(Q37244992)

30 June 2019

review article

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title

The ghost in the machine: small GTPases as spatial regulators of exocytosis (English)

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30 June 2019

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Hao Wu

1

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30 June 2019

Guendalina Rossi

series ordinal

2

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30 June 2019

Patrick Brennwald

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3

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30 June 2019

language of work or name

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14 August 2008

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30 June 2019

published in

Trends in Cell Biology

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30 June 2019

volume

18

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30 June 2019

page(s)

397-404

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30 June 2019

issue

9

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30 June 2019

The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis

cites work

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12 December 2020

The small GTPase RalA targets filamin to induce filopodia

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12 December 2020

Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9

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12 December 2020

The Rho GTPase Rho3 has a direct role in exocytosis that is distinct from its role in actin polarity

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12 December 2020

RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endocytosis

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12 December 2020

Ordering the final events in yeast exocytosis

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12 December 2020

Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex

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12 December 2020

Spatial regulation of the exocyst complex by Rho1 GTPase

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12 December 2020

Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins.

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12 December 2020

Cdc42 interacts with the exocyst and regulates polarized secretion.

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12 December 2020

The Sec34/35 Golgi transport complex is related to the exocyst, defining a family of complexes involved in multiple steps of membrane traffic

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12 December 2020

Yeast Cdc42 functions at a late step in exocytosis, specifically during polarized growth of the emerging bud

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12 December 2020

The exocyst is a Ral effector complex

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12 December 2020

Rho1 directs formin-mediated actin ring assembly during budding yeast cytokinesis

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12 December 2020

Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p

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12 December 2020

The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin

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12 December 2020

Control of vesicular trafficking by Rho GTPases

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12 December 2020

Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEM1

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12 December 2020

Ral GTPases regulate exocyst assembly through dual subunit interactions

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12 December 2020

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

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12 December 2020

Three Yips for Rab recruitment

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12 December 2020

RalA but not RalB enhances polarized delivery of membrane proteins to the basolateral surface of epithelial cells

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12 December 2020

Sec15 is an effector for the Rab11 GTPase in mammalian cells

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12 December 2020

Vesicles carry most exocyst subunits to exocytic sites marked by the remaining two subunits, Sec3p and Exo70p

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12 December 2020

Hydrolysis of GTP by Sec4 protein plays an important role in vesicular transport and is stimulated by a GTPase-activating protein in Saccharomyces cerevisiae

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12 December 2020

Dimerization of the exocyst protein Sec6p and its interaction with the t-SNARE Sec9p.

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12 December 2020

Isolation and characterization of two novel ras superfamily genes in Saccharomyces cerevisiae

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12 December 2020

Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase

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12 December 2020

Ral GTPases: corrupting the exocyst in cancer cells

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12 December 2020

Structurally conserved interaction of Lgl family with SNAREs is critical to their cellular function

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12 December 2020

The Small GTPase RalA Controls Exocytosis of Large Dense Core Secretory Granules by Interacting with ARF6-dependent Phospholipase D1

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12 December 2020

Lethal giant larvae proteins interact with the exocyst complex and are involved in polarized exocytosis

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12 December 2020

Rho GTPase regulation of exocytosis in yeast is independent of GTP hydrolysis and polarization of the exocyst complex

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12 December 2020

Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo

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12 December 2020

Crystal structure of the S.cerevisiae exocyst component Exo70p

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12 December 2020

The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p

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12 December 2020

The exocyst defrocked, a framework of rods revealed.

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12 December 2020

Central roles of small GTPases in the development of cell polarity in yeast and beyond

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12 December 2020

Mechanism and function of formins in the control of actin assembly

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12 December 2020

Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism

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12 December 2020

Spatial regulation of exocytosis and cell polarity: yeast as a model for animal cells

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12 December 2020

Structure of the FH2 domain of Daam1: implications for formin regulation of actin assembly

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12 December 2020

Differential regulation and properties of MAPKs

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12 December 2020

Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation

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12 December 2020

Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane

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12 December 2020

Phosphatidylinositol 4,5-bisphosphate mediates the targeting of the exocyst to the plasma membrane for exocytosis in mammalian cells

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12 December 2020

Activation of RalA is required for insulin-stimulated Glut4 trafficking to the plasma membrane via the exocyst and the motor protein Myo1c

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12 December 2020

Membrane association and functional regulation of Sec3 by phospholipids and Cdc42

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12 December 2020

Structure and function of signal-transducing GTP-binding proteins

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12 December 2020

The Sec15 protein responds to the function of the GTP binding protein, Sec4, to control vesicular traffic in yeast

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12 December 2020

Do GTPases direct membrane traffic in secretion?

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12 December 2020

A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast

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12 December 2020

A ras-like protein is required for a post-Golgi event in yeast secretion

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12 December 2020

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

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12 December 2020

Parallel secretory pathways to the cell surface in yeast

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12 December 2020

Activation of Raf as a result of recruitment to the plasma membrane

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12 December 2020

Sec9 is a SNAP-25-like component of a yeast SNARE complex that may be the effector of Sec4 function in exocytosis

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12 December 2020

Rab GTPases: master regulators of membrane trafficking

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12 December 2020

Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

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12 December 2020

In vitro activity of 1,3-beta-D-glucan synthase requires the GTP-binding protein Rho1.

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12 December 2020

Elongation factor Tu, a GTPase triggered by codon recognition on the ribosome: mechanism and GTP consumption

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12 December 2020

A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae.

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12 December 2020

Genetic analysis of the Saccharomyces cerevisiae RHO3 gene, encoding a rho-type small GTPase, provides evidence for a role in bud formation

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12 December 2020

Physical association with ras enhances activation of membrane-bound raf (RafCAAX).

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12 December 2020

Analysis of a yeast SNARE complex reveals remarkable similarity to the neuronal SNARE complex and a novel function for the C terminus of the SNAP-25 homolog, Sec9.

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12 December 2020

GTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport

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12 December 2020

Regulation of SNARE complex assembly by an N-terminal domain of the t-SNARE Sso1p.

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12 December 2020

The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton

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12 December 2020

10.1016/J.TCB.2008.06.007

Identifiers

DOI

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30 June 2019

PMCID

6521695

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30 June 2019

PubMed ID

18706813

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30 June 2019