(Q37170955)

18 August 2017

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title

The role of serpins in vertebrate immunity (English)

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18 August 2017

M S J Mangan

1

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18 August 2017

D Kaiserman

series ordinal

2

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18 August 2017

P I Bird

series ordinal

3

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18 August 2017

publication date

20 May 2008

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18 August 2017

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18 August 2017

volume

72

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18 August 2017

issue

1

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18 August 2017

page(s)

1-10

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Tip of another iceberg: Drosophila serpins

18 August 2017

cites work

1 reference

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Innate immune responses of a lepidopteran insect, Manduca sexta

21 January 2018

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The baculovirus p35 protein inhibits Fas- and tumor necrosis factor-induced apoptosis.

21 January 2018

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Elastase inhibitor. Characterization of the human elastase inhibitor molecule associated with monocytes, macrophages, and neutrophils

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Mutation of antitrypsin to antithrombin. alpha 1-antitrypsin Pittsburgh (358 Met leads to Arg), a fatal bleeding disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Structure of a serpin-protease complex shows inhibition by deformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Control of the coagulation system by serpins. Getting by with a little help from glycosaminoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Human plasma proteinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Phylogeny of the serpin superfamily: implications of patterns of amino acid conservation for structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The serpins are an expanding superfamily of structurally similar but functionally diverse proteins. Evolution, mechanism of inhibition, novel functions, and a revised nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

A genomic view of the complexity of mammalian proteolytic systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Alpha-1-antitrypsin deficiency: current concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Alpha1-antitrypsin deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Inhibition of lipopolysaccharide-mediated human monocyte activation, in vitro, by alpha1-antitrypsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Alpha1-antitrypsin inhibits Moraxella catarrhalis MID protein-induced tonsillar B cell proliferation and IL-6 release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Human alpha-1-antichymotrypsin: interaction with chymotrypsin-like proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

SERPINA3 (aka alpha-1-antichymotrypsin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Identification of centerin: a novel human germinal center B cell-restricted serpin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Molecular characterization of centerin, a germinal centre cell serpin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

C1 inhibitor: molecular and clinical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

C1 inhibitor prevents Gram-negative bacterial lipopolysaccharide-induced vascular permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

A direct role for C1 inhibitor in regulation of leukocyte adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The undecided serpin. The ins and outs of plasminogen activator inhibitor type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Inhibition of retinoblastoma protein degradation by interaction with the serpin plasminogen activator inhibitor 2 via a novel consensus motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Plasminogen activator inhibitor type 2: a regulator of monocyte proliferation and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Molecular Cloning of Bomapin (Protease Inhibitor 10), a Novel Human Serpin That Is Expressed Specifically in the Bone Marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Neutrophil elastase: path clearer, pathogen killer, or just pathologic?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Neutrophil elastase: mediator of extracellular matrix destruction and accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Nucleocytoplasmic distribution of the ovalbumin serpin PI-9 requires a nonconventional nuclear import pathway and the export factor Crm1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Gene structure, chromosomal localization, and expression of the murine homologue of human proteinase inhibitor 6 (PI-6) suggests divergence of PI-6 from the ovalbumin serpins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Cloning and molecular characterization of a human intracellular serine proteinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

SerpinB6 is an inhibitor of kallikrein-8 in keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Intracellular serpin SERPINB6 (PI6) is abundantly expressed by human mast cells and forms complexes with beta-tryptase monomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Selective regulation of apoptosis: the cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

A new family of 10 murine ovalbumin serpins includes two homologs of proteinase inhibitor 8 and two homologs of the granzyme B inhibitor (proteinase inhibitor 9).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Granzymes: exogenous proteinases that induce target cell apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Granzyme B: pro-apoptotic, antiviral and antitumor functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The major human and mouse granzymes are structurally and functionally divergent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Modulation of the granzyme B inhibitor proteinase inhibitor 9 (PI-9) by activation of lymphocytes and monocytes in vitro and by Epstein-Barr virus and bacterial infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Human and murine granzyme B exhibit divergent substrate preferences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The granzyme B inhibitor, protease inhibitor 9, is mainly expressed by dendritic cells and at immune-privileged sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Caspase-1 (interleukin-1β-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Serine protease inhibitor 6 protects cytotoxic T cells from self-inflicted injury by ensuring the integrity of cytotoxic granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Differential survival of cytotoxic T cells and memory cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

A role for the granzyme B inhibitor serine protease inhibitor 6 in CD8+ memory cell homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Proteinase inhibitor-9 expression is induced by maturation in dendritic cells via p38 MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The granzyme B inhibitor proteinase inhibitor 9 (PI9) is expressed by human mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Macrophages express granzyme B in the lesion areas of atherosclerosis and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The transcriptome of human cytotoxic T cells: similarities and disparities among allostimulated CD4(+) CTL, CD8(+) CTL and NK cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The restricted expression of granzyme M in human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Human neutrophils lack granzyme A, granzyme B, and perforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Granzyme B and perforin: constitutive expression in human polymorphonuclear neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Serine protease inhibitor 6-deficient mice have increased neutrophil immunity to Pseudomonas aeruginosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The granzyme B inhibitor SERPINB9 (protease inhibitor 9) circulates in blood and increases on primary cytomegalovirus infection after renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Intrahepatic lymphocyte expression of dipeptidyl peptidase I-processed granzyme B and perforin induces hepatocyte expression of serine proteinase inhibitor 6 (Serpinb9/SPI-6).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Antiviral cytokines induce hepatic expression of the granzyme B inhibitors, proteinase inhibitor 9 and serine proteinase inhibitor 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

The role of serpinb9/serine protease inhibitor 6 in preventing granzyme B-dependent hepatotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Serpin-6 expression protects embryonic stem cells from lysis by antigen-specific CTL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Identification of genes with abnormal expression changes in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Expression of the granzyme B inhibitor, protease inhibitor 9, by tumor cells in patients with non-Hodgkin and Hodgkin lymphoma: a novel protective mechanism for tumor cells to circumvent the immune system?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

Expression of the granzyme B inhibitor PI9 predicts outcome in nasal NK/T-cell lymphoma: results of a Western series of 48 patients treated with first-line polychemotherapy within the Groupe d'Etude des Lymphomes de l'Adulte (GELA) trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1399-0039.2008.01059.X

10.1111/J.1399-0039.2008.01059.X

21 January 2018

Identifiers

DOI

1 reference

18 August 2017

1 reference