal domain V of perlecan promotes beta1 integrin-mediated cell adhesion, binds heparin, nidogen and fibulin-2 and can be modified by glycosaminoglycans

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12 December 2020

Thrombospondins 1 and 2 function as inhibitors of angiogenesis

1 reference

12 December 2020

Transcriptional silencing of perlecan gene expression by interferon-gamma

1 reference

12 December 2020

Matrix proteoglycans: from molecular design to cellular function

1 reference

12 December 2020

Interaction of skeletal muscle cells with collagen type IV is mediated by perlecan associated with the cell surface

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12 December 2020

Developmental expression of perlecan during murine embryogenesis

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12 December 2020

Epidermal transformation leads to increased perlecan synthesis with heparin-binding-growth-factor affinity

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12 December 2020

Spectrum ofHSPG2(Perlecan) mutations in patients with Schwartz-Jampel syndrome

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12 December 2020

Heparan sulfate proteoglycans in invasion and metastasis

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12 December 2020

Diversity does make a difference: fibroblast growth factor-heparin interactions

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12 December 2020

Increased intimal hyperplasia and smooth muscle cell proliferation in transgenic mice with heparan sulfate-deficient perlecan

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12 December 2020

Structural and cell-adhesive properties of three recombinant fragments derived from perlecan domain III.

1 reference

12 December 2020

Identification of biologic markers of the premature rupture of fetal membranes: proteomic approach

1 reference

12 December 2020

Phenotypic alterations in Kaposi's sarcoma cells by antisense reduction of perlecan

1 reference

12 December 2020

Extracellular matrices of the avian ovarian follicle. Molecular characterization of chicken perlecan.

1 reference

12 December 2020

Endostatin Associates with Lipid Rafts and Induces Reorganization of the Actin Cytoskeleton via Down-regulation of RhoA Activity

1 reference

12 December 2020

Fibroblast growth factor-2.

1 reference

12 December 2020

Platelet-derived growth factor. Structure, function and implications in normal and malignant cell growth

1 reference

12 December 2020

Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway

1 reference

12 December 2020

The effect of human endothelial cell-derived proteoglycans on human smooth muscle cell growth

1 reference

12 December 2020

Perlecan: how does one molecule do so many things?

1 reference

12 December 2020

The role of collagen-derived proteolytic fragments in angiogenesis

1 reference

12 December 2020

A novel interaction between perlecan protein core and progranulin: potential effects on tumor growth

1 reference

12 December 2020

Structure and function of laminin LG modules

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12 December 2020

Proteoglycans of basement membranes

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12 December 2020

Perlecan-induced suppression of smooth muscle cell proliferation is mediated through increased activity of the tumor suppressor PTEN

1 reference

12 December 2020

The leucine-rich repeat protein PRELP binds perlecan and collagens and may function as a basement membrane anchor

1 reference

12 December 2020

Structure of low density heparan sulfate proteoglycan isolated from a mouse tumor basement membrane

1 reference

12 December 2020

Primary structure of the human heparan sulfate proteoglycan from basement membrane (HSPG2/perlecan). A chimeric molecule with multiple domains homologous to the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal

1 reference

12 December 2020

Chondrogenic activity of the heparan sulfate proteoglycan perlecan maps to the N-terminal domain I

1 reference

12 December 2020

Release of basic fibroblast growth factor-heparan sulfate complexes from endothelial cells by plasminogen activator-mediated proteolytic activity

1 reference

12 December 2020

Suppression by heparin of smooth muscle cell proliferation in injured arteries

1 reference

12 December 2020

The degradation of human endothelial cell-derived perlecan and release of bound basic fibroblast growth factor by stromelysin, collagenase, plasmin, and heparanases

1 reference

12 December 2020

Cloning of human heparan sulfate proteoglycan core protein, assignment of the gene (HSPG2) to 1p36.1→p35 and identification of a BamHI restriction fragment length polymorphism

1 reference

12 December 2020

Heparan sulfate proteoglycan of human colon: partial molecular cloning, cellular expression, and mapping of the gene (HSPG2) to the short arm of human chromosome 1.

