(Q37200611)

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Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profiling

scientific article published on 03 March 2009

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scholarly article

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Europe PubMed Central

PMC publication ID

18 August 2017

Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profiling (English)

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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author name string

Liqun Yu

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Joana E Coelho

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Xiaoling Zhang

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Yutao Fu

4

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Abigail Tillman

5

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Ulas Karaoz

6

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Bertil B Fredholm

7

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Zhiping Weng

8

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Jiang-Fan Chen

9

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Europe PubMed Central

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18 August 2017

language of work or name

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publication date

3 March 2009

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Europe PubMed Central

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18 August 2017

Physiological Genomics

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Europe PubMed Central

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18 August 2017

37

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Europe PubMed Central

PMC publication ID

18 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

199-210

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Mice heterozygous for both A1 and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Caffeine analogs: biomedical impact

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Coffee and health: a review of recent human research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers

1 reference

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6 September 2017

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

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6 September 2017

Combination of adenosine A1 and A2A receptor blocking agents induces caffeine-like locomotor stimulation in mice

1 reference

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6 September 2017

Genetic and pharmacological inactivation of adenosine A2A receptor reveals an Egr-2-mediated transcriptional regulatory network in the mouse striatum

1 reference

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Coffee consumption and risk of type 2 diabetes: a systematic review

1 reference

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6 September 2017

Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine

1 reference

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6 September 2017

Binding of the prototypical adenosine A(2A) receptor agonist CGS 21680 to the cerebral cortex of adenosine A(1) and A(2A) receptor knockout mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

affy--analysis of Affymetrix GeneChip data at the probe level

1 reference

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Regulation of gene expression and cocaine reward by CREB and ΔFosB

1 reference

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6 September 2017

DNA microarrays: translation of the genome from laboratory to clinic

1 reference

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6 September 2017

Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Maternal consumption of coffee during pregnancy and stillbirth and infant death in first year of life: prospective study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Post-analysis follow-up and validation of microarray experiments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Prospective study of caffeine consumption and risk of Parkinson's disease in men and women.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.

1 reference

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6 September 2017

The role of the D(2) dopamine receptor (D(2)R) in A(2A) adenosine receptor (A(2A)R)-mediated behavioral and cellular responses as revealed by A(2A) and D(2) receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Association of coffee and caffeine intake with the risk of Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

The stimulant effects of caffeine on locomotor behaviour in mice are mediated through its blockade of adenosine A(2A) receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

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Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

1 reference

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6 September 2017

Actions of caffeine in the brain with special reference to factors that contribute to its widespread use.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Caffeine and theophylline analogues: correlation of behavioral effects with activity as adenosine receptor antagonists and as phosphodiesterase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

6 September 2017

Astra Award Lecture. Adenosine, adenosine receptors and the actions of caffeine

1 reference

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14 September 2017

Microarray analysis of gene expression during early adipocyte differentiation

1 reference

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Insulin and IGF-1 induce different patterns of gene expression in mouse fibroblast NIH-3T3 cells: identification by cDNA microarray analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

26 June 2018

Lack of tolerance to motor stimulant effects of a selective adenosine A(2A) receptor antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

26 June 2018

Purinergic inhibition of diazepam binding to rat brain ()

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

26 June 2018

Coffee, caffeine, and risk of type 2 diabetes: a prospective cohort study in younger and middle-aged U.S. women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

3 September 2018

Coffee and tea consumption are associated with a lower incidence of chronic liver disease in the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

3 September 2018

Coffee consumption, type 2 diabetes and impaired glucose tolerance in Swedish men and women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

3 September 2018

The adenosine A1 receptor contributes to the stimulatory, but not the inhibitory effect of caffeine on locomotion: a study in mice lacking adenosine A1 and/or A2A receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

3 September 2018

High caffeine consumption in the third trimester of pregnancy: gender-specific effects on fetal growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

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Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice.

1 reference

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Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive Impairment

1 reference

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3 September 2018

Association of maternal caffeine consumption with decrements in fetal growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

3 September 2018

Coffee consumption and risk of type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685498

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Caffeine intake and the risk of first-trimester spontaneous abortion

1 reference

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3 September 2018

The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions.

1 reference

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3 September 2018

Caffeine--an atypical drug of dependence.

1 reference

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3 September 2018

Fetal loss associated with caffeine intake before and during pregnancy.

1 reference

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Motor stimulant effects of the adenosine A2A receptor antagonist SCH 58261 do not develop tolerance after repeated treatments in 6-hydroxydopamine-lesioned rats

1 reference

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Moderate to heavy caffeine consumption during pregnancy and relationship to spontaneous abortion and abnormal fetal growth: a meta-analysis

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19258493

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19258493

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based on heuristic

inferred from PubMed ID database lookup

Rapid isolation of glomeruli coupled with gene expression profiling identifies downstream targets in Pod1 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19258493

12 December 2020

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inferred from PubMed ID database lookup

Biphasic changes in locomotor behavior and in expression of mRNA for NGFI-A and NGFI-B in rat striatum following acute caffeine administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/19258493

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inferred from PubMed ID database lookup

Dietary patterns and risk for type 2 diabetes mellitus in U.S. men

1 reference

https://pubmed.ncbi.nlm.nih.gov/19258493

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inferred from PubMed ID database lookup

Identifiers

10.1152/PHYSIOLGENOMICS.90353.2008

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

ResearchGate publication ID

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