(Q37117259)

18 August 2017

Replacement of in vivo acute oral toxicity studies by in vitro cytotoxicity methods: opportunities, limits and regulatory status (English)

1 reference

18 August 2017

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Ute Ukelis

1

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18 August 2017

Peter-Jürgen Kramer

series ordinal

2

1 reference

18 August 2017

Klaus Olejniczak

series ordinal

3

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18 August 2017

Stefan O Mueller

series ordinal

4

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18 August 2017

language of work or name

English

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publication date

21 February 2008

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Regulatory Toxicology and Pharmacology

18 August 2017

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18 August 2017

51

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18 August 2017

1

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18 August 2017

108-118

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Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells

18 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Overview of the Final MEIC Results: I. The In Vitro--In Vitro Evaluation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Guidance on good cell culture practice. a report of the second ECVAM task force on good cell culture practice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Cell volume control and signal transduction in apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Compartmentation of Nrf-2 redox control: regulation of cytoplasmic activation by glutathione and DNA binding by thioredoxin-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Animal testing and alternative approaches for the human health risk assessment under the proposed new European chemicals regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Can the pharmaceutical industry reduce attrition rates?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Drug-induced hepatotoxicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Concordance of the toxicity of pharmaceuticals in humans and in animals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Ensuring quality of in vitro alternative test methods: Current practice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Molecular mechanisms of apoptosis induced by cytotoxic chemicals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Effects of cell culture conditions on primary rat hepatocytes-cell morphology and differential gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

Applications of cytotoxicity assays and pre-lethal mechanistic assays for assessment of human hepatotoxicity potential

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YRTPH.2008.02.002

10.1016/J.YRTPH.2008.02.002

7 January 2021

Identifiers

DOI

1 reference

18 August 2017

1 reference