1 reference

12 December 2020

The type XIII collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin

1 reference

12 December 2020

Recombinant domain IV of perlecan binds to nidogens, laminin-nidogen complex, fibronectin, fibulin-2 and heparin

1 reference

12 December 2020

The N-terminal globular domain of the laminin alpha1 chain binds to alpha1beta1 and alpha2beta1 integrins and to the heparan sulfate-containing domains of perlecan

1 reference

12 December 2020

Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity

1 reference

12 December 2020

Essential contribution of tumor-derived perlecan to epidermal tumor growth and angiogenesis

1 reference

12 December 2020

Endorepellin in vivo: targeting the tumor vasculature and retarding cancer growth and metabolism

1 reference

12 December 2020

Not all perlecans are created equal: interactions with fibroblast growth factor (FGF) 2 and FGF receptors

1 reference

12 December 2020

Perlecan is essential for cartilage and cephalic development

1 reference

12 December 2020

Control of proliferation activation in quiescent neuroblasts of the Drosophila central nervous system.

1 reference

12 December 2020

Endorepellin, a novel inhibitor of angiogenesis derived from the C terminus of perlecan

1 reference

12 December 2020

The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule

1 reference

12 December 2020

Life without perlecan has its problems

1 reference

12 December 2020

Basement membrane proteoglycans: from cellar to ceiling

1 reference

12 December 2020

Human basement membrane heparan sulfate proteoglycan core protein: a 467-kD protein containing multiple domains resembling elements of the low density lipoprotein receptor, laminin, neural cell adhesion molecules, and epidermal growth factor

1 reference

12 December 2020

Products of the unc-52 gene in Caenorhabditis elegans are homologous to the core protein of the mammalian basement membrane heparan sulfate proteoglycan

1 reference

12 December 2020

Perlecan knockdown in metastatic prostate cancer cells reduces heparin-binding growth factor responses in vitro and tumor growth in vivo

1 reference

12 December 2020

Changes in perlecan expression during vascular injury: role in the inhibition of smooth muscle cell proliferation in the late lesion.

1 reference

12 December 2020

Mutations in the sup-38 gene of Caenorhabditis elegans suppress muscle-attachment defects in unc-52 mutants

1 reference

12 December 2020

Structural basis of beta 1 integrin-mediated cell adhesion to a large heparan sulfate proteoglycan from basement membranes.

1 reference

12 December 2020

Heparan sulfate chains of perlecan are indispensable in the lens capsule but not in the kidney

1 reference

12 December 2020

Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice

1 reference

12 December 2020

Perlecan is a component of cartilage matrix and promotes chondrocyte attachment

1 reference

12 December 2020

Role of perlecan in skeletal development and diseases

1 reference

12 December 2020

Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the alpha2beta1-integrin receptor

1 reference

12 December 2020

Dyssegmental dysplasia, Silverman-Handmaker type, is caused by functional null mutations of the perlecan gene.

1 reference

12 December 2020

Dyssegmental dysplasia, Silverman-Handmaker type: unexpected role of perlecan in cartilage development

1 reference

12 December 2020

The core protein of the matrix-associated heparan sulfate proteoglycan binds to fibronectin

1 reference

12 December 2020

Perlecan heparan sulfate proteoglycan: a novel receptor that mediates a distinct pathway for ligand catabolism

1 reference

12 December 2020

Hyperplastic conotruncal endocardial cushions and transposition of great arteries in perlecan-null mice.

1 reference

12 December 2020

Heparan sulfate proteoglycans in glomerular inflammation.

1 reference

12 December 2020

Perlecan: a gem of a proteoglycan

1 reference

12 December 2020

Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis

1 reference

12 December 2020

Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.

1 reference

12 December 2020

Matrix revolutions: "tails" of basement-membrane components with angiostatic functions

1 reference

12 December 2020

Antiangiogenic antithrombin down-regulates the expression of the proangiogenic heparan sulfate proteoglycan, perlecan, in endothelial cells

1 reference

12 December 2020

Expression of cyclin E or DP/E2F rescues the G1 arrest of trol mutant neuroblasts in the Drosophila larval central nervous system.

1 reference

12 December 2020

Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo

1 reference

12 December 2020

BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan

1 reference

12 December 2020

Basement membranes: structure, assembly and role in tumour angiogenesis

1 reference

12 December 2020

Pieces of eight: bioactive fragments of extracellular proteins as regulators of angiogenesis

1 reference

12 December 2020

Suppression of invasive behavior of melanoma cells by stable expression of anti-sense perlecan cDNA.

1 reference

12 December 2020

Angiogenesis in health and disease

1 reference

12 December 2020

Identifiers

DOI

10.1002/JEMT.20562

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6914311&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6914311&resulttype=core&format=json

13 May 2020

1 reference