(Q37120441)

18 August 2017

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title

Delivering small interfering RNA for novel therapeutics (English)

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18 August 2017

Patrick Y Lu

1

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18 August 2017

Martin C Woodle

series ordinal

2

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18 August 2017

language of work or name

English

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publication date

1 January 2008

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Methods in Molecular Biology

18 August 2017

published in

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18 August 2017

volume

437

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18 August 2017

page(s)

93-107

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In vivo activity of nuclease-resistant siRNAs

18 August 2017

cites work

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12 December 2020

A facile nonviral method for delivering genes and siRNAs to skeletal muscle of mammalian limbs

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12 December 2020

RNA interference: from model organisms towards therapy for neural and neuromuscular disorders

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12 December 2020

Expression profiling reveals off-target gene regulation by RNAi

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Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

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12 December 2020

Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque

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12 December 2020

Inhibition of hepatitis C virus protein expression by RNA interference

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12 December 2020

Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo

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12 December 2020

Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA.

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12 December 2020

RNAi-induced gene silencing by local electroporation in targeting brain region.

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12 December 2020

Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells

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In vivo application of RNA interference: from functional genomics to therapeutics

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12 December 2020

Small interfering RNA Inhibits Hepatitis B virus replication in mice

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12 December 2020

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

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Highly branched HK peptides are effective carriers of siRNA.

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12 December 2020

RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis.

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12 December 2020

Protection against lethal influenza virus challenge by RNA interference in vivo.

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12 December 2020

Genomewide view of gene silencing by small interfering RNAs

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12 December 2020

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

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12 December 2020

siRNA relieves chronic neuropathic pain

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12 December 2020

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

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12 December 2020

SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth.

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12 December 2020

Lack of interferon response in animals to naked siRNAs

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12 December 2020

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

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12 December 2020

Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

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12 December 2020

Systemic siRNA-mediated gene silencing: a new approach to targeted therapy of cancer.

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12 December 2020

RNA interference targeting Fas protects mice from fulminant hepatitis

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12 December 2020

Harnessing in vivo siRNA delivery for drug discovery and therapeutic development

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12 December 2020

Liposomes modified with cyclic RGD peptide for tumor targeting

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12 December 2020

RNA interference in adult mice.

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12 December 2020

Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice

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12 December 2020

Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis

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12 December 2020

Inhibition of influenza virus production in virus-infected mice by RNA interference

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12 December 2020

Specificity of short interfering RNA determined through gene expression signatures

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12 December 2020

Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery.

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12 December 2020

Caspase 8 small interfering RNA prevents acute liver failure in mice

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12 December 2020

A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics

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12 December 2020

Efficient delivery of siRNA for inhibition of gene expression in postnatal mice

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12 December 2020

Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

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12 December 2020

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

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12 December 2020

Novel cationic cardiolipin analogue-based liposome for efficient DNA and small interfering RNA delivery in vitro and in vivo

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12 December 2020

Small interfering RNA targeting Raf-1 inhibits tumor growth in vitro and in vivo

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12 December 2020

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

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12 December 2020

Modulation of angiogenesis with siRNA inhibitors for novel therapeutics

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12 December 2020

Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

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12 December 2020

Attenuation of alpha2A-adrenergic receptor expression in neonatal rat brain by RNA interference or antisense oligonucleotide reduced anxiety in adulthood

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12 December 2020

Killing the messenger: short RNAs that silence gene expression

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12 December 2020

Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference

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12 December 2020

siRNA-mediated antitumorigenesis for drug target validation and therapeutics.

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12 December 2020

Lipid-mediated siRNA delivery down-regulates exogenous gene expression in the mouse brain at picomolar levels

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12 December 2020

Role of Toll-like receptors in antisense and siRNA [corrected].

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12 December 2020

Activation of the interferon system by short-interfering RNAs

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12 December 2020

Sterically stabilized polyplex: ligand-mediated activity

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12 December 2020

Gene silencing by systemic delivery of synthetic siRNAs in adult mice

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12 December 2020

10.1007/978-1-59745-210-6_3

Identifiers

DOI

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18 August 2017

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