(Q37223043)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

corrigendum / erratum

Corrigendum: Ubiquitin ligase RNF20/40 facilitates spindle assembly and promotes breast carcinogenesis through stabilizing motor protein Eg5.

0 references

author

Kai Zhang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

author name string

Yang Duan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Dawei Huo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Jie Gao

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Heng Wu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Zheng Ye

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Zhe Liu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Lin Shan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Xing Zhou

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Yue Wang

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Dongxue Su

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Xiang Ding

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Lei Shi

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Yan Wang

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Yongfeng Shang

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Chenghao Xuan

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

language of work or name

English

0 references

publication date

25 August 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

volume

7

1 reference

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21 March 2020

page(s)

12648

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

The ubiquitin ligase MuRF1 regulates PPARα activity in the heart by enhancing nuclear export via monoubiquitination

21 March 2020

cites work

1 reference

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Rab1A is an mTORC1 activator and a colorectal oncogene

6 September 2017

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Aneuploidy in health, disease, and aging

6 September 2017

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Advances in the discovery of kinesin spindle protein (Eg5) inhibitors as antitumor agents.

6 September 2017

1 reference

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Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia

6 September 2017

1 reference

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Optimized S -Trityl- l -cysteine-Based Inhibitors of Kinesin Spindle Protein with Potent in Vivo Antitumor Activity in Lung Cancer Xenograft Models

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability

6 September 2017

1 reference

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Causes and consequences of aneuploidy in cancer.

6 September 2017

1 reference

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Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

GlcNAcylation of histone H2B facilitates its monoubiquitination

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

A potent chemotherapeutic strategy for bladder cancer: (S)-methoxy-trityl-L-cystein, a novel Eg5 inhibitor.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Mitotic functions of kinesin-5.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Linking cell cycle to histone modifications: SBF and H2B monoubiquitination machinery and cell-cycle regulation of H3K79 dimethylation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Exploring cellular memory molecules marking competent and active transcriptions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

To step or not to step? How biochemistry and mechanics influence processivity in Kinesin and Eg5.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Inhibitors of mitotic kinesins: next-generation antimitotics

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation

6 September 2017

1 reference

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Inhibitors of kinesin motor proteins--research and clinical progress

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Antitumor activity of a kinesin inhibitor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Protein regulation by monoubiquitin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

The spindle: a dynamic assembly of microtubules and motors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Rad6-dependent ubiquitination of histone H2B in yeast

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Regulation and targeting of Eg5, a mitotic motor protein in blast crisis CML: overcoming imatinib resistance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Sp1 and Sp3 foci distribution throughout mitosis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Expanding the role of HsEg5 within the mitotic and post-mitotic phases of the cell cycle.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

A synthetic lethal interaction between APC/C and topoisomerase poisons uncovered by proteomic screens.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

K858, a novel inhibitor of mitotic kinesin Eg5 and antitumor agent, induces cell death in cancer cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Mitotic partitioning of transcription factors.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5007379

Ectopic expression of the microtubule-dependent motor protein Eg5 promotes pancreatic tumourigenesis

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS12648

Overexpression of Eg5 causes genomic instability and tumor formation in mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27557628

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression of Eg5 predicts unfavorable prognosis in non-muscle invasive bladder urothelial carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27557628

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS12648

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27557628%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

27557628

1 reference