Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q37257366)
Watch
English
Ligand-specific conformational changes in the alpha1 glycine receptor ligand-binding domain
scientific article published on 13 March 2009
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
title
Ligand-specific conformational changes in the alpha1 glycine receptor ligand-binding domain
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
main subject
ligand binding
1 reference
based on heuristic
inferred from title
author
Stephan A. Pless
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
author name string
Joseph W Lynch
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
language of work or name
English
0 references
publication date
13 March 2009
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
published in
Journal of Biological Chemistry
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
volume
284
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
issue
23
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
page(s)
15847-15856
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
cites work
Distinct structural changes in the GABAA receptor elicited by pentobarbital and GABA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Structural rearrangements in loop F of the GABA receptor signal ligand binding, not channel activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
A cation-pi interaction in the binding site of the glycine receptor is mediated by a phenylalanine residue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
A conserved salt bridge critical for GABA(A) receptor function and loop C dynamics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Illuminating the structure and function of Cys-loop receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Mechanics of channel gating of the nicotinic acetylcholine receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Implications of the quaternary twist allosteric model for the physiology and pathology of nicotinic acetylcholine receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Targeted molecular dynamics study of C-loop closure and channel gating in nicotinic receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Recent advances in Cys-loop receptor structure and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
A unified view of the role of electrostatic interactions in modulating the gating of Cys loop receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Initial coupling of binding to gating mediated by conserved residues in the muscle nicotinic receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
A gating mechanism proposed from a simulation of a human alpha7 nicotinic acetylcholine receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
The beta subunit determines the ligand binding properties of synaptic glycine receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Refined structure of the nicotinic acetylcholine receptor at 4A resolution
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Cys-loop receptors: new twists and turns
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Structural elements involved in activation of the gamma-aminobutyric acid type A (GABAA) receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Structure and action of the nicotinic acetylcholine receptor explored by electron microscopy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Role of charged residues in coupling ligand binding and channel activation in the extracellular domain of the glycine receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Kinetic determinants of agonist action at the recombinant human glycine receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Coupling of agonist binding to channel gating in the GABA(A) receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Openings of the rat recombinant alpha 1 homomeric glycine receptor as a function of the number of agonist molecules bound
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
The Ligand Gated Ion Channel database: an example of a sequence database in neuroscience
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding element
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
The glycine synaptic receptor: evidence that strychnine binding is associated with the ionic conductance mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Strychnine binding associated with glycine receptors of the central nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Receptor classes and the transmitter-gated ion channels
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
Distinct agonist- and antagonist-binding sites on the glycine receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
6 September 2017
The F-loop of the GABA A receptor gamma2 subunit contributes to benzodiazepine modulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
14 September 2017
Mutagenesis and molecular modeling reveal the importance of the 5-HT3 receptor F-loop
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
14 September 2017
Agonist- and antagonist-induced conformational changes of loop F and their contributions to the rho1 GABA receptor function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
26 June 2018
Acetylcholine receptor gating: movement in the alpha-subunit extracellular domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
26 June 2018
Evaluation of a proposed mechanism of ligand-gated ion channel activation in the GABAA and glycine receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
26 June 2018
Charged Residues in the β2 Subunit Involved in GABAA Receptor Activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
26 June 2018
Distinct conformational changes in activated agonist-bound and agonist-free glycine receptor subunits
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Agonist- and competitive antagonist-induced movement of loop 5 on the alpha subunit of the neuronal alpha4beta4 nicotinic acetylcholine receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Conformational variability of the glycine receptor M2 domain in response to activation by different agonists
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
An intersubunit trigger of channel gating in the muscle nicotinic receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Mapping conformational changes of a type IIb Na+/Pi cotransporter by voltage clamp fluorometry.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Local and global ligand-induced changes in the structure of the GABA(A) receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Channel opening motion of alpha7 nicotinic acetylcholine receptor as suggested by normal mode analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Principal pathway coupling agonist binding to channel gating in nicotinic receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Charged amino acids of the N-terminal domain are involved in coupling binding and gating in alpha7 nicotinic receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
The GABAA receptor alpha 1 subunit Pro174-Asp191 segment is involved in GABA binding and channel gating
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Site-specific fluorescence reveals distinct structural changes with GABA receptor activation and antagonism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2708881
retrieved
3 September 2018
Identifiers
DOI
10.1074/JBC.M809343200
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
PMC publication ID
2708881
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
PubMed publication ID
19286654
1 reference
stated in
Europe PubMed Central
PMC publication ID
2708881
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19286654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
23 January 2020
ResearchGate publication ID
24201240
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit