(Q37189156)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

title

Elevated prothrombin promotes venous, but not arterial, thrombosis in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

0 references

6

1 reference

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2 March 2020

author name string

Maria M Aleman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Bethany L Walton

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

James R Byrnes

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Jian-Guo Wang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Matthew J Heisler

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Brian C Cooley

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Alisa S Wolberg

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

language of work or name

English

0 references

publication date

30 May 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

Arteriosclerosis, Thrombosis, and Vascular Biology

2 March 2020

published in

1 reference

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2 March 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

issue

8

1 reference

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2 March 2020

page(s)

1829-1836

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner

2 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Low-dose aspirin for preventing recurrent venous thromboembolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Murine models of thrombosis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Relationship between venous and arterial thrombosis: a review of the literature from a causal perspective.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Procoagulant activity induced by vascular injury determines contribution of elevated factor VIII to thrombosis and thrombus stability in mice.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

In vivo fluorescence imaging of large-vessel thrombosis in mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

An experimental model to study isolated effects of thrombin in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Erythrocyte hemolysis and hemoglobin oxidation promote ferric chloride-induced vascular injury

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Ultrastructure of activated mouse platelets: a qualitative scanning electron microscopy study.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Thrombin generation and fibrin clot structure

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Plasma fibrinogen gamma' chain content in the thrombotic microangiopathy syndrome.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

What does it take to make the perfect clot?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Association between factor V Leiden, prothrombin G20210A, and methylenetetrahydrofolate reductase C677T mutations and events of the arterial circulatory system: a meta-analysis of published studies

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

A targeted point mutation in thrombomodulin generates viable mice with a prethrombotic state

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

The prothrombin G20210A mutation and factor V Leiden mutation in patients with cerebrovascular disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

The heterozygous 20210 G/A prothrombin genotype is associated with early venous thrombosis in inherited thrombophilias and is not increased in frequency in artery disease

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Characterization of the cDNA coding for mouse prothrombin and localization of the gene on mouse chromosome 2.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Cross-modulatory effects of clopidogrel and heparin on platelet and fibrin incorporation in thrombosis

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

In vitro and in vivo evaluation of the effect of elevated factor VIII on the thrombogenic process.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Dysregulated coagulation associated with hypofibrinogenaemia and plasma hypercoagulability: implications for identifying coagulopathic mechanisms in humans.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Impact of procoagulant concentration on rate, peak and total thrombin generation in a model system

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

"Normal" thrombin generation.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Prothrombin G20210A mutant genotype is a risk factor for cerebrovascular ischemic disease in young patients.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

The transition G to A at position 20210 in the 3'-untranslated region of the prothrombin gene is not associated with cerebral ischemia.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779620

Elevated prothrombin results in clots with an altered fiber structure: a possible mechanism of the increased thrombotic risk

3 September 2018

1 reference

12 December 2020

Lack of association of the prothrombin gene variant G20210A with myocardial infarction in Caucasian males

1 reference

12 December 2020

Hyperprothrombinemia associated with prothrombin G20210A mutation inhibits plasma fibrinolysis through a TAFI-mediated mechanism

1 reference

12 December 2020

A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice

1 reference

12 December 2020

A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women

1 reference

12 December 2020

Increased prevalence of a polymorphism in the gene coding for human prothrombin in patients with coronary heart disease

1 reference

12 December 2020

Co-inheritance of the 20210A allele of the prothrombin gene increases the risk of thrombosis in subjects with familial thrombophilia

1 reference

12 December 2020

Prevalence of the prothrombin gene variant (nt20210A) in venous thrombosis and arterial disease

1 reference

12 December 2020

Interaction of coagulation defects and cardiovascular risk factors: increased risk of myocardial infarction associated with factor V Leiden or prothrombin 20210A

1 reference

12 December 2020

Geographic distribution of the 20210 G to A prothrombin variant

1 reference

12 December 2020

Clinical studies and thrombin generation in patients homozygous or heterozygous for the G20210A mutation in the prothrombin gene

1 reference

12 December 2020

Clinical and analytical relevance of the combination of prothrombin 20210A/A and factor V Leiden: results from a large family

1 reference

12 December 2020

Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall

1 reference

12 December 2020

Hyperprothrombinaemia-induced APC resistance: differential influence on fibrin formation and fibrinolysis

1 reference

12 December 2020

Differential effects of high prothrombin levels on thrombin generation depending on the cause of the hyperprothrombinemia

1 reference

12 December 2020

Mechanisms underlying FeCl3-induced arterial thrombosis

1 reference

12 December 2020

Venous and arterial thrombosis--pathogenesis and the rationale for anticoagulation

1 reference

12 December 2020

Towards a standardization of the murine ferric chloride-induced carotid arterial thrombosis model

1 reference

12 December 2020

Thrombin as a multi-functional enzyme

1 reference

12 December 2020

10.1161/ATVBAHA.113.301607

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23723374%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

23723374

1 reference