(Q37265001)

English

Deletion of Cdc42 enhances ADAM17-mediated vascular endothelial growth factor receptor 2 shedding and impairs vascular endothelial cell survival and vasculogenesis

scientific article published on 26 August 2013

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Deletion of Cdc42 enhances ADAM17-mediated vascular endothelial growth factor receptor 2 shedding and impairs vascular endothelial cell survival and vasculogenesis (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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Yixin Jin

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Yang Liu

2

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19 August 2017

Qiong Lin

3

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Europe PubMed Central

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19 August 2017

Jieli Li

4

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Europe PubMed Central

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19 August 2017

Joseph E Druso

5

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Europe PubMed Central

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19 August 2017

Marc A Antonyak

6

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Europe PubMed Central

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19 August 2017

Cynthia J Meininger

7

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Europe PubMed Central

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19 August 2017

Shenyuan L Zhang

8

1 reference

Europe PubMed Central

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19 August 2017

David E Dostal

9

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19 August 2017

Jun-Lin Guan

10

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19 August 2017

Richard A Cerione

11

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19 August 2017

Xu Peng

12

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19 August 2017

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publication date

26 August 2013

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19 August 2017

Molecular and Cellular Biology

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19 August 2017

33

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19 August 2017

21

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Europe PubMed Central

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19 August 2017

4181-4197

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Cycling around cell-cell adhesion with Rho GTPase regulators

1 reference

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6 September 2017

Cdc42 controls vascular network assembly through protein kinase Cι during embryonic vasculogenesis

1 reference

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6 September 2017

Molecular mechanisms and clinical applications of angiogenesis

1 reference

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6 September 2017

Cdc42 in oncogenic transformation, invasion, and tumorigenesis

1 reference

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6 September 2017

Dynamics of endothelial cell behavior in sprouting angiogenesis

1 reference

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Cdc42 and vesicle trafficking in polarized cells.

1 reference

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6 September 2017

Role of kinase-independent and -dependent functions of FAK in endothelial cell survival and barrier function during embryonic development

1 reference

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Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism

1 reference

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Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth.

1 reference

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Cytoskeleton-membrane interactions in membrane raft structure

1 reference

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Transcriptional control of endothelial cell development.

1 reference

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6 September 2017

The ADAMs: signalling scissors in the tumour microenvironment

1 reference

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6 September 2017

VEGF-A stimulates ADAM17-dependent shedding of VEGFR2 and crosstalk between VEGFR2 and ERK signaling.

1 reference

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6 September 2017

Mammalian Rho GTPases: new insights into their functions from in vivo studies

1 reference

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Integrins in angiogenesis and lymphangiogenesis

1 reference

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Cardiac developmental defects and eccentric right ventricular hypertrophy in cardiomyocyte focal adhesion kinase (FAK) conditional knockout mice

1 reference

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6 September 2017

Vascular remodeling of the mouse yolk sac requires hemodynamic force

1 reference

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6 September 2017

Endothelium-microenvironment interactions in the developing embryo and in the adult

1 reference

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6 September 2017

The shedding activity of ADAM17 is sequestered in lipid rafts

1 reference

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6 September 2017

Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer

1 reference

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6 September 2017

VEGF receptor signalling - in control of vascular function

1 reference

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6 September 2017

Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response

1 reference

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6 September 2017

Endothelial cells and VEGF in vascular development

1 reference

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6 September 2017

Angiogenesis in life, disease and medicine

1 reference

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6 September 2017

FAK-mediated src phosphorylation of endophilin A2 inhibits endocytosis of MT1-MMP and promotes ECM degradation

1 reference

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6 September 2017

Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811890

6 September 2017

ADAMs: key components in EGFR signalling and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811890

6 September 2017

Cdc42: new roads to travel

1 reference

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6 September 2017

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

1 reference

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6 September 2017

Rho GTPases in cell biology

1 reference

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6 September 2017

Signaling pathways in vascular development

1 reference

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6 September 2017

Adhesion events in angiogenesis.

1 reference

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6 September 2017

Conditional vascular cell adhesion molecule 1 deletion in mice: impaired lymphocyte migration to bone marrow

1 reference

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Vascular-specific growth factors and blood vessel formation

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A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

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6 September 2017

Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures

1 reference

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6 September 2017

Inactivation of Cdc42 in embryonic brain results in hydrocephalus with ependymal cell defects in mice

1 reference

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14 September 2017

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14 September 2017

Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability

1 reference

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28 September 2017

A disintegrin and metalloprotease 10 is a novel mediator of vascular endothelial growth factor-induced endothelial cell function in angiogenesis and is associated with atherosclerosis.

1 reference

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26 June 2018

Formation of endothelial lumens requires a coordinated PKCepsilon-, Src-, Pak- and Raf-kinase-dependent signaling cascade downstream of Cdc42 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811890

26 June 2018

Cell interactions in the mouse yolk sac: vasculogenesis and hematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811890

26 June 2018

Signaling vascular morphogenesis and maintenance

1 reference

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1 reference

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3 September 2018

Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3811890

3 September 2018

A signalling cascade involving PKC, Src and Cdc42 regulates podosome assembly in cultured endothelial cells in response to phorbol ester

1 reference

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3 September 2018

Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38.

1 reference

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3 September 2018

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3 September 2018

Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress.

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Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases

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Isolation and characterization of vascular endothelial cells from murine heart and lung

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12 December 2020

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The generation of the endothelial specific cdc42-deficient mice and the effect of cdc42 deletion on the angiogenesis and embryonic development

1 reference

https://pubmed.ncbi.nlm.nih.gov/23979594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Integrins in vascular development

1 reference

https://pubmed.ncbi.nlm.nih.gov/23979594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices

1 reference

https://pubmed.ncbi.nlm.nih.gov/23979594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23979594

12 December 2020

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Cdc42 regulates adherens junction stability and endothelial permeability by inducing alpha-catenin interaction with the vascular endothelial cadherin complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/23979594

12 December 2020

based on heuristic

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Cdc42-driven podosome formation in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23979594

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.00650-13

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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