(Q37104728)

18 August 2017

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title

Post-translational modifications of recombinant proteins: significance for biopharmaceuticals (English)

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18 August 2017

Nigel Jenkins

1

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18 August 2017

Lisa Murphy

series ordinal

2

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18 August 2017

Ray Tyther

series ordinal

3

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18 August 2017

1 June 2008

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18 August 2017

Molecular Biotechnology

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18 August 2017

39

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18 August 2017

2

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18 August 2017

113-118

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https://scigraph.springernature.com/pub.10.1007/s12033-008-9049-4

18 August 2017

0 references

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12 December 2020

Comparison of methionine oxidation in thermal stability and chemically stressed samples of a fully human monoclonal antibody

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12 December 2020

Selective deamidation of recombinant human stem cell factor during in vitro aging: isolation and characterization of the aspartyl and isoaspartyl homodimers and heterodimers

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12 December 2020

Quantitation of aggregates in therapeutic proteins using sedimentation velocity analytical ultracentrifugation: practical considerations that affect precision and accuracy

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12 December 2020

Stability of human serum albumin during bioprocessing: denaturation and aggregation during processing of albumin paste

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Clinical investigation of the immunogenicity of interferon-alpha 2a

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12 December 2020

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12 December 2020

Co-expression of molecular chaperones does not improve the heterologous expression of mammalian G-protein coupled receptor expression in yeast

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12 December 2020

Overexpression of GRP78 mitigates stress induction of glucose regulated proteins and blocks secretion of selective proteins in Chinese hamster ovary cells

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12 December 2020

An approach to understand the complexation of supramolecular dye Congo red with immunoglobulin L chain lambda.

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12 December 2020

Effects of sucrose on rFVIIa aggregation and methionine oxidation.

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12 December 2020

Structure-immunogenicity relationships of therapeutic proteins

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12 December 2020

Glutathione is required to regulate the formation of native disulfide bonds within proteins entering the secretory pathway

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12 December 2020

Oxidation of either methionine 351 or methionine 358 in alpha 1-antitrypsin causes loss of anti-neutrophil elastase activity

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12 December 2020

Identification and characterization of deamidation sites in the conserved regions of human immunoglobulin gamma antibodies

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12 December 2020

The role of glutathione in disulphide bond formation and endoplasmic-reticulum-generated oxidative stress.

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12 December 2020

Mammalian cell factories for efficient and stable protein expression

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12 December 2020

A specific molar ratio of stabilizer to protein is required for storage stability of a lyophilized monoclonal antibody

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12 December 2020

Chaperone selection during glycoprotein translocation into the endoplasmic reticulum.

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12 December 2020

Influence of aggregation on immunogenicity of recombinant human Factor VIII in hemophilia A mice

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12 December 2020

Cooverexpression of chaperones for enhanced secretion of a single-chain antibody fragment in Pichia pastoris.

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12 December 2020

Quantitative analysis of transcription and translation in gene amplified Chinese hamster ovary cells on the basis of a kinetic model

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12 December 2020

Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed

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12 December 2020

Antioxidants for prevention of methionine oxidation in recombinant monoclonal antibody HER2

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12 December 2020

Review: Why is arginine effective in suppressing aggregation?

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12 December 2020

EST sequencing for gene discovery in Chinese hamster ovary cells

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12 December 2020

Protein aggregation and bioprocessing

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12 December 2020

'Biogenerics': the off-patent biotech products

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12 December 2020

Protein folding and quality control in the endoplasmic reticulum

1 reference

12 December 2020

Simultaneous determination of protein aggregation, degradation, and absolute molecular weight by size exclusion chromatography-multiangle laser light scattering

1 reference

12 December 2020

10.1007/S12033-008-9049-4

Identifiers

DOI

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release_wibmnyrvd5fd5ptdmw3h6ouxye

18 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/wibmnyrvd5fd5ptdmw3h6ouxye

24 November 2022

mapped directly with Wikidata item

1 reference