(Q37162535)

18 August 2017

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title

Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma (English)

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18 August 2017

Peter Hersey

1

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18 August 2017

Xu Dong Zhang

series ordinal

2

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18 August 2017

publication date

1 June 2008

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Pigment Cell & Melanoma Research

18 August 2017

published in

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18 August 2017

volume

21

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18 August 2017

issue

3

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18 August 2017

page(s)

358-367

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ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

18 August 2017

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Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species.

21 January 2018

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The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

21 January 2018

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Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

21 January 2018

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Examination of mutations in BRAF, NRAS, and PTEN in primary cutaneous melanoma.

21 January 2018

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Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death

21 January 2018

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Role of the unfolded protein response in cell death

21 January 2018

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Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

21 January 2018

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Targeting XBP-1 as a novel anti-cancer strategy.

21 January 2018

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JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

21 January 2018

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Stress induction of GRP78/BiP and its role in cancer.

21 January 2018

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Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53

21 January 2018

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Lysosomes and endoplasmic reticulum: targets for improved, selective anticancer therapy

21 January 2018

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Transcriptional upregulation of PUMA modulates endoplasmic reticulum calcium pool depletion-induced apoptosis via Bax activation

21 January 2018

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Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling

21 January 2018

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21 January 2018

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21 January 2018

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Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

21 January 2018

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21 January 2018

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ER stress triggers apoptosis by activating BH3-only protein Bim

21 January 2018

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Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta

21 January 2018

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Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

21 January 2018

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Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation

21 January 2018

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Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

21 January 2018

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Functional and therapeutic significance of Akt deregulation in malignant melanoma.

21 January 2018

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Curcumin-induced GADD153 upregulation: modulation by glutathione

21 January 2018

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Tunicamycin enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human prostate cancer cells

21 January 2018

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An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells

21 January 2018

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Mediators of endoplasmic reticulum stress-induced apoptosis

21 January 2018

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Management of cutaneous melanoma

21 January 2018

1 reference

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A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.

21 January 2018

1 reference

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2008.00467.X

From acute ER stress to physiological roles of the Unfolded Protein Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2008.00467.X

10.1111/J.1755-148X.2008.00467.X

21 January 2018

Identifiers

DOI

1 reference

18 August 2017

1 reference