(Q37256842)

19 August 2017

1 reference

title

Targeting the endothelin system: novel therapeutic options in gynecological, urological and breast cancers (English)

1 reference

19 August 2017

Martin Smollich

1

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19 August 2017

Pia Wülfing

series ordinal

2

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19 August 2017

publication date

1 September 2008

1 reference

Expert Review of Anticancer Therapy

19 August 2017

published in

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19 August 2017

volume

8

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19 August 2017

issue

9

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19 August 2017

page(s)

1481-1493

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The endothelin axis: emerging role in cancer

19 August 2017

cites work

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21 January 2018

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The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes

21 January 2018

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Cloning and expression of a cDNA encoding an endothelin receptor

21 January 2018

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Molecular characterization of endothelin receptors

21 January 2018

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Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

21 January 2018

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Human endothelial cell storage granules: a novel intracellular site for isoforms of the endothelin-converting enzyme

21 January 2018

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Immunocytochemical localization of endothelin in cultured bovine endothelial cells

21 January 2018

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Rapid degradation of endothelin-1 by an enzyme released by the rat isolated perfused mesentery

21 January 2018

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Endothelins as cardiovascular peptides

21 January 2018

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Pathophysiology of endothelin in the cardiovascular system

21 January 2018

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Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells

21 January 2018

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Endothelin-1 inhibits apoptosis in prostate cancer

21 January 2018

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Mechanism of endothelin-1 activation of MAP kinases in neonatal pulmonary vascular smooth muscle

21 January 2018

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Stimulatory interaction between vascular endothelial growth factor and endothelin-1 on each gene expression

21 January 2018

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Vasoactive peptides modulate vascular endothelial cell growth factor production and endothelial cell proliferation and invasion

21 January 2018

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21 January 2018

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Hypoxia regulates expression of the endothelin-1 gene through a proximal hypoxia-inducible factor-1 binding site on the antisense strand

21 January 2018

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Regulation of endothelin-1 gene expression in human microvascular endothelial cells by hypoxia and cobalt: role of hypoxia responsive element

21 January 2018

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Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells.

21 January 2018

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21 January 2018

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Inhibitory effect of endothelin A receptor blockade on tumor growth and liver metastasis of a human gastric cancer cell line

21 January 2018

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21 January 2018

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21 January 2018

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A reversible radioligand specific for the ETB receptor: [125I]Tyr13-Suc-[Glu9,Ala11,15]-endothelin-1(8–21), [125I]IRL 1620

21 January 2018

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Endothelin-converting enzyme-1 inhibition and growth of human glioblastoma cells.

21 January 2018

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The peptidase inhibitor CGS-26303 increases endothelin converting enzyme-1 expression in endothelial cells through accumulation of big endothelin-1

21 January 2018

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Endothelin-1 protects ovarian carcinoma cells against paclitaxel-induced apoptosis: requirement for Akt activation

21 January 2018

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Role of endothelin-1 in neovascularization of ovarian carcinoma

21 January 2018

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ZD4054, a specific antagonist of the endothelin A receptor, inhibits tumor growth and enhances paclitaxel activity in human ovarian carcinoma in vitro and in vivo

21 January 2018

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The epidemiology of cervical cancer

21 January 2018

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Human papillomaviruses and cervical cancer

21 January 2018

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Expression of endothelin 1 and endothelin A receptor in HPV-associated cervical carcinoma: new potential targets for anticancer therapy

21 January 2018

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Targeting endothelin receptor type A in human cervical carcinoma cells.

21 January 2018

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Anti-progressive effect of neutral endopeptidase 24.11 (NEP/CD10) on cervical carcinoma in vitro and in vivo

21 January 2018

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Decreased expression of messenger RNAs encoding endothelin receptors and neutral endopeptidase 24.11 in endometrial cancer

21 January 2018

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Human endometrial adenocarcinoma cells express endothelin-1.

21 January 2018

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https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Endothelin converting enzyme-1 expression in endometrial adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Hypoxia induces endothelin gene expression and secretion in cultured human endothelium

21 January 2018

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Evidence for the involvement of ET(B) receptors in ET-1-induced changes in blood flow to the rat breast tumor

21 January 2018

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Expression of endothelins and their receptors promotes an invasive phenotype of breast tumor cells but is insufficient to induce invasion in benign cells

21 January 2018

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Selective ETAR antagonist atrasentan inhibits hypoxia-induced breast cancer cell invasion

21 January 2018

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A role for endothelin-2 and its receptors in breast tumor cell invasion

21 January 2018

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Effect of endothelin-A receptor blockade with atrasentan on tumor progression in men with hormone-refractory prostate cancer: a randomized, phase II, placebo-controlled trial

21 January 2018

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Role of endothelin-1 in osteoblastic bone metastases

21 January 2018

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A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases

21 January 2018

1 reference

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Bosentan inhibits tumor vascularization and bone metastasis in an immunocompetent skin-fold chamber model of breast carcinoma cell metastasis.

21 January 2018

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On the role of endothelin-converting enzyme-1 (ECE-1) and neprilysin in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Endothelin B receptor agonist, IRL 1620, enhances the anti-tumor efficacy of paclitaxel in breast tumor rats

21 January 2018

1 reference

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21 January 2018

Cancer statistics, 2008

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https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Osteoblasts in prostate cancer metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Endothelin-1 and osteoblastic metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Endothelin Inhibition: Novel Therapy for Prostate Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Stromal-epithelial interactions influence prostate cancer cell invasion by altering the balance of metallopeptidase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

New bone formation in an osteoblastic tumor model is increased by endothelin-1 overexpression and decreased by endothelin A receptor blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

ETA receptor mediates the signaling of endothelin-1 in osteoblast-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

In vitro and in vivo molecular evidence for better therapeutic efficacy of ABT-627 and taxotere combination in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Endothelin receptor A blockade enhances taxane effects in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Inhibitory effects of a selective endothelin-A receptor antagonist YM598 on endothelin-1-induced potentiation of nociception in formalin-induced and prostate cancer-induced pain models in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Potentiation of 2-methoxyestradiol-induced cytotoxicity by blocking endothelin A receptor in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Lentiviral vector neutral endopeptidase gene transfer suppresses prostate cancer tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Prognostic factors and clinical trials of new agents in patients with metastatic renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Endothelins in the urinary tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Endothelin axis expression is markedly different in the two main subtypes of renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Endothelin-1 promotes cell survival in renal cell carcinoma through the ET(A) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

The endothelin receptor blocker bosentan inhibits doxorubicin-induced cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Peripheral endothelin A receptor antagonism attenuates carcinoma-induced pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

Stimulation of colorectal cancer cell line growth by ET-1 and its inhibition by ET(A) antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14737140.8.9.1481

10.1586/14737140.8.9.1481

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference