(Q37119764)

English

Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva.

scientific article published on 06 August 2008

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Constitutively activated ALK2 and increased SMAD1/5 cooperatively induce bone morphogenetic protein signaling in fibrodysplasia ossificans progressiva (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

fibrodysplasia ossificans progressiva

0 references

1 reference

based on heuristic

inferred from title

26

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

author name string

Toru Fukuda

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Masakazu Kohda

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Kazuhiro Kanomata

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Junya Nojima

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Atsushi Nakamura

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Jyunji Kamizono

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Yasuo Noguchi

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Kiyofumi Iwakiri

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Takeo Kondo

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Junichi Kurose

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Ken-ichi Endo

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Takeshi Awakura

12

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Junichi Fukushi

13

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Yasuharu Nakashima

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Tomohiro Chiyonobu

15

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Akira Kawara

16

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Yoshihiro Nishida

17

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Ikuo Wada

18

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Masumi Akita

19

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Tetsuo Komori

20

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Konosuke Nakayama

21

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Akira Nanba

22

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Yuichi Maruki

23

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Tetsuya Yoda

24

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Hiroshi Tomoda

25

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Eileen M Shore

27

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Frederick S Kaplan

28

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Kohei Miyazono

29

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Masaru Matsuoka

30

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Kenji Ikebuchi

31

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Akira Ohtake

32

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Hiromi Oda

33

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Eijiro Jimi

34

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Ichiro Owan

35

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Yasushi Okazaki

36

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Takenobu Katagiri

37

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

language of work or name

0 references

publication date

6 August 2008

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

284

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

7149-7156

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Bone morphogenetic protein-9 is a circulating vascular quiescence factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Dysregulation of the BMP-4 signaling pathway in fibrodysplasia ossificans progressiva

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

BMP receptor signaling: transcriptional targets, regulation of signals, and signaling cross-talk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Synergistic effects of different bone morphogenetic protein type I receptors on alkaline phosphatase induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Phosphorylation of Ser165 in TGF-beta type I receptor modulates TGF-beta1-induced cellular responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Bone: formation by autoinduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Novel regulators of bone formation: molecular clones and activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Fibrodysplasia ossificans progressiva: a clue from the fly?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

14 September 2017

Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

29 September 2017

Induction of Smad6 mRNA by bone morphogenetic proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

29 September 2017

Constitutively active BMP type I receptors transduce BMP-2 signals without the ligand in C2C12 myoblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

29 September 2017

Bone morphogenetic protein-2 inhibits terminal differentiation of myogenic cells by suppressing the transcriptional activity of MyoD and myogenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

29 September 2017

Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

29 September 2017

Severe restriction in jaw movement after routine injection of local anesthetic in patients who have fibrodysplasia ossificans progressiva.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

27 June 2018

Purification and identification of a BMP-like factor from bovine serum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

3 September 2018

In vivo somatic cell gene transfer of an engineered Noggin mutein prevents BMP4-induced heterotopic ossification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

3 September 2018

Smad6 inhibits signalling by the TGF-beta superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

3 September 2018

Opposing effects of activin A and follistatin on developing skeletal muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

3 September 2018

Bone morphogenetic protein 2/4 in early fibromatous lesions of fibrodysplasia ossificans progressiva.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

3 September 2018

Fibrodysplasia ossificans progressiva. The clinical features and natural history of 34 patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652274

3 September 2018

The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva. A study of forty-four patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The histopathology of fibrodysplasia ossificans progressiva. An endochondral process

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic transmission of fibrodysplasia ossificans progressiva. Report of a family

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Permanent heterotopic ossification at the injection site after diphtheria-tetanus-pertussis immunizations in children who have fibrodysplasia ossificans progressiva

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effects of activin-A on osteoblast differentiation during cultures of fetal rat calvarial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulation of the BMP-p38 MAPK signaling pathway in cells from patients with fibrodysplasia ossificans progressiva (FOP)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hematopoietic stem-cell contribution to ectopic skeletogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ACVR1 617G>A mutation is also recurrent in three Japanese patients with fibrodysplasia ossificans progressiva

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated MEK1 binds the nuclear MyoD transcriptional complex to repress transactivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18684712

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M801681200

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18684712%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q37119764&oldid=2093301914"