(Q37183838)

18 August 2017

Dehydroalanine analog of glutathione: an electrophilic busulfan metabolite that binds to human glutathione S-transferase A1-1. (English)

1 reference

18 August 2017

1 reference

Islam R Younis

1

1 reference

18 August 2017

Meenal Elliott

2

1 reference

18 August 2017

Cody J Peer

3

1 reference

18 August 2017

Arthur J L Cooper

4

1 reference

18 August 2017

John T Pinto

5

1 reference

18 August 2017

Gregory W Konat

6

1 reference

18 August 2017

Michal Kraszpulski

7

1 reference

18 August 2017

William P Petros

8

1 reference

18 August 2017

Patrick S Callery

9

1 reference

18 August 2017

language of work or name

English

0 references

publication date

12 September 2008

1 reference

Journal of Pharmacology and Experimental Therapeutics

18 August 2017

1 reference

18 August 2017

327

1 reference

18 August 2017

3

1 reference

18 August 2017

770-776

1 reference

Metabolism of the cysteine S-conjugate of busulfan involves a beta-lyase reaction

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Dehydroalanine derived from cysteine is a common post-translational modification in human serum albumin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Quantitative analysis of polypeptide pharmaceuticals by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Lantibiotics: peptides of diverse structure and function.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

The biology of lantibiotics from the lacticin 481 group is coming of age.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Biosynthesis and mode of action of lantibiotics.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Optimizing treatment of chronic myeloid leukemia: a rational approach

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Hepatic veno-occlusive disease: pathogenesis, diagnosis and treatment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Beta-elimination: an unexpected artefact in proteome analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Loss of selenium from selenoproteins: conversion of selenocysteine to dehydroalanine in vitro

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Inactivation of creatine kinase by S-glutathionylation of the active-site cysteine residue

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Chemistry, biochemistry, nutrition, and microbiology of lysinoalanine, lanthionine, and histidinoalanine in food and other proteins

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Determination of tetrahydrothiophene formation as a probe of in vitro busulfan metabolism by human glutathione S-transferase A1-1: use of a highly sensitive gas chromatographic-mass spectrometric method

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Enzymes and transport systems involved in the formation and disposition of glutathione S-conjugates. Role in bioactivation and detoxication mechanisms of xenobiotics.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

The Role of Glutathione and Glutathione S-Transferases in Mercapturic Acid Biosynthesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Relative reactivities of sulfhydryl groups with N-acetyl dehydroalanine and N-acetyl dehydroalanine methyl ester

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Reactions of Proteins with Dehydroalanines

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Busulfan conjugation by glutathione S-transferases alpha, mu, and pi.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

The formation of dehydroalanine residues in alkali-treated insulin and oxidized glutathione. A nuclear-magnetic-resonance study

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

The preparation and subsequent identification of a dehydroalanyl peptide from alkali-treated oxidised glutathione

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Facile conversion of cysteine and alkyl cysteines to dehydroalanine on protein surfaces: versatile and switchable access to functionalized proteins.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Additivity rules using similarity models for chemical reactivity: calculation and interpretation of electrofugality and nucleofugality.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Glutathionylation of lens proteins through the formation of thioether bond

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Glutathione S-transferase M1 polymorphism: a risk factor for hepatic venoocclusive disease in bone marrow transplantation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Detoxication pathways involving glutathione and epoxide hydrolase in the in vitro metabolism of chloroprene

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Dehydroalanine-based inhibition of a peptide epimerase from spider venom

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2678891

Busulfan versus hydroxyurea in the treatment of polycythemia vera (PV) and essential thrombocythemia (ET)

3 September 2018

1 reference

12 December 2020

A biosynthetic route to dehydroalanine-containing proteins

1 reference

12 December 2020

Role of oxidative stress and glutathione in busulfan toxicity in cultured murine hepatocytes

1 reference

12 December 2020

Factors that affect the induction of gamma glutamyltransferase in epileptic patients receiving anti-convulsant drugs

1 reference

12 December 2020

Chronic myeloid leukemia

1 reference

12 December 2020

Biotransformation and quantitative determination of sulfur-containing metabolites of 1,4-dibromobutane in the rat

1 reference

12 December 2020

Polycythemia vera. A clinical study of 141 patients

1 reference

12 December 2020

Transition of myelofibrosis to polycythaemia vera

1 reference

12 December 2020

Cytotoxicity of treosulfan and busulfan on pediatric tumor cell lines

1 reference

12 December 2020

Biliary excretion of a glutathione conjugate of busulfan and 1,4-diiodobutane in the rat

1 reference

12 December 2020

Induction of glutathione synthesis explains pharmacodynamics of high-dose busulfan in mice and highlights putative mechanisms of drug interaction

1 reference

12 December 2020

Identifiers

DOI

10.1124/JPET.108.142208

1 reference

18 August 2017

1 reference

18 August 2017

PubMed publication ID

18791061

1 reference