(Q37242616)

19 August 2017

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title

New insulin analogues and routes of delivery: pharmacodynamic and clinical considerations (English)

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19 August 2017

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Paris Roach

1

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19 August 2017

language of work or name

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1 January 2008

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Clinical Pharmacokinetics

19 August 2017

published in

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19 August 2017

volume

47

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19 August 2017

issue

9

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19 August 2017

page(s)

595-610

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Optimized Basal-bolus insulin regimens in type 1 diabetes: insulin glulisine versus regular human insulin in combination with Basal insulin glargine

19 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00003088-200847090-00003

Insulin across respiratory mucosae by aerosol delivery

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00003088-200847090-00003

Improved postprandial metabolic control after subcutaneous injection of a short-acting insulin analog in IDDM of short duration with residual pancreatic beta-cell function.

21 January 2018

1 reference

12 December 2020

Insulin aspart (B28 asp-insulin): a fast-acting analog of human insulin: absorption kinetics and action profile compared with regular human insulin in healthy nondiabetic subjects

1 reference

12 December 2020

Comparison of Pharmacokinetics and Dynamics of the Long-Acting Insulin Analogs Glargine and Detemir at Steady State in Type 1 Diabetes: A double-blind, randomized, crossover study

1 reference

12 December 2020

Time-action profile of the long-acting insulin analog insulin glargine (HOE901) in comparison with those of NPH insulin and placebo

1 reference

12 December 2020

1 reference

12 December 2020

Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetes

1 reference

12 December 2020

Future directions for insulin therapy and diabetes treatment

1 reference

12 December 2020

Engineering predictability and protraction in a basal insulin analogue: the pharmacology of insulin detemir

1 reference

12 December 2020

Injection-meal interval: recommendations of diabetologists and how patients handle it.

1 reference

12 December 2020

Postprandial insulin lispro. A new therapeutic option for type 1 diabetic patients

1 reference

12 December 2020

Factors influencing the absorption, serum insulin concentration, and blood glucose responses after injections of regular insulin and various insulin mixtures.

1 reference

12 December 2020

Efficacy and safety of inhaled insulin (exubera) compared with subcutaneous insulin therapy in patients with type 2 diabetes: results of a 6-month, randomized, comparative trial

1 reference

12 December 2020

Pharmacokinetic and glucodynamic variability: assessment of insulin glargine, NPH insulin and insulin ultralente in healthy volunteers using a euglycaemic clamp technique

1 reference

12 December 2020

Efficacy and safety of insulin glulisine in patients with type 1 diabetes

1 reference

12 December 2020

Optimal time of administration of insulin lispro. Importance of meal composition

1 reference

12 December 2020

Dose-response relationship of an oral insulin spray in six patients with type 1 diabetes: a single-center, randomized, single-blind, 5-way crossover study

1 reference

12 December 2020

Albumin-bound basal insulin analogues (insulin detemir and NN344): comparable time-action profiles but less variability than insulin glargine in type 2 diabetes

1 reference

12 December 2020

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

1 reference

12 December 2020

The lung as an alternative route of delivery for insulin in controlling postprandial glucose levels in patients with diabetes.

1 reference

12 December 2020

The impact of smoking on inhaled insulin.

1 reference

12 December 2020

A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir.

1 reference

12 December 2020

Intensive therapy with inhaled insulin via the AERx insulin diabetes management system: a 12-week proof-of-concept trial in patients with type 2 diabetes

1 reference

12 December 2020

Lower within-subject variability of fasting blood glucose and reduced weight gain with insulin detemir compared to NPH insulin in patients with type 2 diabetes

1 reference

12 December 2020

Novel methods of insulin delivery: an update

1 reference

12 December 2020

Comparison of three multiple injection regimens for Type 1 diabetes: morning plus dinner or bedtime administration of insulin detemir vs. morning plus bedtime NPH insulin

1 reference

12 December 2020

Long-term intensive treatment of type 1 diabetes with the short-acting insulin analog lispro in variable combination with NPH insulin at mealtime

1 reference

12 December 2020

The effect of the insulin analog lispro on nighttime blood glucose control in type 1 diabetic patients.

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro.

1 reference

12 December 2020

Oral spray insulin in treatment of type 2 diabetes: a comparison of efficacy of the oral spray insulin (Oralin) with subcutaneous (SC) insulin injection, a proof of concept study

1 reference

12 December 2020

Efficacy and safety of inhaled insulin (Exubera) compared with subcutaneous insulin therapy in patients with type 1 diabetes: results of a 6-month, randomized, comparative trial

1 reference

12 December 2020

Twice-daily compared with once-daily insulin glargine in people with Type 1 diabetes using meal-time insulin aspart

1 reference

12 December 2020

Alternative routes of insulin delivery

1 reference

12 December 2020

Insulin detemir and insulin aspart: a promising basal-bolus regimen for type 2 diabetes.

1 reference

12 December 2020

Clinical pharmacokinetics and pharmacodynamics of inhaled insulin

1 reference

12 December 2020

Insulin glulisine: a faster onset of action compared with insulin lispro.

