(Q37189412)

English

The interdependent, overlapping, and differential roles of type I and II IFNs in the pathogenesis of experimental autoimmune encephalomyelitis

scientific article published on 19 August 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

The interdependent, overlapping, and differential roles of type I and II IFNs in the pathogenesis of experimental autoimmune encephalomyelitis (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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experimental autoimmune encephalomyelitis

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author name string

Rodrigo Naves

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Simer P Singh

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Kevin S Cashman

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Amber L Rowse

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Robert C Axtell

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Lawrence Steinman

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

John D Mountz

7

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Chad Steele

8

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Patrizia De Sarno

9

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Chander Raman

10

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

language of work or name

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publication date

19 August 2013

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Journal of Immunology

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Europe PubMed Central

PMC publication ID

18 August 2017

191

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

2967-2977

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Lithium controls central nervous system autoimmunity through modulation of IFN-γ signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

CD5-dependent CK2 activation pathway regulates threshold for T cell anergy

1 reference

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6 September 2017

Discrepant effects of human interferon-gamma on clinical and immunological disease parameters in a novel marmoset model for multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Mechanisms of IFNγ regulation of autoimmune myocarditis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Type I IFN receptor regulates neutrophil functions and innate immunity to Leishmania parasites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Functional crosstalk between type I and II interferon through the regulated expression of STAT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Autoimmune T cell responses in the central nervous system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Regional CNS responses to IFN-gamma determine lesion localization patterns during EAE pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

A rush to judgment on Th17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Lithium prevents and ameliorates experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Central nervous system effects of current and emerging multiple sclerosis-directed immuno-therapies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Independent and Cooperative Antiviral Actions of Beta Interferon and Gamma Interferon against Herpes Simplex Virus Replication in Primary Human Fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Interferons at age 50: past, current and future impact on biomedicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Interferons in multiple sclerosis: ten years' experience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Interferon-beta: mechanism of action and dosing issues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Antigen presentation in the CNS by myeloid dendritic cells drives progression of relapsing experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Neurons produce type I interferon during viral encephalitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Type I interferons (alpha/beta) in immunity and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

T-cell properties determine disease site, clinical presentation, and cellular pathology of experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Molecular mechanisms regulating Th1 immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Multiple sclerosis and its treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Functional role of type I and type II interferons in antiviral defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Cytokines in neuroinflammatory disease: role of myelin autoreactive T cell production of interferon-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

6 September 2017

Leukemia inhibitory factor deficiency modulates the immune response and limits autoimmune demyelination: a new role for neurotrophic cytokines in neuroinflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

14 September 2017

Enhancing CTL responses to melanoma cell vaccines in vivo: synergistic increases obtained using IFNgamma primed and IFNbeta treated B7-1+ B16-F10 melanoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

14 September 2017

Cytokine localization in multiple sclerosis lesions: correlation with adhesion molecule expression and reactive nitrogen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

14 September 2017

The molecular cell biology of interferon-gamma and its receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

28 September 2017

Exacerbations of multiple sclerosis in patients treated with gamma interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

28 September 2017

Molecular mechanisms of high-dose antigen therapy in experimental autoimmune encephalomyelitis: rapid induction of Th1-type cytokines and inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

26 June 2018

Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

26 June 2018

Early treatment trials with interferon beta in multiple sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

26 June 2018

Monoclonal anti-gamma interferon antibodies enhance experimental allergic encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

26 June 2018

Immune modulation within the brain: recruitment of inflammatory cells and increased major histocompatibility antigen expression following intracerebral injection of interferon-gamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

26 June 2018

Effect of anti-interferon-gamma and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

26 June 2018

IFN-beta inhibits human Th17 cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

3 September 2018

The chemokine CCL5 is essential for leukocyte recruitment in a model of severe Herpes simplex encephalitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

3 September 2018

Microglia recognize double-stranded RNA via TLR3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

3 September 2018

IFN-gamma determines distinct clinical outcomes in autoimmune encephalomyelitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

3 September 2018

Cutting edge: critical role for CD5 in experimental autoimmune encephalomyelitis: inhibition of engagement reverses disease in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

3 September 2018

IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

3 September 2018

The role of IL-13 and its receptor in allergy and inflammatory responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

3 September 2018

Interferon-gamma confers resistance to experimental allergic encephalomyelitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

3 September 2018

Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

3 September 2018

Cytokine production by cells in cerebrospinal fluid during experimental allergic encephalomyelitis in SJL/J mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

3 September 2018

Interferon-gamma in progression to chronic demyelination and neurological deficit following acute EAE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

20 October 2018

Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

4 December 2018

LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3779698

4 December 2018

The inflamed central nervous system drives the activation and rapid proliferation of Foxp3+ regulatory T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergistic interactions between IFN-gamma and IFN-beta in priming murine macrophages for tumor cell killing

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in Lewis rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct injection of cytokines into the spinal cord causes autoimmune encephalomyelitis-like inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage-inactivating IL-13 suppresses experimental autoimmune encephalomyelitis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23960239

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1300419

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

0 references

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