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The Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription.
scientific article published on 08 August 2013
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Europe PubMed Central
PMC publication ID
3787130
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
title
The Krüppel-like protein Gli-similar 3 (Glis3) functions as a key regulator of insulin transcription
(English)
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Europe PubMed Central
PMC publication ID
3787130
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
main subject
preproinsulin
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inferred from title
author
Anton M. Jetten
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3
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Europe PubMed Central
PMC publication ID
3787130
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
author name string
Gary T ZeRuth
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1
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Europe PubMed Central
PMC publication ID
3787130
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
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7 March 2020
Yukimasa Takeda
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2
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3787130
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
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7 March 2020
publication date
8 August 2013
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3787130
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retrieved
7 March 2020
published in
Molecular Endocrinology
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Europe PubMed Central
PMC publication ID
3787130
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
volume
27
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Europe PubMed Central
PMC publication ID
3787130
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
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7 March 2020
issue
10
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Europe PubMed Central
PMC publication ID
3787130
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7 March 2020
page(s)
1692-1705
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3787130
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
cites work
Systematic evaluation of validated type 2 diabetes and glycaemic trait loci for association with insulin clearance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Gli-similar proteins: their mechanisms of action, physiological functions, and roles in disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Variants in GLIS3 and CRY2 are associated with type 2 diabetes and impaired fasting glucose in Chinese Hans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Disruption of a novel Kruppel-like transcription factor p300-regulated pathway for insulin biosynthesis revealed by studies of the c.-331 INS mutation found in neonatal diabetes mellitus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Modulation of the transactivation function and stability of Krüppel-like zinc finger protein Gli-similar 3 (Glis3) by Suppressor of Fused.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
The Krüppel-like zinc finger protein Glis3 directly and indirectly activates insulin gene transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Glucose regulation of insulin gene expression in pancreatic beta-cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Functional analysis of the zinc finger and activation domains of Glis3 and mutant Glis3(NDH1)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Transcription factors regulating beta-cell function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
CBP and p300: HATs for different occasions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Pancreas duodenum homeobox-1 transcriptional activation requires interactions with p300
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
CREB-binding protein/p300 co-activation of crystallin gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Regulation of insulin gene transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
The H1 and H2 regions of the activation domain of herpes simplex virion protein 16 stimulate transcription through distinct molecular mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
p300/CBP proteins: HATs for transcriptional bridges and scaffolds
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Regulation of insulin gene transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
CBP/p300 in cell growth, transformation, and development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Transcription factor BETA2 acts cooperatively with E2A and PDX1 to activate the insulin gene promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
The homeodomain of PDX-1 mediates multiple protein-protein interactions in the formation of a transcriptional activation complex on the insulin promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Factor-specific modulation of CREB-binding protein acetyltransferase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
p300 mediates transcriptional stimulation by the basic helix-loop-helix activators of the insulin gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Transcriptional synergy between LIM-homeodomain proteins and basic helix-loop-helix proteins: the LIM2 domain determines specificity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Synergistic activation of the insulin gene by a LIM-homeo domain protein and a basic helix-loop-helix protein: building a functional insulin minienhancer complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
6 September 2017
Relative contribution of PDX-1, MafA and E47/beta2 to the regulation of the human insulin promoter
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
14 September 2017
A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
26 June 2018
Novel GLIS3 mutations demonstrate an extended multisystem phenotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
3 September 2018
A murine model of neonatal diabetes mellitus in Glis3-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
3 September 2018
Mutations in GLIS3 are responsible for a rare syndrome with neonatal diabetes mellitus and congenital hypothyroidism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3787130
retrieved
3 September 2018
A family of transcriptional adaptor proteins targeted by the E1A oncoprotein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23927931
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1210/ME.2013-1117
1 reference
stated in
Europe PubMed Central
PMC publication ID
3787130
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PMC publication ID
3787130
1 reference
stated in
Europe PubMed Central
PMC publication ID
3787130
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PubMed publication ID
23927931
1 reference
stated in
Europe PubMed Central
PMC publication ID
3787130
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23927931%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
ResearchGate publication ID
255714186
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