(Q37176104)

18 August 2017

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title

NOX enzymes as novel targets for drug development (English)

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18 August 2017

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J David Lambeth

1

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18 August 2017

Karl-Heinz Krause

series ordinal

2

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18 August 2017

Robert A Clark

series ordinal

3

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18 August 2017

publication date

29 May 2008

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Seminars in Immunopathology

18 August 2017

published in

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18 August 2017

volume

30

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18 August 2017

issue

3

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18 August 2017

page(s)

339-363

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Inhibition of NAD(P)H oxidase activity blocks vascular endothelial growth factor overexpression and neovascularization during ischemic retinopathy.

18 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

The relationship of diphenyleneiodonium-induced hypoglycaemia to the specific covalent modification of NADH-ubiquinone oxidoreductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Free radicals in the physiological control of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Mechanisms for suppressing NADPH oxidase in the vascular wall

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Increased oxidative stress in obesity and its impact on metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

NAD(P)H oxidase 1, a product of differentiated colon epithelial cells, can partially replace glycoprotein 91phox in the regulated production of superoxide by phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Reversal of systemic hypertension-associated cardiac remodeling in chronic pressure overload myocardium by ciglitazone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Regulation of postischemic liver injury following different durations of ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Endothelial cell oxidant production: effect of NADPH oxidase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Current concepts: immunology. Neutrophils in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Identification of a superoxide-generating NADPH oxidase system in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Bicarbonate-dependent superoxide release and pulmonary artery tone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

In the absence of reactive oxygen species, T cells default to a Th1 phenotype and mediate protection against pulmonary Cryptococcus neoformans infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Effect of the NADPH oxidase inhibitor apocynin on septic lung injury in guinea pigs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Tissue destruction by neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0123-6

Diffusion of peroxynitrite in the presence of carbon dioxide

21 January 2018

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12 December 2020

Nox regulation of smooth muscle contraction

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12 December 2020

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction

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12 December 2020

Regulation of proliferation of skeletal muscle precursor cells by NADPH oxidase

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12 December 2020

Superoxide activates mitochondrial uncoupling proteins

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12 December 2020

Apocynin protects against global cerebral ischemia-reperfusion-induced oxidative stress and injury in the gerbil hippocampus

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12 December 2020

Guinea pig gastric mucosal cells produce abundant superoxide anion through an NADPH oxidase-like system

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12 December 2020

Activation of AP-1 and Nuclear Factor-κB Transcription Factors Is Involved in Hydrogen Peroxide-Induced Apoptotic Cell Death of Olligodendrocytes

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12 December 2020

Role of reactive oxygen species in the pathophysiology of human reproduction.

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12 December 2020

VEGF signaling through NADPH oxidase-derived ROS.

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12 December 2020

Nuclear factor-kappaB activation by reactive oxygen species mediates voltage-gated K+ current enhancement by neurotoxic beta-amyloid peptides in nerve growth factor-differentiated PC-12 cells and hippocampal neurones

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12 December 2020

Reactive oxygen species and signal transduction

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12 December 2020

Mitochondria, oxygen free radicals, and apoptosis

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12 December 2020

Mitochondrial diseases in man and mouse

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12 December 2020

Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatment

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12 December 2020

Oxidative protein cross-linking reactions involving L-tyrosine in transforming growth factor-beta1-stimulated fibroblasts

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12 December 2020

Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in experimentally induced asthma

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12 December 2020

Reactive oxygen species (ROS) generated by xanthine oxidase in the corneal epithelium and their potential participation in the damage of the corneal epithelium after prolonged use of contact lenses in rabbits

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12 December 2020

TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells

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12 December 2020

Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells.

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12 December 2020

Interaction of reactive oxygen species with ion transport mechanisms.

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12 December 2020

Nitric oxide and oxygen radicals in infection, inflammation, and cancer.

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12 December 2020

Mapping sites of interaction of p47-phox and flavocytochrome b with random-sequence peptide phage display libraries

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12 December 2020

On the mechanism of inhibition of the neutrophil respiratory burst oxidase by a peptide from the C-terminus of the large subunit of cytochrome b558

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12 December 2020

The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction

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12 December 2020

Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells

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12 December 2020

Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice.

