(Q37105086)

18 August 2017

A regulator of G protein signaling interaction surface linked to effector specificity (English)

1 reference

18 August 2017

M E Sowa

1

1 reference

18 August 2017

W He

series ordinal

2

1 reference

18 August 2017

T G Wensel

series ordinal

3

1 reference

18 August 2017

O Lichtarge

series ordinal

4

1 reference

18 August 2017

language of work or name

English

0 references

publication date

1 February 2000

1 reference

Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

1 reference

18 August 2017

97

1 reference

18 August 2017

4

1 reference

18 August 2017

1483-1488

1 reference

Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

Gbeta5 prevents the RGS7-Galphao interaction through binding to a distinct Ggamma-like domain found in RGS7 and other RGS proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein beta subunit

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

The helical domain of a G protein alpha subunit is a regulator of its effector

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

RGSZ1, a Gz-selective RGS protein in brain. Structure, membrane association, regulation by Galphaz phosphorylation, and relationship to a Gz gtpase-activating protein subfamily

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

RGS9, a GTPase accelerator for phototransduction

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

RGS4 and GAIP are GTPase-activating proteins for Gq alpha and block activation of phospholipase C beta by gamma-thio-GTP-Gq alpha

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

Evolutionarily conserved Galphabetagamma binding surfaces support a model of the G protein-receptor complex

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

An evolutionary trace method defines binding surfaces common to protein families

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

The 2.0 A crystal structure of a heterotrimeric G protein

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteins

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

A site on transducin alpha-subunit of interaction with the polycationic region of cGMP phosphodiesterase inhibitory subunit.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

A comprehensive set of sequence analysis programs for the VAX

14 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

14 September 2017

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Progressive sequence alignment as a prerequisite to correct phylogenetic trees

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

Identification of effector residues on photoreceptor G protein, transducin.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

Regulation of transducin GTPase activity by human retinal RGS.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=26460

The retinal specific protein RGS-r competes with the gamma subunit of cGMP phosphodiesterase for the alpha subunit of transducin and facilitates signal termination

27 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Identification of functional surfaces of the zinc binding domains of intracellular receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Conic: a fast renderer for space-filling molecules with shadows

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Regulators of G protein signaling proteins as determinants of the rate of desensitization of presynaptic calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Receptor and betagamma binding sites in the alpha subunit of the retinal G protein transducin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

RGS Proteins Determine Signaling Specificity of Gq-coupled Receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Phospholipase C-beta1 directly accelerates GTP hydrolysis by Galphaq and acceleration is inhibited by Gbeta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Mapping of effector binding sites of transducin alpha-subunit using G alpha t/G alpha i1 chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Enzymology of GTPase acceleration in phototransduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Modulation of transducin GTPase activity by chimeric RGS16 and RGS9 regulators of G protein signaling and the effector molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

The alpha-helical domain of Galphat determines specific interaction with regulator of G protein signaling 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

A site on rod G protein alpha subunit that mediates effector activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Interaction sites of the COOH-terminal region of the gamma subunit of cGMP phosphodiesterase with the GTP-bound alpha subunit of transducin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Roles of the transducin alpha-subunit alpha4-helix/alpha4-beta6 loop in the receptor and effector interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Identification of the Gbeta5-RGS7 protein complex in the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

The membrane association domain of RGS16 contains unique amphipathic features that are conserved in RGS4 and RGS5

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Mechanism of allosteric regulation of the rod cGMP phosphodiesterase activity by the helical domain of transducin alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.030409597

Sites of interaction between rod G-protein alpha-subunit and cGMP-phosphodiesterase gamma-subunit. Implications for the phosphodiesterase activation mechanism

21 January 2018

1 reference

12 December 2020

Enhancement of rod outer segment GTPase accelerating protein activity by the inhibitory subunit of cGMP phosphodiesterase

1 reference

12 December 2020

Regulation of transducin GTPase activity in bovine rod outer segments

1 reference

12 December 2020

Activation of transducin guanosine triphosphatase by two proteins of the RGS family

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.030409597

1 reference

18 August 2017

0 references

1 reference

18 August 2017

PubMed publication ID

10677488

1 reference