(Q37200875)

English

Interrelationship between liver X receptor alpha, sterol regulatory element-binding protein-1c, peroxisome proliferator-activated receptor gamma, and small heterodimer partner in the transcriptional regulation of glucokinase gene expression in liver

scientific article published on 14 April 2009

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25 January 2020

Interrelationship between liver X receptor alpha, sterol regulatory element-binding protein-1c, peroxisome proliferator-activated receptor gamma, and small heterodimer partner in the transcriptional regulation of glucokinase gene expression in liver (English)

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25 January 2020

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25 January 2020

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Tae-Hyun Kim

1

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25 January 2020

Hail Kim

2

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25 January 2020

Joo-Man Park

3

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25 January 2020

Seung-Soon Im

4

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25 January 2020

Jin-Sik Bae

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25 January 2020

Mi-Young Kim

6

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25 January 2020

Ji-Young Cha

8

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25 January 2020

Kyung-Sup Kim

9

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14 April 2009

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25 January 2020

Journal of Biological Chemistry

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25 January 2020

284

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25 January 2020

15071-15083

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25 January 2020

Glucotoxicity in the INS-1 rat insulinoma cell line is mediated by the orphan nuclear receptor small heterodimer partner

1 reference

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Retinoid x receptor heterodimers in the metabolic syndrome

1 reference

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6 September 2017

Identification and characterization of peroxisome proliferator response element in the mouse GLUT2 promoter

1 reference

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6 September 2017

Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c

1 reference

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6 September 2017

Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver.

1 reference

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6 September 2017

Gene silencing by nuclear orphan receptors

1 reference

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6 September 2017

Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression

1 reference

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6 September 2017

Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD

1 reference

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6 September 2017

Occupancy and function of the -150 sterol regulatory element and -65 E-box in nutritional regulation of the fatty acid synthase gene in living animals

1 reference

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6 September 2017

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

1 reference

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6 September 2017

Liver X Receptor Signaling Pathways in Cardiovascular Disease

1 reference

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6 September 2017

The liver X receptor gene team: potential new players in atherosclerosis

1 reference

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6 September 2017

The small heterodimer partner interacts with the liver X receptor alpha and represses its transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Role of LXRs in control of lipogenesis

1 reference

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6 September 2017

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

1 reference

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6 September 2017

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Regulation of glucose production by the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Structure and expression of the orphan nuclear receptor SHP gene

1 reference

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6 September 2017

ADD1/SREBP1 activates PPARgamma through the production of endogenous ligand

1 reference

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6 September 2017

An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors

1 reference

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6 September 2017

The nuclear receptor superfamily: the second decade

1 reference

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6 September 2017

LXR, a nuclear receptor that defines a distinct retinoid response pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Differential expression and regulation of the glucokinase gene in liver and islets of Langerhans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Rat glucokinase gene: structure and regulation by insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Transcriptional induction of glucokinase gene by insulin in cultured liver cells and its repression by the glucagon-cAMP system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Glucokinase gene structure. Functional implications of molecular genetic studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

6 September 2017

Bile acids regulate gluconeogenic gene expression via small heterodimer partner-mediated repression of hepatocyte nuclear factor 4 and Foxo1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

14 September 2017

Liver glucokinase can be activated by peroxisome proliferator-activated receptor-gamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

14 September 2017

Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

14 September 2017

Peroxisomal proliferator-activated receptor-gamma upregulates glucokinase gene expression in beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

28 September 2017

The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

28 September 2017

Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

28 September 2017

Expression of the insulin-responsive glucose transporter GLUT4 in adipocytes is dependent on liver X receptor alpha

1 reference

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26 June 2018

Expression of human hepatic glucokinase in transgenic mice liver results in decreased glucose levels and reduced body weight.

1 reference

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26 June 2018

Lxralpha deficiency hampers the hepatic adaptive response to fasting in mice

1 reference

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3 September 2018

LXRs regulate the balance between fat storage and oxidation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

3 September 2018

SREBP-1c mediates the insulin-dependent hepatic glucokinase expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

3 September 2018

Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

3 September 2018

Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

3 September 2018

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

3 September 2018

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2685689

3 September 2018

Evidence from transgenic mice that glucokinase is rate limiting for glucose utilization in the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/19366697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Increased Glucokinase Gene Copy Number on Glucose Homeostasis and Hepatic Glucose Metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/19366697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation. Evidence against feedback inhibition of glucokinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19366697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation of SHP by PPAR-gamma in liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/19366697

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M109.006742

1 reference

Europe PubMed Central

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25 January 2020

1 reference

Europe PubMed Central

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25 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19366697%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

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