(Q37171819)

18 August 2017

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title

Changing directions in the study of chemotaxis (English)

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18 August 2017

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Robert R Kay

1

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18 August 2017

Paul Langridge

series ordinal

2

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18 August 2017

David Traynor

series ordinal

3

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18 August 2017

Oliver Hoeller

series ordinal

4

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18 August 2017

publication date

1 June 2008

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Nature Reviews Molecular Cell Biology

18 August 2017

published in

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18 August 2017

volume

9

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18 August 2017

issue

6

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18 August 2017

page(s)

455-463

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The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells.

18 August 2017

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G protein signaling events are activated at the leading edge of chemotactic cells

31 March 2020

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Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

31 March 2020

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Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton

31 March 2020

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Polarization of chemoattractant receptor signaling during neutrophil chemotaxis

31 March 2020

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31 March 2020

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Quantitative elucidation of a distinct spatial gradient-sensing mechanism in fibroblasts

31 March 2020

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Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

31 March 2020

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31 March 2020

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G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility

31 March 2020

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31 March 2020

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Locally controlled inhibitory mechanisms are involved in eukaryotic GPCR-mediated chemosensing

31 March 2020

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Leukocytes navigate by compass: roles of PI3Kgamma and its lipid products

31 March 2020

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Two phases of actin polymerization display different dependencies on PI(3,4,5)P3 accumulation and have unique roles during chemotaxis

31 March 2020

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Do phosphoinositide 3-kinases direct lymphocyte navigation?

31 March 2020

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Role of phosphatidylinositol 3' kinase and a downstream pleckstrin homology domain-containing protein in controlling chemotaxis in dictyostelium

31 March 2020

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Distinct roles of PI(3,4,5)P3 during chemoattractant signaling in Dictyostelium: a quantitative in vivo analysis by inhibition of PI3-kinase

31 March 2020

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Role of phosphatidylinositol 3-kinases in chemotaxis in Dictyostelium

31 March 2020

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Chemotaxis in the Absence of PIP3 Gradients

31 March 2020

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The phosphatidylinositol 3-kinase inhibitor wortmannin markedly reduces chemotactic peptide-induced locomotion and increases in cytoskeletal actin in human neutrophils

31 March 2020

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Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases

31 March 2020

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Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement

31 March 2020

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PI(3)Kγ has an important context-dependent role in neutrophil chemokinesis

31 March 2020

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PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP.

31 March 2020

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Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

31 March 2020

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Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration

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Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction

31 March 2020

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Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

31 March 2020

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An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients

31 March 2020

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Chemoattractant-induced Ras activation during Dictyostelium aggregation

31 March 2020

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Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

31 March 2020

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Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum

31 March 2020

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Rap1 activation in response to cAMP occurs downstream of ras activation during Dictyostelium aggregation.

31 March 2020

1 reference

A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium

31 March 2020

1 reference

TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium

31 March 2020

1 reference

PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis

31 March 2020

1 reference

Essential role of PI3-kinase and phospholipase A2 in Dictyostelium discoideum chemotaxis

31 March 2020

1 reference

Four key signaling pathways mediating chemotaxis in Dictyostelium discoideum

31 March 2020

1 reference

Ca(2+) signalling is not required for chemotaxis in Dictyostelium

31 March 2020

1 reference

A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium

31 March 2020

1 reference

Three-dimensional dynamics of pseudopod formation and the regulation of turning during the motility cycle of Dictyostelium

31 March 2020

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Cellular motility driven by assembly and disassembly of actin filaments

31 March 2020

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Crawling toward a unified model of cell mobility: spatial and temporal regulation of actin dynamics.

31 March 2020

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Endocytosis: relation to capping and cell locomotion

31 March 2020

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The direction of membrane lipid flow in locomoting polymorphonuclear leukocytes

31 March 2020

1 reference

Possible roles of the endocytic cycle in cell motility

31 March 2020

1 reference

Actin microfilament dynamics in locomoting cells

31 March 2020

1 reference

Single-molecule speckle analysis of actin filament turnover in lamellipodia

31 March 2020

1 reference

Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia

31 March 2020

1 reference

Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells

31 March 2020

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Differentially oriented populations of actin filaments generated in lamellipodia collaborate in pushing and pausing at the cell front

31 March 2020

1 reference

Mechanism of actin-based motility.

31 March 2020

1 reference

Cell motility driven by actin polymerization

31 March 2020

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The ARP2/3 complex: an actin nucleator comes of age

31 March 2020

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The WASP-Arp2/3 pathway: genetic insights

31 March 2020

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Molecular requirements for actin-based lamella formation in Drosophila S2 cells

31 March 2020

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Mutants in the Dictyostelium Arp2/3 complex and chemoattractant-induced actin polymerization

31 March 2020

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Protein complexes regulating Arp2/3-mediated actin assembly.

31 March 2020

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Nap1 regulates Dictyostelium cell motility and adhesion through SCAR-dependent and -independent pathways.

31 March 2020

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A Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxis

31 March 2020

1 reference

The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia.

31 March 2020

1 reference

Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension

31 March 2020

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Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks

31 March 2020

1 reference

Eukaryotic cell locomotion depends on the propagation of self-organized reaction-diffusion waves and oscillations of actin filament assembly

31 March 2020

1 reference

Dynamic Actin Patterns and Arp2/3 Assembly at the Substrate-Attached Surface of Motile Cells

31 March 2020

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Subsecond reorganization of the actin network in cell motility and chemotaxis

31 March 2020

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Mobile actin clusters and traveling waves in cells recovering from actin depolymerization

31 March 2020

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An actin-based wave generator organizes cell motility

31 March 2020

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Actin polymerization and intracellular solvent flow in cell surface blebbing

31 March 2020

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Protrusive activity, cytoplasmic compartmentalization, and restriction rings in locomoting blebbing Walker carcinosarcoma cells are related to detachment of cortical actin from the plasma membrane

31 March 2020

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Non-equilibration of hydrostatic pressure in blebbing cells.

31 March 2020

1 reference

Dissection of amoeboid movement into two mechanically distinct modes.

31 March 2020

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Blebbing of Dictyostelium cells in response to chemoattractant

31 March 2020

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Reassembly of contractile actin cortex in cell blebs

31 March 2020

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Surface activity and locomotion of Fundulus deep cells during blastula and gastrula stages

31 March 2020

1 reference

Migration of zebrafish primordial germ cells: a role for myosin contraction and cytoplasmic flow.

31 March 2020

1 reference

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

31 March 2020

1 reference

How well can an amoeba climb?

31 March 2020

1 reference

Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain

31 March 2020

1 reference

Cross-linking of actin filaments by myosin II is a major contributor to cortical integrity and cell motility in restrictive environments

31 March 2020

1 reference

Differences in cortical actin structure and dynamics document that different types of blebs are formed by distinct mechanisms

31 March 2020

1 reference

Ca2+- and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils

31 March 2020

1 reference

Three-dimensional motility cycle in leukocytes

31 March 2020

1 reference

Dictyostelium cell shape generation requires myosin II

31 March 2020

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Mechanical properties of the red cell membrane in relation to molecular structure and genetic defects

31 March 2020

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Circulation of the plasma membrane in Dictyostelium

31 March 2020

1 reference

Mechano-chemical signaling maintains the rapid movement of Dictyostelium cells

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRM2419

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18 August 2017

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