(Q37164698)

18 August 2017

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title

PE2I: a radiopharmaceutical for in vivo exploration of the dopamine transporter (English)

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18 August 2017

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Patrick Emond

1

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18 August 2017

Denis Guilloteau

series ordinal

2

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18 August 2017

Sylvie Chalon

series ordinal

3

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18 August 2017

language of work or name

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1 January 2008

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CNS Neuroscience & Therapeutics

18 August 2017

published in

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18 August 2017

volume

14

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18 August 2017

issue

1

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18 August 2017

page(s)

47-64

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Simplified reference region model for the kinetic analysis of [99mTc]TRODAT-1 binding to dopamine transporters in nonhuman primates using single-photon emission tomography.

18 August 2017

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21 January 2018

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New, potent cocaine analogs: ligand binding and transport studies in rat striatum

21 January 2018

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[125I]RTI-55: a potent ligand for dopamine transporters

21 January 2018

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High-affinity binding of [125I]RTI-55 to dopamine and serotonin transporters in rat brain

21 January 2018

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Toward a pathophysiology of attention-deficit/hyperactivity disorder

21 January 2018

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Impact of dopamine transporter SPECT using 123I-Ioflupane on diagnosis and management of patients with clinically uncertain Parkinsonian syndromes

21 January 2018

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Time course of changes in striatal dopamine transporters and D2 receptors with specific iodinated markers in a rat model of Parkinson's disease.

21 January 2018

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Pharmacological characterization of (E)-N-(4-fluorobut-2-enyl)-2beta-carbomethoxy-3beta-(4'-tolyl)nortropane (LBT-999) as a highly promising fluorinated ligand for the dopamine transporter

21 January 2018

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Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET.

21 January 2018

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Dopamine transporter density in patients with attention deficit hyperactivity disorder.

21 January 2018

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Attention deficit hyperactivity disorder: binding of [99mTc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment.

21 January 2018

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Interference of anaesthetics with radioligand binding in neuroreceptor studies

21 January 2018

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Synthesis and ligand binding of nortropane derivatives: N-substituted 2beta-carbomethoxy-3beta-(4'-iodophenyl)nortropane and N-(3-iodoprop-(2E)-enyl)-2beta-carbomethoxy-3beta-(3',4'-disubstituted phenyl)nortropane. New high-affinity and selective co

21 January 2018

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21 January 2018

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Protection of dopaminergic nigrostriatal afferents by GDNF delivered by microspheres in a rodent model of Parkinson's disease

21 January 2018

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Exploration of the dopamine transporter: in vitro and in vivo characterization of a high-affinity and high-specificity iodinated tropane derivative (E)-N-(3-iodoprop-2-enyl)-2beta-carbomethoxy-3beta-(4'-m ethylph enyl)nortropane (PE2I).

21 January 2018

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Whole hemisphere autoradiography of the postmortem human brain.

21 January 2018

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Visualization of the dopamine transporter in the human brain postmortem with the new selective ligand [125I]PE2I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

[(11)C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

[11C]beta-CIT-FE, a radioligand for quantitation of the dopamine transporter in the living brain using positron emission tomography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Correlation between quantitative imaging and behavior in unilaterally 6-OHDA-lesioned rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

In vivo PET measurements with [11C]PE2I to evaluate fetal mesencephalic transplantations to unilateral 6-OHDA-lesioned rats

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease

21 January 2018

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Characterization of sodium-dependent [3H]GBR-12935 binding in brain: a radioligand for selective labelling of the dopamine transport complex.

21 January 2018

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Reduced midbrain dopamine transporter binding in male adolescents with attention-deficit/hyperactivity disorder: association between striatal dopamine markers and motor hyperactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Quantitative analyses of regional [11C]PE2I binding to the dopamine transporter in the human brain: a PET study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging.

21 January 2018

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IPT: a novel iodinated ligand for the CNS dopamine transporter.

21 January 2018

1 reference

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Graphical, kinetic, and equilibrium analyses of in vivo [123I] beta-CIT binding to dopamine transporters in healthy human subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Assessment of 11C-PE2I binding to the neuronal dopamine transporter in humans with the high-spatial-resolution PET scanner HRRT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

[18F] beta-CIT-FP is superior to [11C] beta-CIT-FP for quantitation of the dopamine transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson's disease

