(Q37118150)

18 August 2017

1 reference

title

Multiple roles for CD4+ T cells in anti-tumor immune responses (English)

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18 August 2017

Richard Kennedy

1

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18 August 2017

Esteban Celis

series ordinal

2

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18 August 2017

publication date

1 April 2008

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18 August 2017

published in

Immunological Reviews

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18 August 2017

volume

222

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18 August 2017

page(s)

129-144

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Helper activity is required for the in vivo generation of cytotoxic T lymphocytes

18 August 2017

cites work

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21 January 2018

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21 January 2018

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Defining MHC class II T helper epitopes for WT1 tumor antigen

21 January 2018

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Central memory and effector memory T cell subsets: function, generation, and maintenance

21 January 2018

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Understanding the generation and function of memory T cell subsets

21 January 2018

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21 January 2018

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OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

21 January 2018

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Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

21 January 2018

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IL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory

21 January 2018

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Dendritic cell-mediated T cell polarization

21 January 2018

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Innate immune recognition

21 January 2018

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Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering

21 January 2018

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A three-cell model for activation of naïve T helper cells.

21 January 2018

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Signaling pathways in Th2 development

21 January 2018

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Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

21 January 2018

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Regulatory T-cells in the control of immunological diseases

21 January 2018

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Tregs and rethinking cancer immunotherapy

21 January 2018

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CD4 regulatory T cells in human cancer pathogenesis

21 January 2018

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Regulatory T cells and Toll-like receptors in tumor immunity

21 January 2018

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Immunoregulatory T cells in tumor immunity

21 January 2018

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Natural regulatory T cells: mechanisms of suppression

21 January 2018

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T helper cell effector fates--who, how and where?

21 January 2018

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Regulatory T cells and cancer

21 January 2018

1 reference

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Helper T cell differentiation enters a new era: le roi est mort; vive le roi!

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

21 January 2018

1 reference

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T(H)-17 cells in the circle of immunity and autoimmunity

21 January 2018

1 reference

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Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment

21 January 2018

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IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

21 January 2018

1 reference

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T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Follicular B helper T cells in antibody responses and autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Understanding the function of CD1-restricted T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Mouse CD1-specific NK1 T cells: development, specificity, and function

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Unmasking immunosurveillance against a syngeneic colon cancer by elimination of CD4+ NKT regulatory cells and IL-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

CD1d-restricted natural killer T cells can down-regulate tumor immunosurveillance independent of interleukin-4 receptor-signal transducer and activator of transcription 6 or transforming growth factor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Going both ways: immune regulation via CD1d-dependent NKT cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

NKT cell defects in NOD mice suggest therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Janus-like role of regulatory iNKT cells in autoimmune disease and tumour immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

The carrier effect in the secondary response to hapten-protein conjugates. II. Cellular cooperation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

The central role of CD4(+) T cells in the antitumor immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Interleukin 7 induces CD4+ T cell-dependent tumor rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Augmenting T helper cell immunity in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Dendritic cell-induced activation of adaptive and innate antitumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Help for cytotoxic-T-cell responses is mediated by CD40 signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Cutting edge: CD4+ T cell help can be essential for primary CD8+ T cell responses in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Cutting Edge: Precursor Frequency Affects the Helper Dependence of Cytotoxic T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Induction of CD70 on dendritic cells through CD40 or TLR stimulation contributes to the development of CD8+ T cell responses in the absence of CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Mini-review CD4 T cells are required for CD8 T cell memory generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Compromised influenza virus-specific CD8(+)-T-cell memory in CD4(+)-T-cell-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

The generation of protective memory-like CD8+ T cells during homeostatic proliferation requires CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Rescue of memory CD8+ T cell reactivity in peptide/TLR9 ligand immunization by codelivery of cytokines or CD40 ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

In vivo ligation of CD40 enhances priming against the endogenous tumor antigen and promotes CD8+ T cell effector function in SV40 T antigen transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Activation-induced apoptosis in lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Activation-induced nonresponsiveness: a Th-dependent regulatory checkpoint in the CTL response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

