(Q37097853)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18309313%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

review article

1 reference

title

Hormones of the gut-brain axis as targets for the treatment of upper gastrointestinal disorders (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18309313%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18309313%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

author name string

Kevin Lee

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18309313%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

language of work or name

1 reference

1 March 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18309313%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Drug Discovery

3 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18309313%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18309313%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

page(s)

241-254

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18309313%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18309313%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrd2444

3 January 2020

exact match

0 references

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31 March 2020

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Obesity: should treatments target visceral afferents?

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Abdominal vagal afferent neurones: an important target for the treatment of gastrointestinal dysfunction

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Characterization of vagal pathways mediating gastric accommodation reflex in rats.

31 March 2020

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The blood-brain barrier as a regulatory interface in the gut-brain axes

31 March 2020

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Human interdigestive and postprandial gastrointestinal motor and gastrointestinal hormone patterns.

31 March 2020

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Intraduodenal neuropeptide levels, but not plasma levels, vary in a cyclic fashion with the migrating motor complex.

31 March 2020

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Motilin activates neurons in the rat amygdala and increases gastric motility.

31 March 2020

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Prokineticin-2, motilin, ghrelin and metoclopramide: prokinetic utility in mouse stomach and colon

31 March 2020

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Signals for nausea and emesis: Implications for models of upper gastrointestinal diseases.

31 March 2020

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A cluster of novel serotonin receptor 3-like genes on human chromosome 3.

31 March 2020

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Stimulatory effect of endogenous orexin A on gastric emptying and acid secretion independent of gastrin.

31 March 2020

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Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin

31 March 2020

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Gut vagal afferents are not necessary for the eating-stimulatory effect of intraperitoneally injected ghrelin in the rat

31 March 2020

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Ghrelin does not stimulate food intake in patients with surgical procedures involving vagotomy

31 March 2020

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The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats

31 March 2020

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Growth hormone secretagogue receptor expression in the cells of the stomach-projected afferent nerve in the rat nodose ganglion.

31 March 2020

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Growth hormone secretagogue receptors in rat and human gastrointestinal tract and the effects of ghrelin

31 March 2020

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Ghrelin stimulates motility in the small intestine of rats through intrinsic cholinergic neurons

31 March 2020

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Ghrelin protects against ethanol-induced gastric ulcers in rats: studies on the mechanisms of action

31 March 2020

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Exogenous and endogenous ghrelin in gastroprotection against stress-induced gastric damage

31 March 2020

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Ghrelin and motilin: two sides of one coin?

31 March 2020

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A motilin agonist, erythromycin, decreases circulating growth hormone levels in normal subjects but not in diabetic subjects

31 March 2020

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The rabbit motilin receptor: molecular characterisation and pharmacology.

31 March 2020

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Serum leptin level in patients with functional dyspepsia

31 March 2020

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Anti-emetic activity of ghrelin in ferrets exposed to the cytotoxic anti-cancer agent cisplatin.

31 March 2020

1 reference

Erythromycin accelerates gastric emptying in a dose-response manner in healthy subjects

31 March 2020

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Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake

31 March 2020

1 reference

Intracerebroventricular acute and chronic administration of obestatin minimally affect food intake but not weight gain in the rat.

31 March 2020

1 reference

Obestatin inhibits feeding but does not modulate GH and corticosterone secretion in the rat

31 March 2020

1 reference

Obestatin reduces food intake and suppresses body weight gain in rodents.

31 March 2020

1 reference

Central obestatin administration does not modify either spontaneous or ghrelin-induced food intake in rats.

31 March 2020

1 reference

Little or no ability of obestatin to interact with ghrelin or modify motility in the rat gastrointestinal tract.

31 March 2020

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Effect of peripheral obestatin on gastric emptying and intestinal contractility in rodents.

31 March 2020

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Distribution and biological activity of obestatin in the rat

31 March 2020

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Normal food intake and body weight in mice lacking the G protein-coupled receptor GPR39.

31 March 2020

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Altered gastrointestinal and metabolic function in the GPR39-obestatin receptor-knockout mouse

31 March 2020

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Lack of ghrelin secretion in response to fasting in cholecystokinin-A (-1), -B (-2) receptor-deficient mice.

31 March 2020

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Food for thought: a critique on the hypothesis that endogenous cholecystokinin acts as a physiological satiety factor.

31 March 2020

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Gut peptides and the regulation of appetite.

31 March 2020

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The stomach is a source of leptin

31 March 2020

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Integrated upper gastrointestinal response to food intake

31 March 2020

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Gastric leptin: a putative role in the short-term regulation of food intake

31 March 2020

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Modulation of vagal afferent excitation and reduction of food intake by leptin and cholecystokinin.

