(Q37106813)

18 August 2017

1 reference

title

Lost in translation: problems and pitfalls in translating laboratory observations to clinical utility (English)

1 reference

18 August 2017

Richard Simon

1

1 reference

18 August 2017

1 November 2008

1 reference

European Journal of Cancer

18 August 2017

1 reference

18 August 2017

44

1 reference

18 August 2017

18

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18 August 2017

2707-2713

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How large a training set is needed to develop a classifier for microarray data?

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Critical review of published microarray studies for cancer outcome and guidelines on statistical analysis and reporting

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Concordance among gene-expression-based predictors for breast cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

A comparison of univariate and multivariate gene selection techniques for classification of cancer datasets

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Sample size planning for developing classifiers using high-dimensional DNA microarray data

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Thousands of samples are needed to generate a robust gene list for predicting outcome in cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Bias in error estimation when using cross-validation for model selection

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Use of genomic signatures in therapeutics development in oncology and other diseases

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

When is a genomic classifier ready for prime time?

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Clinical trial designs for predictive marker validation in cancer treatment trials

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Clinical trial design for microarray predictive marker discovery and assessment

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Clinical application of cDNA microarrays in oncology

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Pitfalls in the use of DNA microarray data for diagnostic and prognostic classification

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Selection bias in gene extraction on the basis of microarray gene-expression data

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Gene expression profiling predicts clinical outcome of breast cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

The hypercycle. A principle of natural self-organization. Part A: Emergence of the hypercycle

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Prediction error estimation: a comparison of resampling methods

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Bioinformatics in cancer therapeutics--hype or hope?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

On the dynamics of breast tumor development in women carrying germline BRCA1 and BRCA2 mutations

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Finding clinical meaning in cancer data

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Translational investigators: life sciences' application engineers

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Biomarker-adaptive threshold design: a procedure for evaluating treatment with possible biomarker-defined subset effect.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Estimating the number of rate limiting genomic changes for human breast cancer.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Microarrays: retracing steps

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

Serum proteomics profiling—a young technology begins to mature

4 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646591

A paradigm for class prediction using gene expression profiles

4 December 2018

1 reference

12 December 2020

Evaluating the efficiency of targeted designs for randomized clinical trials

1 reference

12 December 2020

Statistical model to determine the relationship of response and survival in patients with advanced ovarian cancer treated with chemotherapy

1 reference

12 December 2020

On the efficiency of targeted clinical trials

1 reference

12 December 2020

Prediction of cancer outcome with microarrays: a multiple random validation strategy

1 reference

12 December 2020

Translating research into clinical practice: deliberations from the American Association for Cancer Research

1 reference

12 December 2020

Adaptive signature design: an adaptive clinical trial design for generating and prospectively testing a gene expression signature for sensitive patients

1 reference

12 December 2020

Sustaining the clinical in clinical translational research

1 reference

12 December 2020

Development and evaluation of therapeutically relevant predictive classifiers using gene expression profiling

1 reference

12 December 2020

Development and clinical utility of a 21-gene recurrence score prognostic assay in patients with early breast cancer treated with tamoxifen

1 reference

12 December 2020

A method for testing a prespecified subgroup in clinical trials

1 reference

12 December 2020

10.1016/J.EJCA.2008.09.009

Identifiers

DOI

1 reference

18 August 2017

1 reference

18 August 2017

1 reference

PMCID

2646591