CD28/B7 costimulation: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

The Yin and Yang of T cell costimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

“Ia-like” antigens on human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Ia determinants on stimulated human T lymphocytes. Occurrence on mitogen- and antigen-activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Exhaustion of cytotoxic T cells during adoptive immunotherapy of virus carrier mice can be prevented by B cells or CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

T helper lymphocytes rescue CTL from activation-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

A fail-safe mechanism for maintaining self-tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Peripheral human T cells sensitized in mixed leukocyte culture synthesize and express Ia-like antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Spontaneous internalization of Class I major histocompatibility complex molecules in T lymphoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Antigen presentation by mouse CD4+ T cells involving acquired MHC class II:peptide complexes: another mechanism to limit clonal expansion?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

TCR-Mediated internalization of peptide-MHC complexes acquired by T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Intercellular transfer of antigen-presenting cell determinants onto T cells: molecular mechanisms and biological significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Cutting edge: CTLs rapidly capture membrane fragments from target cells in a TCR signaling-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

T cells down-modulate peptide-MHC complexes on APCs in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Antigen presentation by T cells: T cell receptor ligation promotes antigen acquisition from professional antigen-presenting cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Acquisition of functional MHC class II/peptide complexes by T cells during thymic development and CNS-directed pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Acquisition of CD80 by human T cells at early stages of activation: functional involvement of CD80 acquisition in T cell to T cell interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Acquisition of CD80 (B7-1) by T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Intercellular exchange of class II major histocompatibility complex/peptide complexes is a conserved process that requires activation of T cells but is constitutive in other types of antigen presenting cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Class II MHC/peptide complexes on T cell antigen-presenting cells: agonistic antigen recognition inhibits subsequent antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Antigen-independent acquisition of MHC class II molecules by human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Alternative pathways for processing exogenous and endogenous antigens that can generate peptides for MHC class I-restricted presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Recycling MHC class I molecules and endosomal peptide loading

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Antigen loading of MHC class I molecules in the endocytic tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Trafficking of spontaneously endocytosed MHC proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Use of antibody/peptide constructs to direct antigenic peptides to T cells: Evidence for T cell processing and presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

T cells can present antigens such as HIV gp120 targeted to their own surface molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Transferrin receptor mediates uptake and presentation of hepatitis B envelope antigen by T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: effect of HIV sequence variation and a mechanism for CD4+ cell depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

A new dynamic model of CD8+ T effector cell responses via CD4+ T helper-antigen-presenting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

The B7 adhesion molecule is expressed on activated human T cells: functional involvement in T-T cell interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Early signaling defects in human T cells anergized by T cell presentation of autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Fratricide among CD8(+) T lymphocytes naturally infected with human T cell lymphotropic virus type I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Regulation of tumour immunity by CD25+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Peptide vaccine given with a Toll-like receptor agonist is effective for the treatment and prevention of spontaneous breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

A mouse mutant p53 product recognized by CD4+ and CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Peptide‐specific activation of cytolytic CD4+ T lymphocytes against tumor cells bearing mutated epitopes of K‐ras p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

MHC class I-restricted determinants on the glutamic acid decarboxylase 65 molecule induce spontaneous CTL activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Autoimmune diabetes: the role of T cells, MHC molecules and autoantigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Hepatitis B virus immunopathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Vaccinia virus-specific CD4+ T cell responses target a set of antigens largely distinct from those targeted by CD8+ T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

A consensus epitope prediction approach identifies the breadth of murine T(CD8+)-cell responses to vaccinia virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

CD40–CD40Ligand interactions and their role in cytotoxic T lymphocyte priming and anti-tumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

Antigen-specific interaction between T and B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-065X.2008.00616.X

10.1111/J.1600-065X.2008.00616.X

21 January 2018

Identifiers

DOI

1 reference

18 August 2017

1 reference