(Q37246024)

19 August 2017

1 reference

title

Addiction and dose response: the psychomotor stimulant theory of addiction reveals that hormetic dose responses are dominant (English)

1 reference

19 August 2017

Edward J Calabrese

1

1 reference

PubMed ID

18709568

19 August 2017

language of work or name

English

0 references

publication date

1 January 2008

1 reference

Critical Reviews in Toxicology

19 August 2017

1 reference

19 August 2017

38

1 reference

19 August 2017

7

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19 August 2017

599-617

1 reference

Effects of nicotine on the exploratory locomotion patterns of female Roman high- and low-avoidance rats

19 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Enhancement of cocaine-seeking behavior by repeated nicotine exposure in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Ethanol sleep times and hepatic alcohol and aldehyde dehydrogenase activities in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The effects of ethanol on the offense and defensive behaviors of male and female rats during group formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Paradigm lost, paradigm found: the re-emergence of hormesis as a fundamental dose response model in the toxicological sciences

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Hormesis: why it is important to toxicology and toxicologists

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The frequency of U-shaped dose responses in the toxicological literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Hormesis: U-shaped dose responses and their centrality in toxicology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Applications of hormesis in toxicology, risk assessment and chemotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Toxicology rethinks its central belief

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of chlordiazepoxide and ethanol on the extinction of a conditioned taste aversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Suppression by dopamine-agonists of the ethanol-induced stimulation of locomotor activity and brain dopamine synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in vivo using an inhibitor of the aromatic amino acid decarboxylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The effects of nicotine on locomotor activity in non-tolerant and tolerant rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Genetic influences on acute responses to nicotine and nicotine tolerance in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Genetic animal models in the study of alcoholism

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Genetic determinants of sensitivity to pentobarbital in inbred mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

GABAA/alpha1 receptor agonists and antagonists: effects on species-typical and heightened aggressive behavior after alcohol self-administration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Genetic analyses of the biphasic nature of the alcohol dose-response curve

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Stimulant and depressant properties of sedative-hypnotics in mice selectively bred for differential sensitivity to ethanol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The stimulant effects of caffeine on locomotor behaviour in mice are mediated through its blockade of adenosine A(2A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Genetic correlations among ethanol-related behaviors and neurotensin receptors in long sleep (LS) x short sleep (SS) recombinant inbred strains of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of nicotine and stress on locomotion in Sprague-Dawley and Long-Evans male and female rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Adolescent and adult male rats differ in sensitivity to nicotine's activity effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Repeated alcohol: behavioral sensitization and alcohol-heightened aggression in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Alcohol, allopregnanolone and aggression in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Memory enhancement: supra-additive effect of subcutaneous cholinergic drug combinations in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effect of some phosphodiesterase inhibitors on central dopamine mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

An evaluation of the locomotor stimulating action of ethanol in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Enhanced motor activity and brain dopamine turnover in mice during long-term nicotine administration in the drinking water

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of chronic oral nicotine treatment and its withdrawal on locomotor activity and brain monoamines in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The effect of nicotine on rearing in two strains of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Synergistic interactions between nicotine and cocaine or methylphenidate depend on the dose of dopamine transporter inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Analysis of the biphasic locomotor response to ethanol in high and low responders to novelty: a study in Nijmegen Wistar rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Psychotropic effects of caffeine in man. IV. Quantitative and qualitative differences associated with habituation to coffee.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The adenosine A1 receptor contributes to the stimulatory, but not the inhibitory effect of caffeine on locomotion: a study in mice lacking adenosine A1 and/or A2A receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Influences of genotype and sex on behavioral tolerance to nicotine in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of caffeine, methamphetamine and methylphenidate on reactions to novelty and activity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of cocaine, nicotine, dizocipline and alcohol on mice locomotor activity: cocaine-alcohol cross-sensitization involves upregulation of striatal dopamine transporter binding sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Motivated behaviors produced by increased arousal in the presence of goal objects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of Daily Cocaine and Morphine Treatment on Somatodendritic and Terminal Field Dopamine Release