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12 December 2020

Novel NAD(P)H oxidase inhibitor suppresses angioplasty-induced superoxide and neointimal hyperplasia of rat carotid artery

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12 December 2020

Stimulatory autoantibodies to the PDGF receptor: a link to fibrosis in scleroderma and a pathway for novel therapeutic targets.

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12 December 2020

NADPH oxidase inhibitors: new antihypertensive agents?

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12 December 2020

Nox2-containing NADPH oxidase and Akt activation play a key role in angiotensin II-induced cardiomyocyte hypertrophy.

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12 December 2020

Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein

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12 December 2020

Chronic inflammation and cancer

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12 December 2020

Ionizing radiation-induced micronucleus formation is mediated by reactive oxygen species that are produced in a manner dependent on mitochondria, Nox1, and JNK

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12 December 2020

Microparticle subpopulations are increased in preeclampsia: Possible involvement in vascular dysfunction?

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12 December 2020

A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats

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12 December 2020

Relationship between Superoxide Anion Radical and Anion Transport Protein of Red Blood Cell Membrane

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12 December 2020

Role of AT1 receptors and NAD(P)H oxidase in diabetes-aggravated ischemic brain injury

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12 December 2020

A constitutive NADPH oxidase-like system containing gp91phox homologs in human keratinocytes.

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12 December 2020

Neutrophil granule contents in the pathogenesis of lung injury

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12 December 2020

Activation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damage

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12 December 2020

Activation of NADPH oxidase during progression of cardiac hypertrophy to failure

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12 December 2020

Inflammation: the role of peroxidase-derived products

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12 December 2020

Role of reactive metabolites of oxygen and nitrogen in partial liver transplantation: lessons learned from reduced-size liver ischaemia and reperfusion injury

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12 December 2020

Reactive oxygen species and molecular biology of ischemia/reperfusion.

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12 December 2020

Identification of renox, an NAD(P)H oxidase in kidney

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12 December 2020

Transforming growth factor-beta1 induces Nox4 NAD(P)H oxidase and reactive oxygen species-dependent proliferation in human pulmonary artery smooth muscle cells

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12 December 2020

Enzymic mechanisms of superoxide production

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12 December 2020

Increased superoxide production in nitrate tolerance is associated with NAD(P)H oxidase and aldehyde dehydrogenase 2 downregulation

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12 December 2020

A myocardial Nox2 containing NAD(P)H oxidase contributes to oxidative stress in human atrial fibrillation

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12 December 2020

Requirement of Rac1 in the development of cardiac hypertrophy.

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12 December 2020

NADH/NADPH oxidase and enhanced superoxide production in the mineralocorticoid hypertensive rat.

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12 December 2020

Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo

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12 December 2020

Regulation of Nox and Duox enzymatic activity and expression

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12 December 2020

Ischemia-reperfusion and cardioprotection: a delicate balance between reactive oxygen species generation and redox homeostasis

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12 December 2020

Nox1 regulates apoptosis and potentially stimulates branching morphogenesis in sinusoidal endothelial cells

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12 December 2020

Nox1 downstream of 12-lipoxygenase controls cell proliferation but not cell spreading of colon cancer cells

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12 December 2020

Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase

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12 December 2020

Redox signaling in angiogenesis: role of NADPH oxidase

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12 December 2020

Mapping of functional domains in p47(phox) involved in the activation of NADPH oxidase by "peptide walking".

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12 December 2020

Nicotinamide adenine dinucleotide phosphate oxidase in the formation of superoxide in osteoclasts

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12 December 2020

Effects of NADPH oxidase inhibitor in diabetic nephropathy

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12 December 2020

Increased myocardial NADPH oxidase activity in human heart failure

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12 December 2020

NADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis

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12 December 2020

Reversible inactivation of the tumor suppressor PTEN by H2O2

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12 December 2020

Diphenyleneiodonium sulfate, an NADPH oxidase inhibitor, prevents early alcohol-induced liver injury in the rat.

