(Q37139621)

English

A myosin activator improves actin assembly and sarcomere function of human-induced pluripotent stem cell-derived cardiomyocytes with a troponin T point mutation

scientific article published on 06 May 2016

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

A myosin activator improves actin assembly and sarcomere function of human-induced pluripotent stem cell-derived cardiomyocytes with a troponin T point mutation (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Human Induced Pluripotent Stem Cells

1 reference

based on heuristic

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author name string

K M Broughton

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

J Li

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

E Sarmah

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

C M Warren

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Y-H Lin

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

M P Henze

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

V Sanchez-Freire

7

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

R J Solaro

8

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

B Russell

9

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

1 reference

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publication date

6 May 2016

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Europe PubMed Central

PMC publication ID

18 August 2017

American Journal of Physiology Heart and Circulatory Physiology

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Europe PubMed Central

PMC publication ID

18 August 2017

311

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

H107-17

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4967204/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy.

1 reference

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14 September 2017

Omecamtiv Mecarbil, a Cardiac Myosin Activator, Increases Ca2+ Sensitivity in Myofilaments With a Dilated Cardiomyopathy Mutant Tropomyosin E54K.

1 reference

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Modeling Cardiovascular Diseases with Patient-Specific Human Pluripotent Stem Cell-Derived Cardiomyocytes

1 reference

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Cardiomyocyte subdomain contractility arising from microenvironmental stiffness and topography

1 reference

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Actin dynamics is rapidly regulated by the PTEN and PIP2 signaling pathways leading to myocyte hypertrophy

1 reference

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Whole exome sequencing identifies a troponin T mutation hot spot in familial dilated cardiomyopathy

1 reference

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Phosphatidylinositol 4,5-bisphosphate regulates CapZβ1 and actin dynamics in response to mechanical strain

1 reference

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Bioprocessing of cryopreservation for large-scale banking of human pluripotent stem cells

1 reference

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14 September 2017

CapZ and actin capping dynamics increase in myocytes after a bout of exercise and abates in hours after stimulation ends

1 reference

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1 reference

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Cardiomyocytes from late embryos and neonates do optimal work and striate best on substrates with tissue-level elasticity: metrics and mathematics

1 reference

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14 September 2017

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy.

1 reference

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14 September 2017

Microdomain heterogeneity in 3D affects the mechanics of neonatal cardiac myocyte contraction.

1 reference

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14 September 2017

A model of calcium activation of the cardiac thin filament

1 reference

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14 September 2017

Cardiac myosin activation: a potential therapeutic approach for systolic heart failure

1 reference

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14 September 2017

Troponin T is essential for sarcomere assembly in zebrafish skeletal muscle.

1 reference

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14 September 2017

Improvement of cardiac function by a cardiac Myosin activator in conscious dogs with systolic heart failure

1 reference

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Mechanical stress-induced sarcomere assembly for cardiac muscle growth in length and width

1 reference

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Evolution of scar structure, mechanics, and ventricular function after myocardial infarction in the rat.

1 reference

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Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy

1 reference

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14 September 2017

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

1 reference

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14 September 2017

Substrate stiffness affects the functional maturation of neonatal rat ventricular myocytes

1 reference

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14 September 2017

Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T

1 reference

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14 September 2017

Dilated cardiomyopathy mutant tropomyosin mice develop cardiac dysfunction with significantly decreased fractional shortening and myofilament calcium sensitivity

1 reference

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Tissue cells feel and respond to the stiffness of their substrate

1 reference

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14 September 2017

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1 reference

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Impact of beta-myosin heavy chain isoform expression on cross-bridge cycling kinetics

1 reference

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14 September 2017

The troponin tail domain promotes a conformational state of the thin filament that suppresses myosin activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4967204

14 September 2017

Ca(2+)-desensitizing effect of a deletion mutation Delta K210 in cardiac troponin T that causes familial dilated cardiomyopathy.

1 reference

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MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure

1 reference

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Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle

1 reference

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Contractile properties of developing human fetal cardiac muscle.

1 reference

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3 September 2018

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1 reference

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Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance.

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Protection against endotoxemia-induced contractile dysfunction in mice with cardiac-specific expression of slow skeletal troponin I.

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3 September 2018

Cardiac troponin T isoforms affect the Ca(2+) sensitivity of force development in the presence of slow skeletal troponin I: insights into the role of troponin T isoforms in the fetal heart.

1 reference

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Method for cardiac myosin heavy chain separation by sodium dodecyl sulfate gel electrophoresis

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Expression of slow skeletal troponin I in hearts of phospholamban knockout mice alters the relaxant effect of beta-adrenergic stimulation

1 reference

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3 September 2018

Differential expression of TnI and TnT isoforms in rabbit heart during the perinatal period and during cardiovascular stress.

1 reference

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3 September 2018

Factors affecting polyacrylamide gel electrophoresis and electroblotting of high-molecular-weight myofibrillar proteins

1 reference

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3 September 2018

Guidelines for reporting statistics in journals published by the American Physiological Society

1 reference

https://api.crossref.org/works/10.1152%2FAJPHEART.00162.2016

21 January 2018

Electrophoretic separation and quantitation of cardiac myosin heavy chain isoforms in eight mammalian species

1 reference

https://pubmed.ncbi.nlm.nih.gov/27199119

12 December 2020

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Why we need to understand the mechanics of developing cardiac sarcomeres in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/27199119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guidelines for reporting statistics in journals published by the American Physiological Society: the sequel

1 reference

https://pubmed.ncbi.nlm.nih.gov/27199119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased Ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin I

1 reference

https://pubmed.ncbi.nlm.nih.gov/27199119

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based on heuristic

inferred from PubMed ID database lookup

Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/27199119

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based on heuristic

inferred from PubMed ID database lookup

Transverse elasticity of myofibrils of rabbit skeletal muscle studied by atomic force microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/27199119

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based on heuristic

inferred from PubMed ID database lookup

Microtextured substrata alter gene expression, protein localization and the shape of cardiac myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27199119

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based on heuristic

inferred from PubMed ID database lookup

Actin dynamics: tropomyosin provides stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/27199119

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPHEART.00162.2016

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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