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Phosphorylation switches the general splicing repressor SRp38 to a sequence-specific activator.
scientific article published on 14 September 2008
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Europe PubMed Central
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2668916
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794844%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
title
Phosphorylation switches the general splicing repressor SRp38 to a sequence-specific activator
(English)
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Europe PubMed Central
PMCID
2668916
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794844%20AND%20SRC:MED&resulttype=core&format=json
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14 January 2020
main subject
phosphorylation
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author
James L. Manley
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3
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Europe PubMed Central
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2668916
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794844%20AND%20SRC:MED&resulttype=core&format=json
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14 January 2020
author name string
Ying Feng
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1
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Europe PubMed Central
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2668916
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794844%20AND%20SRC:MED&resulttype=core&format=json
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14 January 2020
Mo Chen
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2
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2668916
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794844%20AND%20SRC:MED&resulttype=core&format=json
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14 January 2020
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English
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14 September 2008
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retrieved
14 January 2020
published in
Nature Structural & Molecular Biology
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2668916
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794844%20AND%20SRC:MED&resulttype=core&format=json
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14 January 2020
volume
15
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14 January 2020
page(s)
1040-1048
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2668916
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14 January 2020
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10
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14 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/nsmb.1485
0 references
cites work
The search for alternative splicing regulators: new approaches offer a path to a splicing code
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Regulation of alternative splicing by reversible protein phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Comparative analysis identifies exonic splicing regulatory sequences--The complex definition of enhancers and silencers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Distribution of SR protein exonic splicing enhancer motifs in human protein-coding genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Multiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Understanding alternative splicing: towards a cellular code
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
RS domains contact the pre-mRNA throughout spliceosome assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Regulation of alternative RNA splicing by exon definition and exon sequences in viral and mammalian gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Pre-mRNA splicing: awash in a sea of proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
The SR protein SRp38 represses splicing in M phase cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Mutant loxP vectors for selectable marker recycle and conditional knock-outs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Pre-mRNA splicing in the new millennium
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
SR proteins Asf/SF2 and 9G8 interact to activate enhancer-dependent intron D splicing of bovine growth hormone pre-mRNA in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Protein diversity from alternative splicing: a challenge for bioinformatics and post-genome biology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Sorting out the complexity of SR protein functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Alternative pre-mRNA splicing: the logic of combinatorial control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Cloning and characterization of two neural-salient serine/arginine-rich (NSSR) proteins involved in the regulation of alternative splicing in neurones.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Resolution of the mammalian E complex and the ATP-dependent spliceosomal complexes on native agarose mini-gels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
The protein kinase Clk/Sty directly modulates SR protein activity: both hyper- and hypophosphorylation inhibit splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
The SRm160/300 splicing coactivator is required for exon-enhancer function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Enhancer elements activate the weak 3' splice site of alpha-tropomyosin exon 2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Phosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: creation of an SRp40-specific splicing enhancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
SR proteins and splicing control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Polypurine sequences within a downstream exon function as a splicing enhancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Specific interactions between proteins implicated in splice site selection and regulated alternative splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Modulation of 5' splice site choice in pre-messenger RNA by two distinct steps
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Intrinsic U2AF binding is modulated by exon enhancer signals in parallel with changes in splicing activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
6 September 2017
A complex signaling pathway regulates SRp38 phosphorylation and pre-mRNA splicing in response to heat shock
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
14 September 2017
Arginine/serine-rich domains of SR proteins can function as activators of pre-mRNA splicing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
27 June 2018
Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
27 June 2018
ASF/SF2 and SC35 regulate the glutamate receptor subunit 2 alternative flip/flop splicing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
3 September 2018
Tra2betal regulates P19 neuronal differentiation and the splicing of FGF-2R and GluR-B minigenes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
3 September 2018
Arginine-serine-rich domains bound at splicing enhancers contact the branchpoint to promote prespliceosome assembly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
3 September 2018
Distinct factor requirements for exonic splicing enhancer function and binding of U2AF to the polypyrimidine tract.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
3 September 2018
Functions of SR and Tra2 proteins in pre-mRNA splicing regulation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
3 September 2018
Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
3 September 2018
The Sex-lethal amino terminus mediates cooperative interactions in RNA binding and is essential for splicing regulation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
3 September 2018
SR proteins escort the U4/U6.U5 tri-snRNP to the spliceosome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668916
retrieved
3 September 2018
A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNSMB.1485
retrieved
31 March 2020
Modification of a PCR-based site-directed mutagenesis method
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNSMB.1485
retrieved
31 March 2020
Identifiers
DOI
10.1038/NSMB.1485
1 reference
stated in
Europe PubMed Central
PMCID
2668916
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794844%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
PMCID
2668916
1 reference
stated in
Europe PubMed Central
PMCID
2668916
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794844%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
PubMed ID
18794844
1 reference
stated in
Europe PubMed Central
PMCID
2668916
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18794844%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
ResearchGate publication ID
23260320
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