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The effects of nicotine on locomotor activity and dopamine overflow in the alcohol-preferring AA and alcohol-avoiding ANA rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Chronic nicotine and locomotor activity: influences of exposure dose and test dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Exposure to nicotine enhances the behavioral stimulant effect of nicotine and increases binding of [3H]acetylcholine to nicotinic receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of 5-HT3, D1 and D2 receptor antagonists on ethanol- and cocaine-induced locomotion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Alteration of ethanol-induced changes in locomotor activity by adrenergic blockers in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Glucocorticoids are modulators of GABAA receptors in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Involvement of acetylcholine in the nucleus accumbens in cocaine reinforcement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of alcohol on attack and defensive-submissive reactions in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Neurosteroids, GABAA receptors, and escalated aggressive behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Pregnenolone sulfate antagonizes GABAA receptor-mediated currents via a reduction of channel opening frequency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Comparison of reticular and cochlear multiple unit activity with auditory evoked responses during various stages induced by anesthetic agents. II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The occurrence of tolerance to a central depressant effect of nicotine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

A comparison of morphine-induced locomotor activity and mesolimbic dopamine release in C57BL6, 129Sv and DBA2 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Phencyclidine-induced stereotyped behavior in rats: Dose response effects and antagonism by neuroleptics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The role of olfactory and orosensory factors in the alcohol preference of inbred strains of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of acute and chronic bupropion on locomotor activity and dopaminergic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Motor activity and alcohol: genetic analysis in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

A temporal and spatial scaling hypothesis for the behavioral effects of psychostimulants

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Repeated nicotine treatment in rats with high versus low rearing activity: analyses of behavioural sensitisation and place preference

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of alcohol and caffeine on wheel running activity in the Mongolian gerbil

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of acute and repeated ethanol exposures on the locomotor activity of BXD recombinant inbred mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The role of adenosine and its nucleotides in central synaptic transmission

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

A novel method to assess initial sensitivity and acute functional tolerance to hypnotic effects of ethanol

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Ethanol-induced mouse strain differences in locomotor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effect of bupropion on nicotine self-administration in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Adolescent and adult rats respond differently to nicotine and alcohol: motor activity and body temperature

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Brain area nicotine levels in male and female rats with different levels of spontaneous activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of nicotine on behavioral arousal and brain 5-Hydroxytryptamine function in female rats selected for differences in activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Nicotine intake and its regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Differential effects of nicotine and amphetamine on locomotor activity and maze exploration in two rat lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

A single gene difference determines relative susceptibility to caffeine-induced lethality in SWR and CBA inbred mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Interstrain variation in acute toxic response to caffeine among inbred mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The effects of NMDA and GABAA pharmacological manipulations on acute and rapid tolerance to ethanol during ontogeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Alkylxanthines: Inhibition of adenosine-elicited accumulation of cyclic AMP in brain slices and of brain phosphodiesterase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Behavioral and molecular actions of caffeine: focus on adenosine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Adenosine receptors and behavioral actions of methylxanthines

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of continuous oral nicotine administration on brain nicotinic receptors and responsiveness to nicotine in C57Bl/6 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Low dose effects in psychopharmacology: ontogenetic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

The influence of caffeine and theobromine on locomotive activity and the brain cGMP/cAMP ratio in white mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Divergent selection for pentobarbital-induced sleeping times in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Divergent selection for pentobarbital-induced sedation times in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Rat strain differences in open-field behavior and the locomotor stimulating and rewarding effects of amphetamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Physiological roles for adenosine and adenosine 5′-triphosphate in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Role of dopaminergic neurotransmission in locomotor stimulation by dexamphetamine and ethanol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Adenosine regulates via two different types of receptors, the accumulation of cyclic AMP in cultured brain cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Acute effects of ethanol on behavior of adolescent rats: role of social context

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Comparative behavioral characterization of the neuroactive steroids 3 alpha-OH,5 alpha-pregnan-20-one and 3 alpha-OH,5 beta-pregnan-20-one in rodents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Effects of cocaine on locomotor activity and schedule-controlled behaviors of inbred rat strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Nicotine and heroin augment cocaine-induced dopamine overflow in nucleus accumbens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

Universities rally against cuts in Pentagon-funded research

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F10408440802026315

10.1080/10408440802026315

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

18709568