(Q37263636)

19 August 2017

1 reference

title

Galactose metabolism in yeast-structure and regulation of the leloir pathway enzymes and the genes encoding them (English)

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19 August 2017

author name string

Christopher A Sellick

series ordinal

1

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19 August 2017

Robert N Campbell

series ordinal

2

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19 August 2017

Richard J Reece

series ordinal

3

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19 August 2017

publication date

1 January 2008

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International Review of Cell and Molecular Biology

19 August 2017

published in

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19 August 2017

volume

269

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19 August 2017

page(s)

111-150

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A new yeast metabolon involving at least the two first enzymes of arginine biosynthesis: acetylglutamate synthase activity requires complex formation with acetylglutamate kinase

19 August 2017

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Epimerases: structure, function and mechanism

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The galactose switch in Kluyveromyces lactis depends on nuclear competition between Gal4 and Gal1 for Gal80 binding.

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Perinuclear localization of chromatin facilitates transcriptional silencing

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7 January 2021

A transcriptional activating region with two contrasting modes of protein interaction

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7 January 2021

Yeast regulatory gene GAL3: carbon regulation; UASGal elements in common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; encoded protein strikingly similar to yeast and Escherichia coli galactokinases

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7 January 2021

Overproduction of the GAL1 or GAL3 Protein Causes Galactose-Independent Activation of the GAL4 Protein: Evidence for a New Model of Induction for the Yeast GAL/MEL Regulon

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7 January 2021

SAGA is an essential in vivo target of the yeast acidic activator Gal4p

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7 January 2021

In vivo target of a transcriptional activator revealed by fluorescence resonance energy transfer

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7 January 2021

Novel Gal3 proteins showing altered Gal80p binding cause constitutive transcription of Gal4p-activated genes in Saccharomyces cerevisiae

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7 January 2021

Dependence of lactose metabolism upon mutarotase encoded in the gal operon in Escherichia coli

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7 January 2021

The histidine triad superfamily of nucleotide-binding proteins

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7 January 2021

Glucose repression of LAC gene expression in yeast is mediated by the transcriptional activator LAC9

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7 January 2021

Gene recruitment of the activated INO1 locus to the nuclear membrane

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7 January 2021

H2A.Z-mediated localization of genes at the nuclear periphery confers epigenetic memory of previous transcriptional state

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7 January 2021

Galactose regulation in Saccharomyces cerevisiae. The enzymes encoded by the GAL7, 10, 1 cluster are co-ordinately controlled and separately translated

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7 January 2021

Independent recruitment in vivo by Gal4 of two complexes required for transcription

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7 January 2021

SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope

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7 January 2021

Gal80 confers specificity on HAT complex interactions with activators

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7 January 2021

Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization

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7 January 2021

Characterization of the cytoplasm of Escherichia coli K-12 as a function of external osmolarity. Implications for protein-DNA interactions in vivo

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7 January 2021

Subcellular localization of galactose-1-phosphate uridylyltransferase in the yeast Saccharomyces cerevisiae

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7 January 2021

Molecular cloning, characterization, and mapping of a full-length cDNA encoding human UDP-galactose 4'-epimerase

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7 January 2021

Galactokinase of Vicia faba seeds

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7 January 2021

Cotranscriptional recruitment to the mRNA export receptor Mex67p contributes to nuclear pore anchoring of activated genes

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7 January 2021

The Spt components of SAGA facilitate TBP binding to a promoter at a post-activator-binding step in vivo

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7 January 2021

Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4.

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7 January 2021

The molecular biology of galactosemia

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7 January 2021

Molecular architecture of the yeast nuclear pore complex: localization of Nsp1p subcomplexes

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7 January 2021

The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II.

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7 January 2021

A novel genetic system to detect protein-protein interactions

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7 January 2021

The mRNA export machinery requires the novel Sac3p-Thp1p complex to dock at the nucleoplasmic entrance of the nuclear pores

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7 January 2021

Purification and mechanism of action of a plant galactokinase

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7 January 2021

The Leloir pathway: a mechanistic imperative for three enzymes to change the stereochemical configuration of a single carbon in galactose.

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7 January 2021

Mutations that increase the activity of a transcriptional activator in yeast and mammalian cells

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7 January 2021

The Tup1 corepressor directs Htz1 deposition at a specific promoter nucleosome marking the GAL1 gene for rapid activation

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7 January 2021

Recruitment of a 19S proteasome subcomplex to an activated promoter

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7 January 2021

The C-terminal domain of myosin-like protein 1 (Mlp1p) is a docking site for heterogeneous nuclear ribonucleoproteins that are required for mRNA export

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7 January 2021

Regulated expression of the GAL4 activator gene in yeast provides a sensitive genetic switch for glucose repression

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7 January 2021

Variant histone H2A.Z is globally localized to the promoters of inactive yeast genes and regulates nucleosome positioning

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7 January 2021

Kinetic studies of Escherichia coli galactokinase

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7 January 2021

Induction of the gal pathway and cellulase genes involves no transcriptional inducer function of the galactokinase in Hypocrea jecorina