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12 December 2020

The neutrophil NADPH oxidase

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12 December 2020

Expression of mRNA for ROS-generating NADPH oxidases in the aging stomach

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12 December 2020

Novel redox-dependent regulation of NOX5 by the tyrosine kinase c-Abl

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12 December 2020

Endothelium-derived microparticles impair endothelial function in vitro

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12 December 2020

ECM remodeling in hypertensive heart disease

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12 December 2020

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

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12 December 2020

Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidant.

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12 December 2020

ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation

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12 December 2020

Overexpression of a novel superoxide-producing enzyme, NADPH oxidase 1, in adenoma and well differentiated adenocarcinoma of the human colon

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12 December 2020

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

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12 December 2020

Role of NADPH oxidase 4 in lipopolysaccharide-induced proinflammatory responses by human aortic endothelial cells

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12 December 2020

Stimulatory Autoantibodies to the PDGF Receptor in Systemic Sclerosis

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12 December 2020

Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response

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12 December 2020

Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice.

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12 December 2020

Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols

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12 December 2020

Role of NADPH oxidase-derived superoxide in reduced size liver ischemia and reperfusion injury

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12 December 2020

Regulation of growth and apoptosis of cultured guinea pig gastric mucosal cells by mitogenic oxidase 1

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12 December 2020

Evidence for cancer-associated expression of NADPH oxidase 1 (Nox1)-based oxidase system in the human stomach.

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12 December 2020

The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice

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12 December 2020

Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice

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12 December 2020

Reactive oxygen species and erectile dysfunction: possible role of NADPH oxidase.

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12 December 2020

Measurement and characterization of superoxide generation in microglial cells: evidence for an NADPH oxidase-dependent pathway

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12 December 2020

Roles of superoxide radical anion in signal transduction mediated by reversible regulation of protein-tyrosine phosphatase 1B

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12 December 2020

Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase

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12 December 2020

Nox 4 regulation of vascular smooth muscle cell differentiation marker gene expression

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12 December 2020

Mitochondria and apoptosis

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12 December 2020

NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

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12 December 2020

NADPH oxidase-derived superoxide anion mediates angiotensin II-induced cardiac hypertrophy

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12 December 2020

PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox

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12 December 2020

Role of oxidative stress in the pathogenesis of abdominal aortic aneurysms.

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12 December 2020

NADPH oxidases in cardiovascular health and disease

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12 December 2020

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease

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12 December 2020

TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death

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12 December 2020

Aging: a revisited theory based on free radicals generated by NOX family NADPH oxidases

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12 December 2020

Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+

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12 December 2020

Mineralocorticoid receptor blockade attenuates chronic overexpression of the renin-angiotensin-aldosterone system stimulation of reduced nicotinamide adenine dinucleotide phosphate oxidase and cardiac remodeling.

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12 December 2020

Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo

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12 December 2020

Role of NADPH oxidase in the vascular hypertrophic and oxidative stress response to angiotensin II in mice

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12 December 2020

Mapping of functional domains in the p22(phox) subunit of flavocytochrome b(559) participating in the assembly of the NADPH oxidase complex by "peptide walking"

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12 December 2020

Infectious disease, the innate immune response, and fibrosis

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12 December 2020

Oxygen free radical release in human failing myocardium is associated with increased activity of rac1-GTPase and represents a target for statin treatment

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12 December 2020

Oxidants painting the cysteine chapel: redox regulation of PTPs

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12 December 2020

Bone Morphogenic Protein-4 Induces Hypertension in Mice

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12 December 2020

Inhibiting pollen reduced nicotinamide adenine dinucleotide phosphate oxidase-induced signal by intrapulmonary administration of antioxidants blocks allergic airway inflammation

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12 December 2020

Kupffer cells generate superoxide anions and modulate reperfusion injury in rat livers after cold preservation

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12 December 2020

Hypoxia-dependent regulation of nonphagocytic NADPH oxidase subunit NOX4 in the pulmonary vasculature.

