(Q37271598)

English

Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor

scientific article published on April 2009

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Mark R Burns

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Gerard F Graminski

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Reitha S Weeks

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Yan Chen

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Thomas G O'Brien

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

0 references

publication date

1 April 2009

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

52

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1983-1993

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial

1 reference

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Cell penetrating peptides: intracellular pathways and pharmaceutical perspectives

1 reference

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Cationic liposomes as non-viral carriers of gene medicines: resolved issues, open questions, and future promises

1 reference

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Break on through to the other side-biophysics and cell biology shed light on cell-penetrating peptides

1 reference

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Lipid membrane-induced optimization for ligand-receptor docking: recent tools and insights for the "membrane catalysis" model.

1 reference

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Lysine-spermine conjugates: hydrophobic polyamine amides as potent lipopolysaccharide sequestrants

1 reference

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Palmitoylation of intracellular signaling proteins: regulation and function

1 reference

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1 reference

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Glypican-1 is a vehicle for polyamine uptake in mammalian cells: a pivital role for nitrosothiol-derived nitric oxide

1 reference

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6 September 2017

New insights into the mechanisms of protein palmitoylation.

1 reference

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6 September 2017

Guanidinium rich peptide transporters and drug delivery

1 reference

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Arginine-rich molecular transporters for drug delivery: role of backbone spacing in cellular uptake

1 reference

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N-terminal fatty acid substitution increases the leishmanicidal activity of CA(1-7)M(2-9), a cecropin-melittin hybrid peptide

1 reference

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6 September 2017

Probing the mechanism of transport and compartmentalisation of polyamines in mammalian cells.

1 reference

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6 September 2017

N-Acylated and D enantiomer derivatives of a nonamer core peptide of lactoferricin B showing improved antimicrobial activity

1 reference

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6 September 2017

Chemical highlights of polyamine transport

1 reference

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6 September 2017

Identification of a gene for a polyamine transport protein in yeast

1 reference

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6 September 2017

Physical modulation of intracellular signaling processes by locational regulation

1 reference

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6 September 2017

The 1.8-A X-ray structure of the Escherichia coli PotD protein complexed with spermidine and the mechanism of polyamine binding.

1 reference

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6 September 2017

Heparan sulphate/heparin glycosaminoglycans with strong affinity for the growth-promoter spermine have high antiproliferative activity

1 reference

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6 September 2017

Crystal structure of PotD, the primary receptor of the polyamine transport system in Escherichia coli

1 reference

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6 September 2017

Squalamine: an aminosterol antibiotic from the shark

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6 September 2017

Internal lysine palmitoylation in adenylate cyclase toxin from Bordetella pertussis

1 reference

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6 September 2017

Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase.

1 reference

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6 September 2017

Membrane lipid phase as catalyst for peptide-receptor interactions

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Cellular uptake of the tat protein from human immunodeficiency virus

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6 September 2017

Polyamine transport in mammalian cells

1 reference

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6 September 2017

Polyamines in rapid growth and cancer

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Cationic liposome systems in gene therapy.

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Persulfated molecular umbrellas as anti-HIV and anti-HSV agents

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14 September 2017

Molecular requirements for targeting the polyamine transport system. Synthesis and biological evaluation of polyamine-anthracene conjugates

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14 September 2017

Polyamines in mammalian tumors. Part I.

1 reference

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14 September 2017

Polyamines in Mammalian Tumors Part ii

1 reference

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14 September 2017

Putrescine transport is greatly increased in human fibroblasts initiated to proliferate

1 reference

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14 September 2017

Proteoglycan involvement in polyamine uptake.

1 reference

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28 September 2017

Intercellular trafficking and protein delivery by a herpesvirus structural protein

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Comparison of treatment modalities for squamous cell carcinoma

1 reference

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28 September 2017

Polyamine transport in mammalian cells. An update

1 reference

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26 June 2018

Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin.

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26 June 2018

Selective disruption of early/recycling endosomes: release of disulfide-linked cargo mediated by a N-alkyl-3beta-cholesterylamine-capped peptide

1 reference

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3 September 2018

Single chain fragment anti-heparan sulfate antibody targets the polyamine transport system and attenuates polyamine-dependent cell proliferation.

1 reference

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HIV-Tat protein transduction domain specifically attenuates growth of polyamine deprived tumor cells.

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1 reference

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A fluorescent probe of polyamine transport accumulates into intracellular acidic vesicles via a two-step mechanism

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3 September 2018

Xylylated dimers of putrescine and polyamines: influence of the polyamine backbone on spermidine transport inhibition

1 reference

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1 reference

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1 reference

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3 September 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714422

3 September 2018

Amino acid/spermine conjugates: polyamine amides as potent spermidine uptake inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714422

3 September 2018

Ion conductors derived from cholic acid and spermine: importance of facial hydrophilicity on NA(+) transport and membrane selectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714422

3 September 2018

QSAR analysis of polyamine transport inhibitors in L1210 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714422

3 September 2018

Trojan peptides: the penetratin system for intracellular delivery

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Nonmelanoma skin cancer in the United States: incidence.

1 reference

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3 September 2018

Polyamines and prostatic carcinoma: clinical and therapeutic implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2714422

3 September 2018

Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone).

1 reference

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3 September 2018

Labeled putrescine as a probe in brain tumors.

1 reference

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3 September 2018

Biological significance of circulating polyamines in oncology

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyamine profiles in tumor, normal tissue of the homologous breast, blood, and urine of breast cancer sufferers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benefits of complete polyamine deprivation in hormone responsive and hormone resistant MCF-7 human breast adenocarcinoma in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spermidine requirement for cell proliferation in eukaryotic cells: structural specificity and quantitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyamine deprivation: a new tool in cancer treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Solid-phase extraction and determination of dansyl derivatives of unconjugated and acetylated polyamines by reversed-phase liquid chromatography: improved separation systems for polyamines in cerebrospinal fluid, urine and tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous and exogenous polyamines in support of tumor growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiproliferative properties of polyamine analogues: a structure-activity study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for highly cooperative binding between molecular umbrella-spermine conjugates and DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of octapeptin-membrane interactions using spin-labeled octapeptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of structure-activity relationships between spermidine and spermine analogue antineoplastics

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative molecular field analysis-based predictive model of structure-function relationships of polyamine transport inhibitors in L1210 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-terminal modifications of Polymyxin B nonapeptide and their effect on antibacterial activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2,2'-Dithiobis(N-ethyl-spermine-5-carboxamide) is a high affinity, membrane-impermeant antagonist of the mammalian polyamine transport system

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial polyamine uptake: selective stimulation by L-arginine deprivation or polyamine depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/19281226

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM801580W

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

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