1 reference

12 December 2020

[Lys(B28), Pro(B29)]-human insulin. A rapidly absorbed analogue of human insulin

1 reference

12 December 2020

Inhaled insulin using the AERx Insulin Diabetes Management System in healthy and asthmatic subjects

1 reference

12 December 2020

Concept, strategies, and feasibility of noninvasive insulin delivery

1 reference

12 December 2020

Monomeric insulins and their experimental and clinical implications

1 reference

12 December 2020

Technosphere/Insulin--a new approach for effective delivery of human insulin via the pulmonary route

1 reference

12 December 2020

No evidence for accumulation of insulin glargine (LANTUS): a multiple injection study in patients with Type 1 diabetes

1 reference

12 December 2020

Insulin glulisine provides improved glycemic control in patients with type 2 diabetes

1 reference

12 December 2020

Towards peakless, reproducible and long-acting insulins. An assessment of the basal analogues based on isoglycaemic clamp studies

1 reference

12 December 2020

Effect of insulin concentration, subcutaneous fat thickness and skin temperature on subcutaneous insulin absorption in healthy subjects

1 reference

12 December 2020

Improved glycaemic control with insulin glargine plus insulin lispro: a multicentre, randomized, cross-over trial in people with Type 1 diabetes

1 reference

12 December 2020

Oral delivery of insulin with the eligen technology: mechanistic studies

1 reference

12 December 2020

Optimal timing of injection of once-daily insulin glargine in people with Type 1 diabetes using insulin lispro at meal-times

1 reference

12 December 2020

Antibody response to inhaled insulin in patients with type 1 or type 2 diabetes. An analysis of initial phase II and III inhaled insulin (Exubera) trials and a two-year extension trial

1 reference

12 December 2020

A randomized clinical trial comparing breakfast, dinner, or bedtime administration of insulin glargine in patients with type 1 diabetes

1 reference

12 December 2020

Effects of QD insulin detemir or neutral protamine Hagedorn on blood glucose control in patients with type I diabetes mellitus using a basal-bolus regimen

1 reference

12 December 2020

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

1 reference

12 December 2020

To: Scholtz HE, Pretorius SG, Wessels DH, Becker RHA (2005) Pharmacokinetic and glucodynamic variability: assessment of insulin glargine, NPH insulin and insulin ultralente in healthy volunteers using a euglycaemic clamp technique. Diabetologia 48:1

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of the long-acting insulin analog glargine after 1 week of use compared with its first administration in subjects with type 1 diabetes

1 reference

12 December 2020

Dose-response relation of liquid aerosol inhaled insulin in type I diabetic patients

1 reference

12 December 2020

Time-action profile of the soluble, fatty acid acylated, long-acting insulin analogue NN304

1 reference

12 December 2020

1 reference

12 December 2020

Safety and efficacy of insulin detemir in clinical practice: 14-week follow-up data from type 1 and type 2 diabetes patients in the PREDICTIVE European cohort

1 reference

12 December 2020

Direct comparison of insulin lispro and aspart shows small differences in plasma insulin profiles after subcutaneous injection in type 1 diabetes

1 reference

12 December 2020

Large porous particles for pulmonary drug delivery

1 reference

12 December 2020

Parenteral absorption of insulin from the lung in diabetic children

1 reference

12 December 2020

Insulin detemir is associated with more predictable glycemic control and reduced risk of hypoglycemia than NPH insulin in patients with type 1 diabetes on a basal-bolus regimen with premeal insulin aspart

1 reference

12 December 2020

Oral modified insulin (HIM2) in patients with type 1 diabetes mellitus: results from a phase I/II clinical trial

1 reference

12 December 2020

Effects of the short-acting insulin analog [Lys(B28),Pro(B29)] on postprandial blood glucose control in IDDM

1 reference

12 December 2020

Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin) in basal-bolus therapy for patients with type 1 diabetes.

1 reference

12 December 2020

Efficacy of conversion from bedtime NPH insulin injection to once- or twice-daily injections of insulin glargine in type 1 diabetic patients using basal/bolus therapy

1 reference

12 December 2020

Time-action profile of inhaled insulin in comparison with subcutaneously injected insulin lispro and regular human insulin

1 reference

12 December 2020

Comparison of insulin detemir and insulin glargine in subjects with Type 1 diabetes using intensive insulin therapy

1 reference

12 December 2020

Long-term efficacy and safety of insulin detemir compared to Neutral Protamine Hagedorn insulin in patients with Type 1 diabetes using a treat-to-target basal-bolus regimen with insulin aspart at meals: a 2-year, randomized, controlled trial

1 reference

12 December 2020

Absorption of radiolabelled soluble insulin in type 1 (insulin-dependent) diabetes: influence of subcutaneous blood flow and anthropometry

1 reference

12 December 2020

Technosphere/Insulin--proof of concept study with a new insulin formulation for pulmonary delivery

1 reference

12 December 2020

Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects: a 6-month, randomized, comparative trial

1 reference

12 December 2020

Comparison of the pharmacokinetics and pharmacodynamics of biphasic insulin aspart and insulin glargine in people with type 2 diabetes

1 reference

12 December 2020

Meal composition is a determinant of lispro-induced hypoglycemia in IDDM

1 reference

12 December 2020

Insulin glulisine, a new rapid-acting insulin analogue, displays a rapid time-action profile in obese non-diabetic subjects

1 reference

12 December 2020

Novel forms of insulin delivery

1 reference

12 December 2020

Dose response of inhaled dry-powder insulin and dose equivalence to subcutaneous insulin lispro

1 reference

12 December 2020

Insulin detemir offers improved glycemic control compared with NPH insulin in people with type 1 diabetes: a randomized clinical trial

1 reference

12 December 2020

10.2165/00003088-200847090-00003

Identifiers

DOI

1 reference

Dimensions Publication ID

19 August 2017

1018667871

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