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12 December 2020

Increased expression of gp91phox homologues of NAD(P)H oxidase in the aortic media during chronic hypertension: involvement of the renin-angiotensin system.

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12 December 2020

Nox4 mediates TGF-beta1-induced retinoblastoma protein phosphorylation, proliferation, and hypertrophy in human airway smooth muscle cells.

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12 December 2020

Nitric oxide synthase activity in tissues of the bovine eye

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12 December 2020

Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice

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12 December 2020

Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

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12 December 2020

NADPH oxidase involvement in the pathology of Helicobacter pylori infection

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12 December 2020

Systemic sclerosis: a prototypic multisystem fibrotic disorder

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12 December 2020

Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes

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12 December 2020

Expression of isoforms of NADPH oxidase components in rat pancreatic islets

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12 December 2020

SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model

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12 December 2020

Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species

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12 December 2020

Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor

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12 December 2020

Novel Nox inhibitor of oxLDL-induced reactive oxygen species formation in human endothelial cells

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12 December 2020

Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy

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12 December 2020

Fundamental aspects of reactive oxygen species, or what's the matter with oxygen?

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12 December 2020

Myocardial ischaemia and reperfusion injury: reactive oxygen species and the role of neutrophil

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12 December 2020

A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes

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12 December 2020

NADPH oxidases in lung biology and pathology: host defense enzymes, and more

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12 December 2020

Inactivation of the small GTPase Rac1 protects the liver from ischemia/reperfusion injury in the rat

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12 December 2020

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

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12 December 2020

Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity

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12 December 2020

Expression of nonphagocytic NADPH oxidase system in the ocular lens.

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12 December 2020

Reactive oxygen species are generated through a BLT2-linked cascade in Ras-transformed cells

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12 December 2020

Release of reactive oxygen by hepatocytes on reoxygenation: three phases and role of mitochondria.

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12 December 2020

The role of the electron transport SDHC gene on lifespan and cancer

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12 December 2020

NOX in liver fibrosis

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12 December 2020

An absence of reactive oxygen species improves the resolution of lung influenza infection.

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12 December 2020

Prenyltransferase inhibitors block superoxide production by pulmonary vascular smooth muscle

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12 December 2020

Nox1 is over-expressed in human colon cancers and correlates with activating mutations in K-Ras.

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12 December 2020

Branched fungal beta-glucan causes hyperinflammation and necrosis in phagocyte NADPH oxidase-deficient mice

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12 December 2020

Oral administration of the NADPH-oxidase inhibitor apocynin partially restores diminished cartilage proteoglycan synthesis and reduces inflammation in mice

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12 December 2020

Mitochondria are a major source of paraquat-induced reactive oxygen species production in the brain

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12 December 2020

The biochemical basis of the NADPH oxidase of phagocytes.

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12 December 2020

A role for NOX NADPH oxidases in Alzheimer's disease and other types of dementia?

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12 December 2020

NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells

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12 December 2020

Inhibition of NADPH oxidase reduces myocardial oxidative stress and apoptosis and improves cardiac function in heart failure after myocardial infarction

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12 December 2020

The role of reactive oxygen species in the regulation of tubular function

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12 December 2020

Analysis of dihydroethidium fluorescence for the detection of intracellular and extracellular superoxide produced by NADPH oxidase

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12 December 2020

Overexpression of Akt converts radial growth melanoma to vertical growth melanoma.

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12 December 2020

Diphenyleneiodonium suppresses apoptosis in cerulein-stimulated pancreatic acinar cells

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12 December 2020

Angiotensin II-dependent chronic hypertension and cardiac hypertrophy are unaffected by gp91phox-containing NADPH oxidase.

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12 December 2020

Toll-like receptor 4 deficiency causes pulmonary emphysema.

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12 December 2020

Hepatic expression of candidate genes in patients with alcoholic hepatitis: correlation with disease severity.

