(Q37252197)

English

Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activation

scientific article published on 08 April 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activation (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Haroldo A Toque

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Kenia P Nunes

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Lin Yao

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

James K Liao

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

R Clinton Webb

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Ruth B Caldwell

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

R William Caldwell

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

publication date

8 April 2013

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

number of pages

14

1 reference

based on heuristic

inferred from page(s)

The Journal of Sexual Medicine

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

10

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1502-1515

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Arginase II deletion increases corpora cavernosa relaxation in diabetic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

p38 Mitogen-activated protein kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II-treated mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Up-regulation of the RhoA/Rho-kinase signaling pathway in corpus cavernosum from endothelial nitric-oxide synthase (NOS), but not neuronal NOS, null mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Effects of p38 MAPK inhibition on early stages of diabetic retinopathy and sensory nerve function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Recent advances in arginine metabolism: roles and regulation of the arginases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Arginase: a critical regulator of nitric oxide synthesis and vascular function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Physiology of penile erection and pathophysiology of erectile dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

RhoA/Rho-kinase suppresses endothelial nitric oxide synthase in the penis: a mechanism for diabetes-associated erectile dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

p38 mitogen-activated protein kinase inhibitors for the treatment of chronic cardiovascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Pharmacology of penile erection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

6 September 2017

Inhibitors of p38 and ERK1/2 MAPkinase and hydrogen sulphide block constitutive and IL-1β-induced IL-6 and IL-8 expression in the human chondrocyte cell line C-28/I2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

14 September 2017

Pharmacological modulation of epithelial mesenchymal transition caused by angiotensin II. Role of ROCK and MAPK pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

14 September 2017

Phosphorylation of Thr695 and Thr850 on the myosin phosphatase target subunit: inhibitory effects and occurrence in A7r5 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

14 September 2017

Effects of systemic inhibition of Rho kinase on blood pressure and renal haemodynamics in diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

26 June 2018

Diabetes-induced coronary vascular dysfunction involves increased arginase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

26 June 2018

Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

26 June 2018

Chronic treatment with an oral rho-kinase inhibitor restores erectile function by suppressing corporal apoptosis in diabetic rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Interferon-gamma priming is involved in the activation of arginase by oligodeoxinucleotides containing CpG motifs in murine macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

NADPH oxidase activation: a mechanism of hypertension-associated erectile dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Elevated RhoA/Rho-kinase activity in the aged rat penis: mechanism for age-associated erectile dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Correction of nitrergic neurovascular dysfunction in diabetic mouse corpus cavernosum by p38 mitogen-activated protein kinase inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Arginase inhibition reduces endothelial dysfunction and blood pressure rising in spontaneously hypertensive rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Rho-kinase inhibition improves erectile function in aging male Brown-Norway rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway: implications for atherosclerotic endothelial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Arginase pathway in human endothelial cells in pathophysiological conditions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Effects of the Rho-kinase inhibitors, Y-27632 and fasudil, on the corpus cavernosum from diabetic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Increased contractility of diabetic rabbit corpora smooth muscle in response to endothelin is mediated via Rho-kinase beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Nitric oxide inhibits RhoA/Rho-kinase signaling to cause penile erection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Lysophosphatidylcholine induces apoptosis in human endothelial cells through a p38-mitogen-activated protein kinase-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Effect of Rho-kinase inhibition on vasoconstriction in the penile circulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Increased expression of arginase II in human diabetic corpus cavernosum: in diabetic-associated erectile dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide-mediated vasodilatory function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807104

3 September 2018

Abnormal protein expression in the corpus cavernosum impairs erectile function in type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23566117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23566117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human and rabbit cavernosal smooth muscle cells express Rho-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23566117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma amino acids in relation to metabolic control in insulin-dependent diabetic children

1 reference

https://pubmed.ncbi.nlm.nih.gov/23566117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23566117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma and vascular tissue arginine are decreased in diabetes: acute arginine supplementation restores endothelium-dependent relaxation by augmenting cGMP production

1 reference

https://pubmed.ncbi.nlm.nih.gov/23566117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of fasudil on macrovascular disorder-induced endothelial dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/23566117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23566117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of p38 MAPK Inhibitor on angiotensin II-dependent hypertension, organ damage, and superoxide anion production

1 reference

https://pubmed.ncbi.nlm.nih.gov/23566117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/JSM.12134

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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