(Q37252523)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19837906%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Clinical pharmacokinetics and exposure-toxicity relationship of a folate-Vinca alkaloid conjugate EC145 in cancer patients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19837906%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

0 references

1 reference

4

1 reference

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10 February 2020

author name string

Jing Li

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19837906%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

Edward A Sausville

2

1 reference

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10 February 2020

Patrick J Klein

3

1 reference

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10 February 2020

Christopher P Leamon

5

1 reference

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10 February 2020

Richard A Messmann

6

1 reference

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10 February 2020

Patricia LoRusso

7

1 reference

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10 February 2020

publication date

16 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19837906%20AND%20SRC:MED&resulttype=core&format=json

The Journal of Clinical Pharmacology

10 February 2020

published in

1 reference

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10 February 2020

volume

49

1 reference

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10 February 2020

issue

12

1 reference

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10 February 2020

page(s)

1467-1476

1 reference

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Preclinical antitumor activity of a novel folate-targeted dual drug conjugate

10 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Synthesis and biological evaluation of EC72: a new folate-targeted chemotherapeutic

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Folate receptor expression in carcinomas and normal tissues determined by a quantitative radioligand binding assay

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Synthesis and biological evaluation of EC20: a new folate-derived, (99m)Tc-based radiopharmaceutical

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Overexpression of folate binding protein in ovarian cancers.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

The folate receptor in central nervous system malignancies of childhood

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

The biological chemistry of folate receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Targeting the folate receptor (FR): imaging and cytotoxicity of ReI conjugates in FR-overexpressing cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Clinical pharmacokinetics of irinotecan and its metabolites in relation with diarrhea

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807256

Xpose--an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19837906

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Design and regioselective synthesis of a new generation of targeted chemotherapeutics. Part 1: EC145, a folic acid conjugate of desacetylvinblastine monohydrazide

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19837906

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CYP3A phenotyping approach to predict systemic exposure to EGFR tyrosine kinase inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19837906

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1177/0091270009339740

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19837906%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19837906%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

19837906

1 reference