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7 January 2021

GAL4 Is Regulated by the RNA Polymerase II Holoenzyme–Associated Cyclin-Dependent Protein Kinase SRB10/CDK8

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7 January 2021

Gene duplication and the adaptive evolution of a classic genetic switch

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7 January 2021

Structure and function of enzymes of the Leloir pathway for galactose metabolism

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7 January 2021

Galactokinase: structure, function and role in type II galactosemia

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7 January 2021

Structural Basis for Dimerization in DNA Recognition by Gal4

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7 January 2021

The Enzymatically Catalyzed Mutarotation. The Mechanism of Action of Mutarotase (Aldose 1-Epimerase) from Escherichia coli

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7 January 2021

Evidence that Gal11 protein is a target of the Gal4 activation domain in the mediator

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7 January 2021

Biofilm formation of Candida albicans is variably affected by saliva and dietary sugars

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7 January 2021

Multiple mechanisms provide rapid and stringent glucose repression of GAL gene expression in Saccharomyces cerevisiae

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7 January 2021

Remodeling hexose-1-phosphate uridylyltransferase: mechanism-inspired mutation into a new enzyme, UDP-hexose synthase

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7 January 2021

6-phosphogluconate dehydrogenase and glucose-6-phosphate dehydrogenase form a supramolecular complex in human neutrophils that undergoes retrograde trafficking during pregnancy

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7 January 2021

The structure of glucose-fructose oxidoreductase from Zymomonas mobilis: an osmoprotective periplasmic enzyme containing non-dissociable NADP

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7 January 2021

Mlp2p, a component of nuclear pore attached intranuclear filaments, associates with nic96p.

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7 January 2021

SWI/SNF is required for transcriptional memory at the yeast GAL gene cluster

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7 January 2021

The S. cerevisiae SAGA complex functions in vivo as a coactivator for transcriptional activation by Gal4.

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7 January 2021

The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators.

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7 January 2021

Nondissociation of GAL4 and GAL80 in vivo after galactose induction

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7 January 2021

Genetic evidence that an activation domain of GAL4 does not require acidity and may form a beta sheet

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7 January 2021

Phosphorylation of Zn(II)2Cys6 proteins: a cause or effect of transcriptional activation?

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7 January 2021

Transcriptional regulation in the yeast GAL gene family: a complex genetic network

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7 January 2021

Interaction of GAL4 and GAL80 gene regulatory proteins in vitro

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7 January 2021

Actively transcribed GAL genes can be physically linked to the nuclear pore by the SAGA chromatin modifying complex

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7 January 2021

The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80

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7 January 2021

A fungal family of transcriptional regulators: the zinc cluster proteins

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7 January 2021

UDPgalactose 4-epimerase from Saccharomyces cerevisiae. A bifunctional enzyme with aldose 1-epimerase activity

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7 January 2021

DNA recognition by GAL4: structure of a protein-DNA complex.

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7 January 2021

Transcriptional rewiring of fungal galactose-metabolism circuitry

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7 January 2021

Transcriptional activation domains of the Candida albicans Gcn4p and Gal4p homologs

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7 January 2021

Mutational hypersensitivity of a gene regulatory protein: Saccharomyces cerevisiae Gal80p

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7 January 2021

Conserved Histone Variant H2A.Z Protects Euchromatin from the Ectopic Spread of Silent Heterochromatin

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7 January 2021

Sites for interaction between Gal80p and Gal1p in Kluyveromyces lactis: structural model of galactokinase based on homology to the GHMP protein family.

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7 January 2021

Galactokinase encoded by GAL1 is a bifunctional protein required for induction of the GAL genes in Kluyveromyces lactis and is able to suppress the gal3 phenotype in Saccharomyces cerevisiae

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7 January 2021

The F box protein Dsg1/Mdm30 is a transcriptional coactivator that stimulates Gal4 turnover and cotranscriptional mRNA processing

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7 January 2021

Control of yeast GAL genes by MIG1 repressor: a transcriptional cascade in the glucose response

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7 January 2021

Old pathway--new concept: control of glycolysis by metabolite-modulated dynamic enzyme associations

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7 January 2021

The Snf1 kinase controls glucose repression in yeast by modulating interactions between the Mig1 repressor and the Cyc8-Tup1 co-repressor

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7 January 2021

A transcriptionally active form of GAL4 is phosphorylated and associated with GAL80

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7 January 2021

Evidence for Gal3p's cytoplasmic location and Gal80p's dual cytoplasmic-nuclear location implicates new mechanisms for controlling Gal4p activity in Saccharomyces cerevisiae

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7 January 2021

Gene activation by interaction of an inhibitor with a cytoplasmic signaling protein

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7 January 2021

Gal80 dimerization and the yeast GAL gene switch

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7 January 2021

The yeast galactose genetic switch is mediated by the formation of a Gal4p-Gal80p-Gal3p complex

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7 January 2021

The insertion of two amino acids into a transcriptional inducer converts it into a galactokinase

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7 January 2021

On the use of the word 'epigenetic'.

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7 January 2021

Targets of the Gal4 transcription activator in functional transcription complexes.