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12 December 2020

Nox4 is critical for hypoxia-inducible factor 2-alpha transcriptional activity in von Hippel-Lindau-deficient renal cell carcinoma

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12 December 2020

The role of CXC chemokines in pulmonary fibrosis

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12 December 2020

Pressure overload-induced myocardial hypertrophy in mice does not require gp91phox

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12 December 2020

Elevated plasma endothelial microparticles: preeclampsia versus gestational hypertension

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12 December 2020

Are mitochondria a permanent source of reactive oxygen species?

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12 December 2020

Oxidative stress and male reproductive biology.

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12 December 2020

Targeted inhibition of the small GTPase protects against ischemia/reperfusion liver injury in mice

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12 December 2020

Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney

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12 December 2020

Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line

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12 December 2020

NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts

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12 December 2020

NADPH oxidases: new players in TNF-induced necrotic cell death

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12 December 2020

The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle

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12 December 2020

Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol

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12 December 2020

Nox1-based NADPH oxidase is the major source of UVA-induced reactive oxygen species in human keratinocytes

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12 December 2020

Redox regulation of signal transduction in cardiac and smooth muscle

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12 December 2020

NAD(P)H oxidase and multidrug resistance protein genetic polymorphisms are associated with doxorubicin-induced cardiotoxicity

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12 December 2020

Are mitochondria a spontaneous and permanent source of reactive oxygen species?

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12 December 2020

Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice

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12 December 2020

NADPH oxidase: recent evidence for its role in erectile dysfunction

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12 December 2020

A new arthritis therapy with oxidative burst inducers

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12 December 2020

Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure

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12 December 2020

Oxidative stress and altered endothelial cell function in preeclampsia

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12 December 2020

A domain of p47phox that interacts with human neutrophil flavocytochrome b558.

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12 December 2020

Decreased blood pressure in NOX1-deficient mice

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12 December 2020

New phenotypes in thyroid dyshormonogenesis: hypothyroidism due to DUOX2 mutations

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12 December 2020

Attenuation of NADPH oxidase activation and glomerular filtration barrier remodeling with statin treatment

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12 December 2020

Reactive oxygen species, but not Ca2+ overloading, trigger pH- and mitochondrial permeability transition-dependent death of adult rat myocytes after ischemia-reperfusion

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12 December 2020

Contrasting roles of NADPH oxidase isoforms in pressure-overload versus angiotensin II-induced cardiac hypertrophy

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12 December 2020

Free oxygen radicals regulate plasma membrane Ca2+- and K+-permeable channels in plant root cells

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12 December 2020

Mitogenic signaling via platelet-derived growth factor beta in metanephric mesenchymal cells

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12 December 2020

Ethanol augments PDGF-induced NADPH oxidase activity and proliferation in rat pancreatic stellate cells

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12 December 2020

Killing activity of neutrophils is mediated through activation of proteases by K+ flux

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12 December 2020

Functional domain in an arginine-rich carboxyl-terminal region of p47phox

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12 December 2020

Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins

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12 December 2020

NAD(P)H oxidases and TGF-beta-induced cardiac fibroblast differentiation: Nox-4 gets Smad

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12 December 2020

Dioxin increases reactive oxygen production in mouse liver mitochondria

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12 December 2020

Targeting reactive oxygen species in hypertension

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12 December 2020

Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid

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12 December 2020

Polyunsaturated fatty acids modulate NOX 4 anion superoxide production in human fibroblasts

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12 December 2020

cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells

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12 December 2020

The inhibitory effects of some iodonium compounds on the superoxide generating system of neutrophils and their failure to inhibit diaphorase activity.