21 January 2018

1 reference

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How valid is dopamine transporter imaging as a surrogate marker in research trials in Parkinson's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Pharmacological characterisation of (E)-N-(3-iodoprop-2-enyl)-2beta-carbomethoxy-3beta-(4'-methylphenyl)nortropane (PE2I) binding to the rat neuronal dopamine transporter expressed in COS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Quantification of [(123)I]PE2I binding to dopamine transporters with SPET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Progression of dopaminergic degeneration in Parkinson's disease and atypical parkinsonism: a longitudinal beta-CIT SPECT study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Anatomic and biochemical correlates of the dopamine transporter ligand 11C-PE2I in normal and parkinsonian primates: comparison with 6-[18F]fluoro-L-dopa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Presymptomatic diagnosis of experimental Parkinsonism with 123I-PE2I SPECT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Whole-body distribution and radiation dosimetry of the dopamine transporter radioligand [(11)C]PE2I in healthy volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

[11C]LBT-999: a suitable radioligand for investigation of extra-striatal dopamine transporter with PET.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Slow isomerization step in the interaction between mouse dopamine transporter and dopamine re-uptake inhibitor N-(3-iodoprop-2E-enyl)-2beta-carbo-[3H]methoxy-3beta-(4'-methylphenyl)nortropane.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Synthesis of 3H-labeled N-(3-iodoprop-2E-enyl)-2beta-carbomethoxy-3beta-(4-methylphenyl)nortropane (PE2I) and its interaction with mice striatal membrane fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

21 January 2018

Dopamine genes and ADHD.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Measurement of the striatal dopamine transporter density and heterogeneity in type 1 alcoholics using human whole hemisphere autoradiography

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Different effect of age on dopamine transporters in the dorsal and ventral striatum of controls and alcoholics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Visualization of the cortical dopamine transporter in type 1 and 2 alcoholics with human whole hemisphere autoradiography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Dopamine transporter messenger RNA in Parkinson's disease and control substantia nigra neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Unaltered dopamine transporter availability in adult attention deficit hyperactivity disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Reproducibility of [123I]PE2I binding to dopamine transporters with SPECT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

SPECT imaging of dopamine and serotonin transporters with [123I]?-CIT. Binding kinetics in the human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-5949.2007.00033.X

Pharmacological characterization of (E)-N-(3-iodoprop-2-enyl)-2beta-carbomethoxy-3beta-(4'-methylphenyl)n ortropane as a selective and potent inhibitor of the neuronal dopamine transporter

21 January 2018

1 reference

12 December 2020

Role of high-affinity receptors and membrane transporters in nonsynaptic communication and drug action in the central nervous system

1 reference

12 December 2020

Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography

1 reference

12 December 2020

Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT SPECT imaging: the [123I]-FP-CIT study group

1 reference

12 December 2020

Determination of dissociation constants and specific rate constants of enzyme-substrate (or protein-ligand) interactions from rapid reaction kinetic data

1 reference

12 December 2020

Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease.

1 reference

12 December 2020

Quantification of dopamine transporter by 123I-PE2I SPECT and the noninvasive Logan graphical method in Parkinson's disease

1 reference

12 December 2020

A simple synthesis of [11C]methyl triflate

1 reference

12 December 2020

Quantification of 123I-PE2I binding to dopamine transporter with SPECT after bolus and bolus/infusion.

1 reference

12 December 2020

PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements.

1 reference

12 December 2020

Cocaine receptors labeled by [3H]2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane.

1 reference

12 December 2020

Neuropharmacological basis of stimulant drug action in attention deficit disorder with hyperactivity: a review and synthesis.

1 reference

12 December 2020

The dopamine transporter: immunochemical characterization and localization in brain

1 reference

12 December 2020

Characterization of a recombinant human dopamine transporter in multiple cell lines

1 reference

12 December 2020

Association of attention-deficit disorder and the dopamine transporter gene.

1 reference

12 December 2020

Binding of the cocaine analog 2 beta-carbomethoxy-3 beta-(4-[125I]iodophenyl)tropane to serotonin and dopamine transporters: different ionic requirements for substrate and 2 beta-carbomethoxy-3 beta-(4-[125I]iodophenyl)tropane binding.

1 reference

12 December 2020

Imaging of dopamine transporters with iodine-123-beta-CIT and SPECT in Parkinson's disease.

1 reference

12 December 2020

Confirmation of association between attention deficit hyperactivity disorder and a dopamine transporter polymorphism

1 reference

12 December 2020

Test/retest reproducibility of iodine-123-betaCIT SPECT brain measurement of dopamine transporters in Parkinson's patients.

1 reference

12 December 2020

Anti-hyperactivity medication: methylphenidate and amphetamine

1 reference

12 December 2020

Imaging of dopamine transporters with iodine-123-FP-CIT SPECT in healthy controls and patients with Parkinson's disease.

1 reference

12 December 2020

10.1111/J.1755-5949.2007.00033.X

Identifiers

DOI

1 reference

18 August 2017

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