(Q37129806)

18 August 2017

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title

Foxo in the immune system (English)

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18 August 2017

S L Peng

1

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18 August 2017

language of work or name

English

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publication date

1 April 2008

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18 August 2017

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18 August 2017

volume

27

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18 August 2017

issue

16

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18 August 2017

page(s)

2337-2344

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https://scigraph.springernature.com/pub.10.1038/onc.2008.26

18 August 2017

exact match

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cites work

Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

GILZ, a new target for the transcription factor FoxO3, protects T lymphocytes from interleukin-2 withdrawal-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Mechanisms of disease: Transcription factors in inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Cytokine-mediated FOXO3a phosphorylation suppresses FasL expression in hemopoietic cell lines: investigations of the role of Fas in apoptosis due to cytokine starvation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

FOXO3a induces differentiation of Bcr-Abl-transformed cells through transcriptional down-regulation of Id1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Vav1 promotes T cell cycle progression by linking TCR/CD28 costimulation to FOXO1 and p27kip1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

FOXO transcription factors cooperate with delta EF1 to activate growth suppressive genes in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Forkhead-box transcription factors and their role in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Neutrophil activation by fMLP regulates FOXO (forkhead) transcription factors by multiple pathways, one of which includes the binding of FOXO to the survival factor Mcl-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Regulation of the Forkhead transcription factor AFX by Ral-dependent phosphorylation of threonines 447 and 451

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

CTLA-4-Ig activates forkhead transcription factors and protects dendritic cells from oxidative stress in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

C5b-9-induced endothelial cell proliferation and migration are dependent on Akt inactivation of forkhead transcription factor FOXO1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

B cell receptor signaling down-regulates forkhead box transcription factor class O 1 mRNA expression via phosphatidylinositol 3-kinase and Bruton's tyrosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Skp2 inhibits FOXO1 in tumor suppression through ubiquitin-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Growth, differentiation, and malignant transformation of pre-B cells mediated by inducible activation of v-Abl oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Forkhead transcription factors in immunology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

FOXO transcription factors: key regulators of cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Inhibition of forkhead box class O family member transcription factors in rheumatoid synovial tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

CD152 (CTLA-4) determines the unequal resistance of Th1 and Th2 cells against activation-induced cell death by a mechanism requiring PI3 kinase function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Immune regulation by Foxo transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Akt activation promotes degradation of tuberin and FOXO3a via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Phosphoinositide 3-kinase signalling and FoxO transcription factors in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

The psammaplysenes, specific inhibitors of FOXO1a nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Common mechanism for oncogenic activation of MLL by forkhead family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Discovery of nonpeptidic small-molecule AP-1 inhibitors: lead hopping based on a three-dimensional pharmacophore model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Regulation of FoxO activity by CBP/p300-mediated acetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

FOXO4 transcriptional activity is regulated by monoubiquitination and USP7/HAUSP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

In control of biology: of mice, men and Foxes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

RUNX3 cooperates with FoxO3a to induce apoptosis in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Involvement of phosphatidylinositol 3-kinase gamma in neutrophil apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth, and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

The induction of Bim expression in human T-cell blasts is dependent on nonapoptotic Fas/CD95 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Stable activation of phosphatidylinositol 3-kinase in the T cell immunological synapse stimulates Akt signaling to FoxO1 nuclear exclusion and cell growth control

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

The negative regulators Foxj1 and Foxo3a are up-regulated by a peptide that inhibits systemic lupus erythematosus-associated T cell responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.26

31 March 2020

Identifiers

DOI

10.1038/ONC.2008.26

1 reference

18 August 2017

1 reference