(Q37102350)

18 August 2017

Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin (English)

1 reference

18 August 2017

Casie E Soltani

1

1 reference

18 August 2017

Eileen M Hotze

series ordinal

2

1 reference

18 August 2017

Arthur E Johnson

series ordinal

3

1 reference

18 August 2017

Rodney K Tweten

series ordinal

4

1 reference

18 August 2017

language of work or name

English

0 references

publication date

5 April 2007

1 reference

Journal of Biological Chemistry

18 August 2017

1 reference

18 August 2017

282

1 reference

18 August 2017

21

1 reference

18 August 2017

15709-15716

1 reference

The domains of a cholesterol-dependent cytolysin undergo a major FRET-detected rearrangement during pore formation

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Structural basis of pore formation by the bacterial toxin pneumolysin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Vertical collapse of a cytolysin prepore moves its transmembrane beta-hairpins to the membrane

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit beta-strand alignment.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Assembly and topography of the prepore complex in cholesterol-dependent cytolysins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Cholesterol-binding cytolytic protein toxins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

A biotinylated perfringolysin O derivative: a new probe for detection of cell surface cholesterol

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

VMD: visual molecular dynamics

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Human CD59 is a receptor for the cholesterol-dependent cytolysin intermedilysin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Secretory proteins move through the endoplasmic reticulum membrane via an aqueous, gated pore.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Kinetic aspects of the aggregation of Clostridium perfringens theta-toxin on erythrocyte membranes. A fluorescence energy transfer study.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3746338

Contribution of tryptophan residues to the structural changes in perfringolysin O during interaction with liposomal membranes

27 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701173200

Contribution of individual tryptophan residues to the structure and activity of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701173200

The C-terminal domain of perfringolysin O is an essential cholesterol-binding unit targeting to cholesterol-rich microdomains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701173200

The human-specific action of intermedilysin, a homolog of streptolysin O, is dictated by domain 4 of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701173200

The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701173200

Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming ToxinClostridium perfringensPerfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701173200

The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins

21 January 2018

1 reference

12 December 2020

Role of the essential thiol group in the thiol-activated cytolysin from Clostridium perfringens

1 reference

12 December 2020

A cytolysin, theta-toxin, preferentially binds to membrane cholesterol surrounded by phospholipids with 18-carbon hydrocarbon chains in cholesterol-rich region

1 reference

12 December 2020

The projection structure of perfringolysin O (Clostridium perfringens theta-toxin)

1 reference

12 December 2020

The signal sequence moves through a ribosomal tunnel into a noncytoplasmic aqueous environment at the ER membrane early in translocation

1 reference

12 December 2020

Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: change in the aromatic side chains upon binding and insertion

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M701173200

1 reference

18 August 2017

1 reference

18 August 2017

PubMed publication ID

17412689

1 reference