(Q37253000)

19 August 2017

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title

HMG-CoA reductase inhibitors: do they have potential in the treatment of polycystic ovary syndrome? (English)

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polycystic ovary syndrome

19 August 2017

main subject

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Pinar H Kodaman

1

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19 August 2017

Antoni J Duleba

series ordinal

2

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19 August 2017

publication date

1 January 2008

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19 August 2017

number of pages

15

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inferred from page(s)

published in

Drugs

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19 August 2017

volume

68

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19 August 2017

issue

13

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19 August 2017

page(s)

1771-1785

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https://scigraph.springernature.com/pub.10.2165/00003495-200868130-00001

19 August 2017

exact match

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Relationship between androgen levels and blood pressure in young women with polycystic ovary syndrome.

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Obesity and insulin resistance but not hyperandrogenism mediates vascular dysfunction in women with polycystic ovary syndrome

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Lipoprotein lipid concentrations and cardiovascular risk in women with polycystic ovary syndrome

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12 December 2020

Effects of insulin and insulin-like growth factors on proliferation of rat ovarian theca-interstitial cells

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12 December 2020

Screening for abnormal glucose tolerance in adolescents with polycystic ovary syndrome

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12 December 2020

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12 December 2020

The role of insulin-like growth factor-1 (IGF-1) and IGF binding protein-1 (IGFBP-1) in the pathogenesis of polycystic ovary syndrome

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12 December 2020

Insulin stimulates androgen accumulation in incubations of human ovarian stroma and theca.

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12 December 2020

Pregnancy complications in women with polycystic ovary syndrome.

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12 December 2020

Enhanced mitogenic signaling in skeletal muscle of women with polycystic ovary syndrome.

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12 December 2020

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12 December 2020

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12 December 2020

The plasma homocysteine levels are increased in polycystic ovary syndrome

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12 December 2020

Role of ERK in hydrogen peroxide-induced cell death of human glioma cells.

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12 December 2020

Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women

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12 December 2020

Cerivastatin improves survival of mice with lipopolysaccharide-induced sepsis

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12 December 2020

Mevastatin inhibits ovarian theca-interstitial cell proliferation and steroidogenesis

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12 December 2020

The effects of rosiglitazone and metformin on oxidative stress and homocysteine levels in lean patients with polycystic ovary syndrome

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12 December 2020

Exercise decreases plasma total homocysteine in overweight young women with polycystic ovary syndrome

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12 December 2020

Polycystic ovary syndrome and endometrial carcinoma

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12 December 2020

Low grade chronic inflammation in women with polycystic ovarian syndrome

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12 December 2020

Cellular antioxidant effects of atorvastatin in vitro and in vivo

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12 December 2020

Vascular cell adhesion molecule-1: a viable therapeutic target for atherosclerosis?

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12 December 2020

Polycystic ovary syndrome is associated with endothelial dysfunction

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12 December 2020

Effect of alternative glycosylation on insulin receptor processing

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12 December 2020

Diverse effects of inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase on the expression of VCAM-1 and E-selectin in endothelial cells

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12 December 2020

Tumor necrosis factor induced oxidative stress in isolated mouse hepatocytes

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12 December 2020

Simvastatin induces apoptosis of cultured rat cardiomyocytes

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12 December 2020

The increase of leukocytes as a new putative marker of low-grade chronic inflammation and early cardiovascular risk in polycystic ovary syndrome

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12 December 2020

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12 December 2020

Obesity as an independent risk factor for infectious morbidity in patients who undergo cesarean delivery

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12 December 2020

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12 December 2020

Relationship between serum lipoprotein ratios and insulin resistance in obesity

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12 December 2020

Effects of insulin on steroidogenesis in cultured porcine ovarian theca

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12 December 2020

Effects of high-dose simvastatin on adrenal and gonadal steroidogenesis in men with hypercholesterolemia

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12 December 2020

Young obese women with polycystic ovary syndrome have evidence of early coronary atherosclerosis.

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12 December 2020

Suppression of serum insulin by diazoxide reduces serum testosterone levels in obese women with polycystic ovary syndrome

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12 December 2020

Metabolic profiles and lipoprotein lipid concentrations in non-obese and obese patients with polycystic ovarian disease

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12 December 2020

Screening women with polycystic ovary syndrome for metabolic syndrome

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12 December 2020

Cardiovascular disease risk factors in polycystic ovary syndrome

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

In vitro fertilization in the polycystic ovary syndrome patient: an update.

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12 December 2020

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12 December 2020

Stimulation of low-density lipoprotein oxidation by insulin and insulin like growth factor I

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12 December 2020

Insulin and insulin-like growth factor I stimulate the proliferation of human ovarian theca-interstitial cells

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12 December 2020

Effect of flutamide and metformin administered alone or in combination in dieting obese women with polycystic ovary syndrome

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12 December 2020

Elevated serum levels of free insulin-like growth factor I in polycystic ovary syndrome.

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12 December 2020

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12 December 2020

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12 December 2020

Suppression of hyperandrogenism does not improve peripheral or hepatic insulin resistance in the polycystic ovary syndrome

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12 December 2020

Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome.

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12 December 2020

Familial clustering in the polycystic ovarian syndrome

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12 December 2020

Inappropriate Secretion of Follicle-Stimulating Hormone and Luteinizing Hormone in Polycystic Ovarian Disease

1 reference

12 December 2020

Proliferation of ovarian theca-interstitial cells is modulated by antioxidants and oxidative stress

1 reference

12 December 2020

Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status

1 reference

12 December 2020

Human fat cells possess a plasma membrane-bound H2O2-generating system that is activated by insulin via a mechanism bypassing the receptor kinase

1 reference

12 December 2020

The effect of a pure antiandrogen receptor blocker, flutamide, on the lipid profile in the polycystic ovary syndrome

1 reference

12 December 2020

3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy

1 reference

12 December 2020

Effect of alpha-tocopherol and silibin dihemisuccinate on the proliferation of human skin fibroblasts

1 reference

12 December 2020

Homocysteine and steroids levels in metformin treated women with polycystic ovary syndrome.

1 reference

12 December 2020

Association between polycystic ovaries and extent of coronary artery disease in women having cardiac catheterization

1 reference

12 December 2020

A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphory

1 reference

12 December 2020

Influence of serum luteinising hormone concentrations on ovulation, conception, and early pregnancy loss in polycystic ovary syndrome

1 reference

12 December 2020

Polycystic ovary syndrome and risk for myocardial infarction. Evaluated from a risk factor model based on a prospective population study of women

1 reference

12 December 2020

The metabolic syndrome in women

1 reference

12 December 2020

Postmenopausal women with a history of irregular menses and elevated androgen measurements at high risk for worsening cardiovascular event-free survival: results from the National Institutes of Health--National Heart, Lung, and Blood Institute spons

1 reference

12 December 2020

A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome

1 reference

12 December 2020

Primary and secondary prevention of atherosclerosis: is there a role for antioxidants?

1 reference

12 December 2020

Localization of androgen receptors in human skin by immunohistochemistry: implications for the hormonal regulation of hair growth, sebaceous glands and sweat glands

1 reference

12 December 2020

The association between polycystic ovaries and endometrial cancer

1 reference

12 December 2020

Epidemiology of infertility and polycystic ovarian disease: endocrinological and demographic studies

1 reference

12 December 2020

1 reference

12 December 2020

Interaction between the insulin receptor and its downstream effectors. Use of individually expressed receptor domains for structure/function analysis

1 reference

12 December 2020

Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome

1 reference

12 December 2020

Insulin's stimulation of endothelial superoxide generation may reflect up-regulation of isoprenyl transferase activity that promotes rac translocation

1 reference

12 December 2020

Polycystic ovaries and ovarian hyperstimulation syndrome: a systematic review*.

1 reference

12 December 2020

Low levels of low molecular weight insulin-like growth factor-binding protein in patients with polycystic ovarian disease

1 reference

12 December 2020

Pregnancy complications and outcomes among overweight and obese nulliparous women

1 reference

12 December 2020

Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline

1 reference

12 December 2020

Elevated serum levels of tumor necrosis factor alpha in normal-weight women with polycystic ovary syndrome

1 reference

12 December 2020

Effects of simvastatin and oral contraceptive agent on polycystic ovary syndrome: prospective, randomized, crossover trial

1 reference

12 December 2020

Plasma levels of insulin-like growth factor-I and its binding protein in polycystic ovary syndrome.

1 reference

12 December 2020

Risk of multiple gestation after ovulation induction in polycystic ovary syndrome

1 reference

12 December 2020

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1 reference

12 December 2020

Proliferation and differentiation of rat theca-interstitial cells: comparison of effects induced by platelet-derived growth factor and insulin-like growth factor-I

1 reference

12 December 2020

Effects of cerivastatin on human arterial smooth muscle cell proliferation and migration in transfilter cocultures

1 reference

12 December 2020

Hyperhomocysteinemia: an independent risk factor for vascular disease

1 reference

12 December 2020

Obstetric outcomes associated with increase in BMI category during pregnancy

1 reference

12 December 2020

Specific glycosylation site mutations of the insulin receptor alpha subunit impair intracellular transport

1 reference

12 December 2020

Ascorbate affects proliferation of guinea-pig vascular smooth muscle cells by direct and extracellular matrix-mediated effects

1 reference

12 December 2020

The genetics of the polycystic ovary syndrome

1 reference

12 December 2020

Banting lecture 1988. Role of insulin resistance in human disease

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12 December 2020

Effects of race and family history of type 2 diabetes on metabolic status of women with polycystic ovary syndrome

1 reference

12 December 2020

Cardiovascular consequences of polycystic ovary syndrome

1 reference

12 December 2020

Divergent mechanisms regulate proliferation/survival and steroidogenesis of theca-interstitial cells

1 reference

12 December 2020

Risk factors for coronary artery disease in lean and obese women with the polycystic ovary syndrome.

1 reference

12 December 2020

Oxidative stress in polycystic ovary syndrome and its contribution to the risk of cardiovascular disease

1 reference

12 December 2020

Recurrent early miscarriage and polycystic ovaries

1 reference

12 December 2020

Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome

1 reference

12 December 2020

Selective insulin resistance in the polycystic ovary syndrome

1 reference

12 December 2020

Mortality of women with polycystic ovary syndrome at long-term follow-up

1 reference

12 December 2020

Prediction of coronary events with electron beam computed tomography

1 reference

12 December 2020

Treatment of hirsutism and acne in hyperandrogenism

1 reference

12 December 2020

Maternal outcomes in pregnancies complicated by obesity.

1 reference

12 December 2020

Circulating gonadotropins, estrogens, and androgens in polycystic ovarian disease

1 reference

12 December 2020

The molecular basis for oxidative stress-induced insulin resistance

1 reference

12 December 2020

10.2165/00003495-200868130-00001

Identifiers

DOI

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Dimensions Publication ID

19 August 2017

1000058746

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1 reference