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XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling.
scientific article published on 07 June 2013
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Europe PubMed Central
PMCID
3746193
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23749209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
title
XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3746193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23749209%20AND%20SRC:MED&resulttype=core&format=json
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2 March 2020
main subject
autophagy
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author
Xing Huang
series ordinal
1
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Europe PubMed Central
PMCID
3746193
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23749209%20AND%20SRC:MED&resulttype=core&format=json
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2 March 2020
author name string
Zhengsheng Wu
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2
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Europe PubMed Central
PMCID
3746193
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23749209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
Yide Mei
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3
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Europe PubMed Central
PMCID
3746193
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23749209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
Mian Wu
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4
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3746193
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2 March 2020
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English
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publication date
7 June 2013
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3746193
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retrieved
2 March 2020
published in
The EMBO Journal
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Europe PubMed Central
PMCID
3746193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23749209%20AND%20SRC:MED&resulttype=core&format=json
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2 March 2020
volume
32
1 reference
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Europe PubMed Central
PMCID
3746193
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2 March 2020
issue
16
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PMCID
3746193
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retrieved
2 March 2020
page(s)
2204-2216
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Europe PubMed Central
PMCID
3746193
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23749209%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 March 2020
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ImageQuant
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Europe PubMed Central
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3746193/fullTextXML
based on heuristic
inferred from PubMed Central ID database lookup
cites work
XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling
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PubMed Central
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14 September 2017
Autophagy and cancer
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14 September 2017
Autophagy: renovation of cells and tissues
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14 September 2017
The dynamic nature of autophagy in cancer
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14 September 2017
Autophagy and aging
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14 September 2017
ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress
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Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase
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14 September 2017
IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer
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Autophagy regulation by p53.
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Regulation of XIAP translation and induction by MDM2 following irradiation
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Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability
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Regulation of apoptosis by XIAP ubiquitin-ligase activity
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Regulation of autophagy by cytoplasmic p53
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Autophagy fights disease through cellular self-digestion
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14 September 2017
Autophagy: process and function
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14 September 2017
Role of autophagy in cancer
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PubMed Central
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14 September 2017
Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation
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PubMed Central
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14 September 2017
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746193
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14 September 2017
Autophagy: from phenomenology to molecular understanding in less than a decade
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746193
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14 September 2017
XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746193
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14 September 2017
Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746193
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14 September 2017
Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746193
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14 September 2017
Critical role for Daxx in regulating Mdm2
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14 September 2017
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
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14 September 2017
Loss of autophagy in the central nervous system causes neurodegeneration in mice
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14 September 2017
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
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14 September 2017
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14 September 2017
Caspases, IAPs and Smac/DIABLO: mechanisms from structural biology
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14 September 2017
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
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14 September 2017
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
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14 September 2017
IAP proteins: blocking the road to death's door
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14 September 2017
Characterization of XIAP-deficient mice
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Expression and prognostic significance of IAP-family genes in human cancers and myeloid leukemias
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14 September 2017
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
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Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746193
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14 September 2017
Induction of autophagy and inhibition of tumorigenesis by beclin 1
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Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
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14 September 2017
X-linked IAP is a direct inhibitor of cell-death proteases
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14 September 2017
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
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An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif
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14 September 2017
An apoptosis-inhibiting gene from a nuclear polyhedrosis virus encoding a polypeptide with Cys/His sequence motifs
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14 September 2017
Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database
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29 September 2017
Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP).
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29 September 2017
Tumor expression of human growth hormone and human prolactin predict a worse survival outcome in patients with mammary or endometrial carcinoma.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746193
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3 September 2018
Frameshift mutation of UVRAG, an autophagy-related gene, in gastric carcinomas with microsatellite instability
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3 September 2018
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3 September 2018
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
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21 January 2018
Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3
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Identifiers
DOI
10.1038/EMBOJ.2013.133
1 reference
stated in
Fatcat
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https://api.fatcat.wiki/v0/release/6khj42st5vggtipjd6qudxhmvi
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
Fatcat ID
release_6khj42st5vggtipjd6qudxhmvi
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/6khj42st5vggtipjd6qudxhmvi
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30 July 2022
based on heuristic
mapped directly with Wikidata item
PMCID
3746193
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/6khj42st5vggtipjd6qudxhmvi
retrieved
30 July 2022
based on heuristic
mapped directly with Wikidata item
PubMed ID
23749209
1 reference
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Fatcat
reference URL
https://api.fatcat.wiki/v0/release/6khj42st5vggtipjd6qudxhmvi
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30 July 2022
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ResearchGate publication ID
237094333
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