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12 December 2020

Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia

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12 December 2020

The heme component of the neutrophil NADPH oxidase complex is a target for aryliodonium compounds

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12 December 2020

Superoxide anion radical (O2-.), superoxide dismutases, and related matters

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12 December 2020

Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

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12 December 2020

Involvement of Nox2 NADPH oxidase in adverse cardiac remodeling after myocardial infarction

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12 December 2020

Cortical inhibitory neurons and schizophrenia

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12 December 2020

Tumor necrosis factor-alpha increases airway smooth muscle oxidants production through a NADPH oxidase-like system to enhance myosin light chain phosphorylation and contractility

1 reference

12 December 2020

Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure

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12 December 2020

Redox regulation of cellular signalling

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12 December 2020

Fer-mediated cortactin phosphorylation is associated with efficient fibroblast migration and is dependent on reactive oxygen species generation during integrin-mediated cell adhesion

1 reference

12 December 2020

Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system

1 reference

12 December 2020

Elevated plasma endothelial microparticles in preeclampsia

1 reference

12 December 2020

UV radiation down-regulates Dsg-2 via Rac/NADPH oxidase-mediated generation of ROS in human lens epithelial cells

1 reference

12 December 2020

Reactive oxygen species produced by NAD(P)H oxidase inhibit apoptosis in pancreatic cancer cells

1 reference

12 December 2020

Diphenylene iodonium as an inhibitor of the NADPH oxidase complex of bovine neutrophils. Factors controlling the inhibitory potency of diphenylene iodonium in a cell-free system of oxidase activation

1 reference

12 December 2020

NOX enzymes and the biology of reactive oxygen

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12 December 2020

Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs 1

1 reference

12 December 2020

Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase

1 reference

12 December 2020

Perivascular gene transfer of NADPH oxidase inhibitor suppresses angioplasty-induced neointimal proliferation of rat carotid artery

1 reference

12 December 2020

Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds

1 reference

12 December 2020

Role of reactive oxygen species in mediating hepatic ischemia-reperfusion injury and its therapeutic applications in liver transplantation

1 reference

12 December 2020

Reactive oxygen generated by Nox1 triggers the angiogenic switch

1 reference

12 December 2020

Oxidative stress is an important component of airway inflammation in mice exposed to cigarette smoke or lipopolysaccharide

1 reference

12 December 2020

Oxygen regulation of gene expression: a study in opposites

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12 December 2020

NOX2 and NOX4 mediate proliferative response in endothelial cells.

1 reference

12 December 2020

H2O2 but not O2- elevated by oxidized LDL enhances human aortic smooth muscle cell proliferation.

1 reference

12 December 2020

Nox1 expression determines cellular reactive oxygen and modulates c-fos-induced growth factor, interleukin-8, and Cav-1.

1 reference

12 December 2020

Molecular composition and regulation of the Nox family NAD(P)H oxidases

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12 December 2020

Pancreatic beta-cells express phagocyte-like NAD(P)H oxidase

1 reference

12 December 2020

Reactive oxygen species involved in prenylflavonoids, icariin and icaritin, initiating cardiac differentiation of mouse embryonic stem cells

1 reference

12 December 2020

S17834, a new inhibitor of cell adhesion and atherosclerosis that targets nadph oxidase

1 reference

12 December 2020

NAD(P)H oxidases regulate HIF-2alpha protein expression.

1 reference

12 December 2020

Three distinct mechanisms generate oxygen free radicals in neurons and contribute to cell death during anoxia and reoxygenation.

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12 December 2020

The NADPH oxidase NOX4 drives cardiac differentiation: Role in regulating cardiac transcription factors and MAP kinase activation

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12 December 2020

NOX5 variants are functionally active in endothelial cells

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12 December 2020

Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice.

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12 December 2020

Gp91phox-containing NAD(P)H oxidase increases superoxide formation by doxorubicin and NADPH.

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12 December 2020

Effect of NADPH oxidase inhibition on endothelial cell ELAM-1 mRNA expression

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12 December 2020

NOX1/NADPH oxidase negatively regulates nerve growth factor-induced neurite outgrowth.

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12 December 2020

Nox1 induces differentiation resistance in immortalized human keratinocytes generating cells that express simple epithelial keratins

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12 December 2020

Assembly of the phagocyte NADPH oxidase

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12 December 2020

Duox1 is the main source of hydrogen peroxide in the rat thyroid cell line PCCl3.