31 March 2020

1 reference

Gut peptides in the regulation of food intake and energy homeostasis

31 March 2020

1 reference

Effect of peptide YY3-36 on food intake in humans

31 March 2020

1 reference

Untangling the effects of hunger, anxiety, and nausea on energy intake during intravenous cholecystokinin octapeptide (CCK-8) infusion.

31 March 2020

1 reference

Impacts and patterns of disturbed gastrointestinal function in critically ill patients

31 March 2020

1 reference

Early satiety in cancer patients: a common and important but underrecognized symptom.

31 March 2020

1 reference

Dysaccommodation of the stomach: therapeutic nirvana?

31 March 2020

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Gastrointestinal motility problems in the elderly patient

31 March 2020

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Gastrointestinal disturbances in eating disorders: clinical and neurobiological aspects.

31 March 2020

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Evidence for a vagal pathophysiology for bulimia nervosa and the accompanying depressive symptoms

31 March 2020

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Peripheral and central signals in the control of eating in normal, obese and binge-eating human subjects.

31 March 2020

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Nausea: the neglected symptom?

31 March 2020

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Treatment of nausea and vomiting: gaps in our knowledge.

31 March 2020

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The animal model in food intake regulation: examples from the opioid literature

31 March 2020

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Does the treatment of gastroesophageal reflux disease (GERD) meet patients' needs? A survey-based study

31 March 2020

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Effect of baclofen on esophagogastric motility and gastroesophageal reflux in children with gastroesophageal reflux disease: a randomized controlled trial

31 March 2020

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Esophageal mucosal damage may promote dysmotility and worsen esophageal acid exposure

31 March 2020

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Mechanisms of disease: the pathological basis of gastroparesis--a review of experimental and clinical studies

31 March 2020

1 reference

The difficult patient with gastroparesis.

31 March 2020

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Gastroparesis: prevalence, clinical significance and treatment

31 March 2020

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Functional dyspepsia--a multicausal disease and its therapy

31 March 2020

1 reference

Ghrelin alleviates cancer chemotherapy-associated dyspepsia in rodents.

31 March 2020

1 reference

Functional dyspepsia: drugs for new (and old) therapeutic targets

31 March 2020

1 reference

High interdigestive and postprandial motilin levels in patients with the irritable bowel syndrome

31 March 2020

1 reference

Cisapride and erythromycin prokinetic effects in gastroparesis due to type 1 (insulin-dependent) diabetes mellitus

31 March 2020

1 reference

Prokinetics in patients with gastroparesis: a systematic analysis

31 March 2020

1 reference

Differences between the abilities of tegaserod and motilin receptor agonists to stimulate gastric motility in vitro.

31 March 2020

1 reference

Molecular characterization and distribution of motilin family receptors in the human gastrointestinal tract

31 March 2020

1 reference

Interaction of the growth hormone-releasing peptides ghrelin and growth hormone-releasing peptide-6 with the motilin receptor in the rabbit gastric antrum

31 March 2020

1 reference

Involvement of two different pathways in the motor effects of erythromycin on the gastric antrum in humans

31 March 2020

1 reference

Influence of motilin on gastric fundus tone and on meal-induced satiety in man: role of cholinergic pathways.

31 March 2020

1 reference

Differential contributions of motilin receptor extracellular domains for peptide and non-peptidyl agonist binding and activity

31 March 2020

1 reference

Erythromycin in the short- and long-term control of dyspepsia symptoms in patients with gastroparesis

31 March 2020

1 reference

Efficacy of prolonged administration of intravenous erythromycin in an ambulatory setting as treatment of severe gastroparesis: one center's experience

31 March 2020

1 reference

Erythromycin dose of 70 mg accelerates gastric emptying as effectively as 200 mg in the critically ill.

31 March 2020

1 reference

Effect of altering gastric emptying on postprandial plasma glucose concentrations following a physiologic meal in type-II diabetic patients

31 March 2020

1 reference

The use of erythromycin as a gastrointestinal prokinetic agent in adult critical care: benefits versus risks

31 March 2020

1 reference

Two new peptides to improve post-operative gastric ileus in dog.

31 March 2020

1 reference

Effect of ghrelin and growth hormone-releasing peptide 6 on septic ileus in mice.

31 March 2020

1 reference

Ghrelin increases energy intake in cancer patients with impaired appetite: acute, randomized, placebo-controlled trial

31 March 2020

1 reference

Physiological, pathological and potential therapeutic roles of ghrelin.

