(Q37119783)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22559791%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Systemically delivered insulin-like growth factor-I enhances mesenchymal stem cell-dependent fracture healing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22559791%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

mesenchymal stem cell

1 reference

1 reference

Froilán Granero Moltó

3

1 reference

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31 January 2020

Jared A. Weis

4

1 reference

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31 January 2020

author name string

Timothy J Myers

1

1 reference

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31 January 2020

Yun Yan

2

1 reference

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31 January 2020

Lara Longobardi

5

1 reference

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31 January 2020

Tieshi Li

6

1 reference

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31 January 2020

Ying Li

7

1 reference

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31 January 2020

Clara Contaldo

8

1 reference

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31 January 2020

Huseyin Ozkan

9

1 reference

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31 January 2020

Anna Spagnoli

10

1 reference

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31 January 2020

publication date

4 May 2012

1 reference

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31 January 2020

published in

Growth Factors Journal

1 reference

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31 January 2020

volume

30

1 reference

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31 January 2020

issue

4

1 reference

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31 January 2020

page(s)

230-241

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22559791%20AND%20SRC:MED&resulttype=core&format=json

Mesenchymal stem cells expressing insulin-like growth factor-I (MSCIGF) promote fracture healing and restore new bone formation in Irs1 knockout mice: analyses of MSCIGF autocrine and paracrine regenerative effects.

31 January 2020

cites work

1 reference

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Mesenchymal stem cells at the intersection of cell and gene therapy

14 September 2017

1 reference

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Efficacy of gene therapy for X-linked severe combined immunodeficiency

14 September 2017

1 reference

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A finite element inverse analysis to assess functional improvement during the fracture healing process

14 September 2017

1 reference

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Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6

14 September 2017

1 reference

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Regenerative effects of transplanted mesenchymal stem cells in fracture healing

14 September 2017

1 reference

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Repair of tissues by adult stem/progenitor cells (MSCs): controversies, myths, and changing paradigms

14 September 2017

1 reference

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Serum IGF-1 determines skeletal strength by regulating subperiosteal expansion and trait interactions

14 September 2017

1 reference

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Mesenchymal stem cells in health and disease

14 September 2017

1 reference

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Available biological treatments for complex non-unions

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Biological enhancement of tibial diaphyseal aseptic non-unions: the efficacy of autologous bone grafting, BMPs and reaming by-products

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Immunomodulatory properties of mesenchymal stromal cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Adult mesenchymal stem cells for tissue engineering versus regenerative medicine.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

New technologies for the enhancement of skeletal repair.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

The role of mesenchymal stem cells in maintenance and repair of bone

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

From the laboratory bench to the patient's bedside: an update on clinical trials with mesenchymal stem cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Clinical trials with adult stem/progenitor cells for tissue repair: let's not overlook some essential precautions

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Effects of systemic and local administration of recombinant human IGF-I (rhIGF-I) on de novo bone formation in an aged mouse model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Application of histomorphometric methods to the study of bone repair

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Cartilage disorders: potential therapeutic use of mesenchymal stem cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Genetic strategies for elucidating insulin-like growth factor action in bone

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Skeletal muscle repair by adult human mesenchymal stem cells from synovial membrane.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Circulating levels of IGF-1 directly regulate bone growth and density

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

In vitro studies of insulin-like growth factor I and bone

14 September 2017

1 reference

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Marrow stromal cells as stem cells for nonhematopoietic tissues

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Effect of insulin-like growth factor-1 on the responses to and recognition of hypoglycemia in humans. A comparison with insulin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

IGF-I secreted by osteoblasts acts as a potent chemotactic factor for osteoblasts.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Micro-computed tomography prediction of biomechanical strength in murine structural bone grafts

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Distant regulatory elements in a Sox10-beta GEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Musculoskeletal effects of the recombinant human IGF-I/IGF binding protein-3 complex in osteoporotic patients with proximal femoral fracture: a double-blind, placebo-controlled pilot study

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Enhancement of fracture-healing.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Skeletal cell fate decisions within periosteum and bone marrow during bone regeneration.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Association between insulin-like growth factor I and bone mineral density in older women and men: the Framingham Heart Study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Three year IGF-I treatment of children with Laron syndrome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

IGF-I is required for normal embryonic growth in mice

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Insulin-like growth factor-I is essential for embryonic bone development

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Percutaneous autologous bone-marrow grafting for nonunions. Influence of the number and concentration of progenitor cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Improvement of fracture healing by systemic administration of growth hormone and local application of insulin-like growth factor-1 and transforming growth factor-beta1.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Insulin-like growth factor-1 and transforming growth factor-beta1 accelerates osteotomy healing using polylactide-coated implants as a delivery system: a biomechanical and histological study in minipigs

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3752908

Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults

3 September 2018

1 reference

12 December 2020

Circulating and skeletal insulin-like growth factor-I (IGF-I) concentrations in two inbred strains of mice with different bone mineral densities

1 reference

12 December 2020

Concepts of fracture union, delayed union, and nonunion

1 reference

12 December 2020

Potential role of insulinlike growth factors in fracture healing

1 reference

12 December 2020

Long-term treatment with recombinant insulin-like growth factor (IGF)-I in children with severe IGF-I deficiency due to growth hormone insensitivity

1 reference

12 December 2020

Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation

1 reference

12 December 2020

Role of mesenchymal stem cells in regenerative medicine: application to bone and cartilage repair

1 reference

12 December 2020

In search of the in vivo identity of mesenchymal stem cells

1 reference

12 December 2020

Serum levels of insulin-like growth factor-I are positively associated with functional outcome after hip fracture in elderly women

1 reference

12 December 2020

Sleuthing the source of regeneration by MSCs

1 reference

12 December 2020

10.3109/08977194.2012.683188

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22559791%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22559791%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

PubMed publication ID

22559791

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22559791%20AND%20SRC:MED&resulttype=core&format=json