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12 December 2020

A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation

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12 December 2020

Regulation of the transcription factors NF-kappa B and AP-1 by redox changes

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12 December 2020

The phagocyte 47-kilodalton cytosolic oxidase protein is an early reactant in activation of the respiratory burst

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12 December 2020

Suppression of oxidative stress in the endothelium and vascular wall

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12 December 2020

Mitochondria and xanthine oxidase both generate reactive oxygen species in isolated perfused rat liver after hypoxic injury

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12 December 2020

Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2.

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12 December 2020

Nonphagocytic oxidase 1 causes death in lung epithelial cells via a TNF-RI-JNK signaling axis

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12 December 2020

Reactive oxygen species, mitochondria, apoptosis and aging.

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12 December 2020

Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor

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12 December 2020

IL-8 production and AP-1 transactivation induced by UVA in human keratinocytes: roles of D-alpha-tocopherol

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12 December 2020

Review article: the role of inflammation in the pathogenesis of gastric cancer

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12 December 2020

A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis.

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12 December 2020

Intracellular generation of reactive oxygen species by mitochondria

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12 December 2020

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

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12 December 2020

NOX3, a superoxide-generating NADPH oxidase of the inner ear

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12 December 2020

Measurement of in vivo oxidative stress regulated by the Rac1 GTPase.

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12 December 2020

Nox1-dependent superoxide production controls colon adenocarcinoma cell migration

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12 December 2020

The effect of natural antioxidants, NAO and apocynin, on oxidative stress in the rat heart following LPS challenge

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12 December 2020

Expression of Nox4 in osteoclasts

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12 December 2020

Role of xanthine oxidase and reactive oxygen intermediates in LPS- and TNF-induced pulmonary edema

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12 December 2020

Severe inflammation and reduced bacteria load in murine helicobacter infection caused by lack of phagocyte oxidase activity

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12 December 2020

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

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12 December 2020

Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts

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12 December 2020

A novel superoxide-producing NAD(P)H oxidase in kidney

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12 December 2020

Angiotensin II Type 1 Receptor Antagonism Mediates Uncoupling Protein 2-Driven Oxidative Stress and Ameliorates Pancreatic Islet β-Cell Function in Young Type 2 Diabetic Mice

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12 December 2020

NADPH oxidase NOX5-S mediates acid-induced cyclooxygenase-2 expression via activation of NF-kappaB in Barrett's esophageal adenocarcinoma cells

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12 December 2020

Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice

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12 December 2020

The oxidation of apocynin catalyzed by myeloperoxidase: proposal for NADPH oxidase inhibition

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12 December 2020

The oxidized deoxynucleoside triphosphate pool is a significant contributor to genetic instability in mismatch repair-deficient cells

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12 December 2020

Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis

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12 December 2020

Nox1 mediates basic fibroblast growth factor-induced migration of vascular smooth muscle cells.

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12 December 2020

Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, decreases cardiac oxidative stress and remodeling in Ren2 transgenic rats.

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12 December 2020

TGF-beta dependent regulation of oxygen radicals during transdifferentiation of activated hepatic stellate cells to myofibroblastoid cells

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12 December 2020

Regulation of macrophage activation in alcoholic liver disease

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12 December 2020

Pharmacological inhibition of neuronal NADPH oxidase protects against 1-methyl-4-phenylpyridinium (MPP+)-induced oxidative stress and apoptosis in mesencephalic dopaminergic neuronal cells

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12 December 2020

NADPH oxidase activity in preeclampsia with immortalized lymphoblasts used as models

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12 December 2020

A key role for the microglial NADPH oxidase in APP-dependent killing of neurons

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12 December 2020

The superoxide-generating NADPH oxidase: structural aspects and activation mechanism

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12 December 2020

Redox modifier genes in amyotrophic lateral sclerosis in mice.

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12 December 2020

The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation.

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12 December 2020

NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation.

1 reference

12 December 2020

Contribution of different Nox homologues to cardiac remodeling in two-kidney two-clip renovascular hypertensive rats: effect of valsartan

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12 December 2020

Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation.

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12 December 2020

10.1007/S00281-008-0123-6

Identifiers

DOI

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18 August 2017

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