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7 January 2021

Relationship between genotype, activity, and galactose sensitivity in yeast expressing patient alleles of human galactose-1-phosphate uridylyltransferase

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7 January 2021

Sus1, a functional component of the SAGA histone acetylase complex and the nuclear pore-associated mRNA export machinery

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7 January 2021

Activating regions of yeast transcription factors must have both acidic and hydrophobic amino acids

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7 January 2021

Galactose-1-phosphate uridylyltransferase from Escherichia coli, a zinc and iron metalloenzyme.

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7 January 2021

GAL4 is phosphorylated as a consequence of transcriptional activation

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7 January 2021

Phosphorylation of Ga14p at a single C-terminal residue is necessary for galactose-inducible transcription

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7 January 2021

Analysis of the Kluyveromyces lactis positive regulatory gene LAC9 reveals functional homology to, but sequence divergence from, the Saccharomyces cerevisiae GAL4 gene

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7 January 2021

Nup-PI: the nucleopore-promoter interaction of genes in yeast

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7 January 2021

Regulated overproduction of the GAL4 gene product greatly increases expression from galactose-inducible promoters on multi-copy expression vectors in yeast

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7 January 2021

Characterization of the Saccharomyces cerevisiae galactose mutarotase/UDP-galactose 4-epimerase protein, Gal10p.

1 reference

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7 January 2021

Lactose metabolism and cellulase production in Hypocrea jecorina: the gal7 gene, encoding galactose-1-phosphate uridylyltransferase, is essential for growth on galactose but not for cellulase induction

1 reference

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7 January 2021

The galactokinase of Hypocrea jecorina is essential for cellulase induction by lactose but dispensable for growth on d-galactose

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7 January 2021

Contribution of amino acid side chains to sugar binding specificity in a galactokinase, Gal1p, and a transcriptional inducer, Gal3p

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7 January 2021

The Gal3p-Gal80p-Gal4p transcription switch of yeast: Gal3p destabilizes the Gal80p-Gal4p complex in response to galactose and ATP.

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7 January 2021

Intracellular galactose-1-phosphate accumulation leads to environmental stress response in yeast model

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https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

The organization and transcription of the galactose gene cluster of Saccharomyces

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7 January 2021

Analysis of the galactose signal transduction pathway in Saccharomyces cerevisiae: interaction between Gal3p and Gal80p

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7 January 2021

Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins.

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7 January 2021

Nuclear pore association confers optimal expression levels for an inducible yeast gene

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https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

The molecular architecture of galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Structural analysis of the H166G site-directed mutant of galactose-1-phosphate uridylyltransferase complexed with either UDP-glucose or UDP-galactose: detailed description of the nucleotide sugar binding site

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Molecular structure of Saccharomyces cerevisiae Gal1p, a bifunctional galactokinase and transcriptional inducer

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https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Understanding a transcriptional paradigm at the molecular level. The structure of yeast Gal80p

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Functional analysis of disease-causing mutations in human UDP-galactose 4-epimerase

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

The structural and molecular biology of type III galactosemia.

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Kinetic analysis of yeast galactokinase: implications for transcriptional activation of the GAL genes

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Functional analysis of disease‐causing mutations in human galactokinase

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Identification and characterisation of human aldose 1-epimerase

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https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Gal3p and Gal1p interact with the transcriptional repressor Gal80p to form a complex of 1:1 stoichiometry

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7 January 2021

The in vitro effects of galactose and its derivatives on rat brain Mg2+-ATPase activity

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7 January 2021

The acidic activation domains of the GCN4 and GAL4 proteins are not alpha helical but form beta sheets

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https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

mRNA export: an assembly line from genes to nuclear pores

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https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Galactose induction in yeast involves association of Gal80p with Gal1p or Gal3p

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https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Gene regulation by the yeast Ssn6-Tup1 corepressor

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https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Some properties of galactokinase in developing rat liver

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https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Three-Dimensional Structure of Galactose-1-phosphate Uridylyltransferase from Escherichia coli at 1.8 .ANG. Resolution

1 reference

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7 January 2021

The structure of nucleotidylated histidine-166 of galactose-1-phosphate uridylyltransferase provides insight into phosphoryl group transfer

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Molecular evidence for an ancient duplication of the entire yeast genome

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Galactose-dependent reversible interaction of Gal3p with Gal80p in the induction pathway of Gal4p-activated genes of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

A yeast catabolic enzyme controls transcriptional memory

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Gal80 proteins of Kluyveromyces lactis and Saccharomyces cerevisiae are highly conserved but contribute differently to glucose repression of the galactose regulon

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Regulated phosphorylation of the Gal4p inhibitor Gal80p of Kluyveromyces lactis revealed by mutational analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Ssn6-Tup1 requires the ISW2 complex to position nucleosomes in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

Recruitment of the transcriptional machinery through GAL11P: structure and interactions of the GAL4 dimerization domain

1 reference

https://api.crossref.org/works/10.1016%2FS1937-6448%2808%2901003-4

7 January 2021

10.1016/S1937-6448(08)01003-4

Identifiers

DOI

1 reference

19 August 2017

1 reference