(Q37253693)

19 August 2017

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title

Comparative modeling of proteins in the design of novel renin inhibitors (English)

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19 August 2017

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Hutchins C

1

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19 August 2017

Greer J

series ordinal

2

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19 August 2017

publication date

1 January 1991

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Critical Reviews in Biochemistry and Molecular Biology

19 August 2017

published in

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19 August 2017

volume

26

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19 August 2017

issue

1

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19 August 2017

page(s)

77-127

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Recent developments in the design of angiotensin-converting enzyme inhibitors

19 August 2017

cites work

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Structure of human renin and expression of the renin gene

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Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution

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Stereochemical analysis of peptide bond hydrolysis catalyzed by the aspartic proteinase penicillopepsin

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Conformational flexibility in the active sites of aspartyl proteinases revealed by a pepstatin fragment binding to penicillopepsin

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Energy calculations on aspartic proteinases: human renin, endothiapepsin and its complex with an angiotensinogen fragment analogue, H-142.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Structure and refinement of penicillopepsin at 1.8 Å resolution

21 January 2018

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21 January 2018

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Potent new inhibitors of human renin

21 January 2018

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Antigenic determinants in proteins coincide with surface regions accessible to large probes (antibody domains).

21 January 2018

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21 January 2018

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Functional characterization of Asp-317 mutant of human renin expressed in COS cells

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21 January 2018

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21 January 2018

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Renin inhibitors. Design of angiotensinogen transition-state analogues containing novel. (2R,3R,4R,5S)-5-amino-3,4-dihydroxy-2-isopropyl-7-methyloctanoic acid

21 January 2018

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Renin inhibitors. Syntheses of subnanomolar, competitive, transition-state analogue inhibitors containing a novel analogue of statine

21 January 2018

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21 January 2018

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Renin inhibitors. Design and synthesis of a new class of conformationally restricted analogues of angiotensinogen.

21 January 2018

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Structure refinement of a cyclic peptide from two-dimensional NMR data and molecular modeling

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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10 June 2024

Identifiers

DOI

10.3109/10409239109081721

1 reference

19 August 2017

1 reference