(Q37123810)

18 August 2017

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title

Immunoregulatory T cells: role and potential as a target in malignancy (English)

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18 August 2017

2

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18 August 2017

Marc Beyer

1

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18 August 2017

publication date

1 March 2008

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18 August 2017

published in

Current Oncology Reports

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18 August 2017

volume

10

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18 August 2017

issue

2

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18 August 2017

page(s)

130-136

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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

18 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS11912-008-0021-Z

CD4+CD25+ T regulatory cells dominate multiple immune evasion mechanisms in early but not late phases of tumor development in a B cell lymphoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-008-0021-Z

Tumor-induced L-selectinhigh suppressor T cells mediate potent effector T cell blockade and cause failure of otherwise curative adoptive immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-008-0021-Z

IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-008-0021-Z

Administration of a CD25-directed immunotoxin, LMB-2, to patients with metastatic melanoma induces a selective partial reduction in regulatory T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11912-008-0021-Z

Initial depletion of regulatory T cells: the missing solution to preserve the immune functions of T lymphocytes designed for cell therapy

21 January 2018

1 reference

12 December 2020

IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

1 reference

12 December 2020

Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells

1 reference

12 December 2020

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

1 reference

12 December 2020

Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine

1 reference

12 December 2020

The CCR4 as a novel-specific molecular target for immunotherapy in Hodgkin lymphoma

1 reference

12 December 2020

Inability to mediate prolonged reduction of regulatory T Cells after transfer of autologous CD25-depleted PBMC and interleukin-2 after lymphodepleting chemotherapy

1 reference

12 December 2020

Regulatory T cells in cancer

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12 December 2020

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

1 reference

12 December 2020

Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors

1 reference

12 December 2020

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

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12 December 2020

Specific recruitment of CC chemokine receptor 4-positive regulatory T cells in Hodgkin lymphoma fosters immune privilege

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12 December 2020

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

1 reference

12 December 2020

IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity

1 reference

12 December 2020

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

1 reference

12 December 2020

Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma

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12 December 2020

Autologous melanoma-induced activation of regulatory T cells that suppress cytotoxic response

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12 December 2020

Foxp3-dependent programme of regulatory T-cell differentiation

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12 December 2020

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

1 reference

12 December 2020

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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12 December 2020

Vaccination against the Forkhead Family Transcription Factor Foxp3 Enhances Tumor Immunity

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12 December 2020

Tumor-induced expansion of regulatory T cells by conversion of CD4+CD25- lymphocytes is thymus and proliferation independent

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12 December 2020

CD4+CD25highFOXP3+ regulatory T cells in peripheral blood are primarily of effector memory phenotype.

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12 December 2020

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

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12 December 2020

Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients

1 reference

12 December 2020

Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity

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12 December 2020

Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.

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12 December 2020

CCR4 as a novel molecular target for immunotherapy of cancer

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12 December 2020

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

1 reference

12 December 2020

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

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12 December 2020

In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myeloma.

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12 December 2020

Depletion of CD4+CD25+ human regulatory T cells in vivo: kinetics of Treg depletion and alterations in immune functions in vivo and in vitro

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12 December 2020

Dendritic cells loaded with stressed tumor cells elicit long-lasting protective tumor immunity in mice depleted of CD4+CD25+ regulatory T cells

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12 December 2020

CD25+ CD4+ regulatory T-cells in cancer

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12 December 2020

Inability of a fusion protein of IL-2 and diphtheria toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma

1 reference

12 December 2020

CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo

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12 December 2020

Depletion of T(reg) cells inhibits minimal residual disease after surgery of HPV16-associated tumours

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12 December 2020

Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma

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12 December 2020

A peripheral circulating compartment of natural naive CD4 Tregs

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12 December 2020

Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.

1 reference

12 December 2020

Depletion of CD4+ CD25+ regulatory cells augments the generation of specific immune T cells in tumor-draining lymph nodes

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12 December 2020

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

1 reference

12 December 2020

Large-scale depletion of CD25+ regulatory T cells from patient leukapheresis samples

1 reference

12 December 2020

T-cell-mediated suppression of anti-tumor immunity. An explanation for progressive growth of an immunogenic tumor

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12 December 2020

Selective elimination of human regulatory T lymphocytes in vitro with the recombinant immunotoxin LMB-2.

1 reference

12 December 2020

10.1007/S11912-008-0021-Z

Identifiers

DOI

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18 August 2017

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