(Q37170109)

English

Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation

scientific article published on February 2009

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Statements

scholarly article

1 reference

Europe PubMed Central

18 August 2017

Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation (English)

1 reference

Europe PubMed Central

18 August 2017

0 references

toll-like receptor

0 references

1 reference

based on heuristic

inferred from title

author name string

Devadoss J Samuvel

1

1 reference

Europe PubMed Central

18 August 2017

Kamala P Sundararaj

2

1 reference

Europe PubMed Central

18 August 2017

Alena Nareika

3

1 reference

Europe PubMed Central

18 August 2017

Maria F Lopes-Virella

4

1 reference

Europe PubMed Central

18 August 2017

Yan Huang

5

1 reference

Europe PubMed Central

18 August 2017

language of work or name

0 references

publication date

1 February 2009

1 reference

Europe PubMed Central

18 August 2017

Journal of Immunology

1 reference

Europe PubMed Central

18 August 2017

182

1 reference

Europe PubMed Central

18 August 2017

4

1 reference

Europe PubMed Central

18 August 2017

2476-2484

1 reference

Europe PubMed Central

18 August 2017

The macrophage-inducible C-type lectin, mincle, is an essential component of the innate immune response to Candida albicans

1 reference

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Antioxidants: do they have a role in the treatment of insulin resistance?

1 reference

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Metabolic remodeling of malignant gliomas for enhanced sensitization during radiotherapy: an in vitro study

1 reference

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6 September 2017

TLR4 links innate immunity and fatty acid-induced insulin resistance

1 reference

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6 September 2017

Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins.

1 reference

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6 September 2017

Lactate--a signal coordinating cell and systemic function

1 reference

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Role of cAMP response element binding protein in cardiovascular remodeling: good, bad, or both?

1 reference

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6 September 2017

Endotoxin recognition molecules, Toll-like receptor 4-MD-2.

1 reference

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6 September 2017

Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity- and diet-induced insulin resistance

1 reference

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6 September 2017

The SLC16 gene family?from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673542

6 September 2017

Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673542

6 September 2017

Bench-to-bedside review: lactate and the lung

1 reference

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Inhibition of cyclooxygenase-1 or -2 on insulin sensitivity in healthy subjects

1 reference

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The role of cyclooxygenases in inflammation, cancer, and development

1 reference

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6 September 2017

The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673542

6 September 2017

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673542

6 September 2017

Short-chain carboxylic-acid-stimulated, PMN-mediated gingival inflammation

1 reference

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Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins

1 reference

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Risk factors for type 2 (non-insulin-dependent) diabetes mellitus. Thirteen and one-half years of follow-up of the participants in a study of Swedish men born in 1913.

1 reference

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Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE

1 reference

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Interleukin-8, a chemotactic and inflammatory cytokine

1 reference

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6 September 2017

Lactate production in adipose tissue: a regulated function with extra-adipose implications

1 reference

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6 September 2017

Establishment and characterization of a human histiocytic lymphoma cell line (U-937)

1 reference

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Lactate sensitive transcription factor network in L6 cells: activation of MCT1 and mitochondrial biogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673542

14 September 2017

Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673542

14 September 2017

Macrophage-secreted factors induce adipocyte inflammation and insulin resistance

1 reference

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Lipopolysaccharide-mediated reactive oxygen species and signal transduction in the regulation of interleukin-1 gene expression

1 reference

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28 September 2017

Expression of the lactate transporter MCT1 in macrophages

1 reference

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Anaerobic metabolism and wound healing: An hypothesis for the initiation and cessation of collagen synthesis in wounds

1 reference

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Lactic acidosis increases tumor necrosis factor secretion and transcription in vitro

1 reference

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Regulation of T-cell functions by L-lactate.

1 reference

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Lactate treatment causes NF-kappaB activation and CD44 shedding in cultured trabecular meshwork cells.

1 reference

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Lactate stimulates endothelial cell migration.

1 reference

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Effect of enhanced prostacyclin synthesis by adenovirus-mediated transfer on lipopolysaccharide stimulation in neuron-glia cultures

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Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B.

1 reference

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Retinal function loss after monocarboxylate transport inhibition

1 reference

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1 reference

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Essential role of MD-2 in LPS responsiveness and TLR4 distribution.

1 reference

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1 reference

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1 reference

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Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201903

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L(+)-lactate transport in perfused rat skeletal muscle: kinetic characteristics and sensitivity to pH and transport inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201903

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of interleukin 2 production, interleukin 2 mRNA expression and intracellular glutathione levels in ex vivo derived T lymphocytes by lactate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201903

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of hyperlactatemia without acidosis during hypermetabolic stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201903

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperlactatemia reduces muscle glucose uptake and GLUT-4 mRNA while increasing (E1alpha)PDH gene expression in rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/19201903

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.0802059

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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