31 March 2020

1 reference

Use of novel prokinetic agents to facilitate return of gastrointestinal motility in adult critically ill patients

31 March 2020

1 reference

SR 48692, a specific neurotensin receptor antagonist, has no effect on oesophageal motility in humans

31 March 2020

1 reference

The physiology of gastric emptying

31 March 2020

1 reference

Organization and neurochemistry of vagal preganglionic neurons innervating the lower esophageal sphincter in ferrets.

31 March 2020

1 reference

Potential control of gastroesophageal reflux by local modulation of transient lower esophageal sphincter relaxations

31 March 2020

1 reference

Imaging and modelling of digestion in the stomach and the duodenum

31 March 2020

1 reference

Appetite signaling: from gut peptides and enteric nerves to brain

31 March 2020

1 reference

Extent and direction of ghrelin transport across the blood-brain barrier is determined by its unique primary structure

31 March 2020

1 reference

Gastric satiation is volumetric, intestinal satiation is nutritive

31 March 2020

1 reference

Interactions between gastric emptying and satiety, with special reference to glucagon-like peptide-1.

31 March 2020

1 reference

Interleukins and tumor necrosis factor as inhibitors of food intake

31 March 2020

1 reference

IL-1beta and IL-6 excite neurones and suppress cholinergic neurotransmission in the myenteric plexus of the guinea pig.

31 March 2020

1 reference

Low-dose erythromycin reduces delayed gastric emptying and improves gastric motility after Billroth I pylorus-preserving pancreaticoduodenectomy

31 March 2020

1 reference

Effect of atilmotin on gastrointestinal transit in healthy subjects: a randomized, placebo-controlled study.

31 March 2020

1 reference

Somatostatin and the interdigestive migrating motor complex in man

31 March 2020

1 reference

The influence of the migrating motor complex on the postprandial endocrine response.

31 March 2020

1 reference

Phase III of the migrating motor complex: associated with endogenous xenin plasma peaks and induced by exogenous xenin

31 March 2020

1 reference

Orexin-A expression in human peripheral tissues.

31 March 2020

1 reference

Actions of orexins on individual myenteric neurons of the guinea-pig ileum: orexin A or B?

31 March 2020

1 reference

Localization of orexin-1 receptors to vagal afferent neurons in the rat and humans.

31 March 2020

1 reference

Ghrelin, the peripheral hunger hormone

31 March 2020

1 reference

Rapid changes in the sensitivity of arcuate nucleus neurons to central ghrelin in relation to feeding status.

31 March 2020

1 reference

Ghrelin stimulates gastric emptying and hunger in normal-weight humans.

31 March 2020

1 reference

Ghrelin enhances gastric emptying in diabetic gastroparesis: a double blind, placebo controlled, crossover study.

31 March 2020

1 reference

Influence of ghrelin on gastric emptying and meal-related symptoms in idiopathic gastroparesis.

31 March 2020

1 reference

Ghrelin gastrokinetic action in patients with neurogenic gastroparesis.

31 March 2020

1 reference

Feeding-dependent depression of melanin-concentrating hormone and melanin-concentrating hormone receptor-1 expression in vagal afferent neurones.

31 March 2020

1 reference

Effect of gastrin-17 on lower esophageal sphincter characteristics in man

31 March 2020

1 reference

Peptide YY(1-36) and peptide YY(3-36): Part I. Distribution, release and actions

31 March 2020

1 reference

Pancreatic polypeptide: more than just another gut hormone?

31 March 2020

1 reference

Endogenous glucagon-like peptide 1 controls endocrine pancreatic secretion and antro-pyloro-duodenal motility in humans

31 March 2020

1 reference

A role for pancreatic polypeptide in the regulation of gastric emptying and short-term metabolic control

31 March 2020

1 reference

Amylinergic control of food intake

31 March 2020

1 reference

Role of endogenous amylin in glucagon secretion and gastric emptying in rats demonstrated with the selective antagonist, AC187

31 March 2020

1 reference

Efficacy of mitemcinal, a motilin agonist, on gastrointestinal symptoms in patients with symptoms suggesting diabetic gastropathy: a randomized, multi-center, placebo-controlled trial

31 March 2020

1 reference

New motilin agonists: a long and winding road

31 March 2020

1 reference

Failure of a motilin receptor agonist (ABT-229) to relieve the symptoms of functional dyspepsia in patients with and without delayed gastric emptying: a randomized double-blind placebo-controlled trial

31 March 2020

1 reference

Effects of a motilin receptor agonist (ABT-229) on upper gastrointestinal symptoms in type 1 diabetes mellitus: a randomised, double blind, placebo controlled trial

31 March 2020

1 reference

The effects of ABT-229 and octreotide on interdigestive small bowel motility, bacterial overgrowth and bacterial translocation in rats.

31 March 2020

1 reference

Afferent signals regulating food intake

31 March 2020

1 reference