(Q37149839)

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Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet Syndrome

scientific article published on 13 May 2016

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet Syndrome (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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haploinsufficiency

0 references

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

J Hsiao

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

T Y Yuan

2

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Europe PubMed Central

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18 August 2017

M S Tsai

3

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Europe PubMed Central

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18 August 2017

C Y Lu

4

1 reference

Europe PubMed Central

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18 August 2017

Y C Lin

5

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Europe PubMed Central

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18 August 2017

M L Lee

6

1 reference

Europe PubMed Central

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18 August 2017

S W Lin

7

1 reference

Europe PubMed Central

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18 August 2017

F C Chang

8

1 reference

Europe PubMed Central

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18 August 2017

H Liu Pimentel

9

1 reference

Europe PubMed Central

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18 August 2017

C Olive

10

1 reference

Europe PubMed Central

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18 August 2017

C Coito

11

1 reference

Europe PubMed Central

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18 August 2017

G Shen

12

1 reference

Europe PubMed Central

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18 August 2017

M Young

13

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Europe PubMed Central

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18 August 2017

T Thorne

14

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Europe PubMed Central

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18 August 2017

M Lawrence

15

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Europe PubMed Central

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18 August 2017

M Magistri

16

1 reference

Europe PubMed Central

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18 August 2017

M A Faghihi

17

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Europe PubMed Central

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18 August 2017

O Khorkova

18

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Europe PubMed Central

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18 August 2017

C Wahlestedt

19

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18 August 2017

publication date

13 May 2016

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Europe PubMed Central

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18 August 2017

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Europe PubMed Central

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18 August 2017

9

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18 August 2017

257-277

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18 August 2017

Cognitive Deficits Associated with Nav1.1 Alterations: Involvement of Neuronal Firing Dynamics and Oscillations

1 reference

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Antisense RNA controls LRP1 Sense transcript expression through interaction with a chromatin-associated protein, HMGB2

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6 September 2017

Long noncoding RNAs: a potent source of regulation in immunity and disease

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Towards a therapy for Angelman syndrome by targeting a long non-coding RNA.

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Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome

1 reference

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6 September 2017

Non-coding RNAs as direct and indirect modulators of epigenetic regulation

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Strain- and age-dependent hippocampal neuron sodium currents correlate with epilepsy severity in Dravet syndrome mice

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Regulation of the apolipoprotein gene cluster by a long noncoding RNA

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6 September 2017

Encephalopathy in children with Dravet syndrome is not a pure consequence of epilepsy

1 reference

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Nuclear lncRNAs as epigenetic regulators-beyond skepticism

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Promiscuous RNA binding by Polycomb repressive complex 2.

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Promoter RNA links transcriptional regulation of inflammatory pathway genes

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6 September 2017

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome

1 reference

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6 September 2017

Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome.

1 reference

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6 September 2017

Targeting long non-coding RNA to therapeutically upregulate gene expression

1 reference

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6 September 2017

Sudden unexpected death in a mouse model of Dravet syndrome

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6 September 2017

Focal Scn1a knockdown induces cognitive impairment without seizures

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A call for transparent reporting to optimize the predictive value of preclinical research

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6 September 2017

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy

1 reference

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6 September 2017

The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression

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6 September 2017

Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4972487

6 September 2017

Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts

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6 September 2017

Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation.

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6 September 2017

Pure haploinsufficiency for Dravet syndrome Na(V)1.1 (SCN1A) sodium channel truncating mutations

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6 September 2017

A natural antisense transcript at the Huntington's disease repeat locus regulates HTT expression

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6 September 2017

Molecular and cellular basis: insights from experimental models of Dravet syndrome

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6 September 2017

Insights into pathophysiology and therapy from a mouse model of Dravet syndrome

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6 September 2017

The core Dravet syndrome phenotype

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6 September 2017

Genome-wide identification of polycomb-associated RNAs by RIP-seq

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Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene

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6 September 2017

Altered function of the SCN1A voltage-gated sodium channel leads to gamma-aminobutyric acid-ergic (GABAergic) interneuron abnormalities

1 reference

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6 September 2017

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

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The Vienna RNA websuite

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Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation

1 reference

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Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

1 reference

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Single-channel properties of human NaV1.1 and mechanism of channel dysfunction in SCN1A-associated epilepsy

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Severe myoclonic epilepsy of infants (Dravet syndrome): natural history and neuropsychological findings.

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12 December 2020

based on heuristic

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Identifiers

10.1016/J.EBIOM.2016.05.011

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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