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Probing the role of the cation-pi interaction in the binding sites of GPCRs using unnatural amino acids.
scholarly article
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
title
Probing the role of the cation-pi interaction in the binding sites of GPCRs using unnatural amino acids
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
main subject
G protein-coupled receptor
0 references
author
Henry Lester
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
author name string
Michael M Torrice
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Kiowa S Bower
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
Dennis A Dougherty
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
language of work or name
English
0 references
publication date
6 July 2009
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
volume
106
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
issue
29
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
page(s)
11919-11924
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
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Nicotine binding to brain receptors requires a strong cation-pi interaction
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PubMed Central
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The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist
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6 September 2017
Unnatural amino acid replacement in a yeast G protein-coupled receptor in its native environment
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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6 September 2017
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Structural diversity of G protein-coupled receptors and significance for drug discovery
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6 September 2017
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor
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6 September 2017
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function
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6 September 2017
Crystal structure of the human beta2 adrenergic G-protein-coupled receptor
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6 September 2017
Improved amber and opal suppressor tRNAs for incorporation of unnatural amino acids in vivo. Part 1: minimizing misacylation
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6 September 2017
In vivo incorporation of multiple unnatural amino acids through nonsense and frameshift suppression.
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6 September 2017
Molecular mechanism of 7TM receptor activation--a global toggle switch model
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6 September 2017
Gating of GIRK channels: details of an intricate, membrane-delimited signaling complex
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6 September 2017
Mapping the Gbetagamma-binding sites in GIRK1 and GIRK2 subunits of the G protein-activated K+ channel
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6 September 2017
Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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6 September 2017
Drug design strategies for targeting G-protein-coupled receptors
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6 September 2017
The druggable genome
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6 September 2017
Cation-pi interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors: the anomalous binding properties of nicotine
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6 September 2017
Cation-pi interactions in ligand recognition and catalysis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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6 September 2017
Seven-transmembrane receptors: crystals clarify
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6 September 2017
The Cationminus signpi Interaction
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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6 September 2017
The binding site of aminergic G protein-coupled receptors: the transmembrane segments and second extracellular loop
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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6 September 2017
Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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6 September 2017
G-protein mediated gating of inward-rectifier K+ channels
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reference URL
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6 September 2017
Crystal structure of rhodopsin: A G protein-coupled receptor
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6 September 2017
Cation-pi interactions in structural biology
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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6 September 2017
From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor
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PubMed Central
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6 September 2017
RGS proteins reconstitute the rapid gating kinetics of gbetagamma-activated inwardly rectifying K+ channels
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PubMed Central
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6 September 2017
Probing the structure and function of the tachykinin neurokinin-2 receptor through biosynthetic incorporation of fluorescent amino acids at specific sites
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6 September 2017
Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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6 September 2017
Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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6 September 2017
Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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14 September 2017
Beta2 adrenergic receptor activation. Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch
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PubMed Central
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28 September 2017
Is there a 'lock' for all agonist 'keys' in 7TM receptors?
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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28 September 2017
Three-dimensional models of neurotransmitter G-binding protein-coupled receptors
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28 September 2017
Hydrophobic Residues of the D2 Dopamine Receptor Are Important for Binding and Signal Transduction
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28 September 2017
Gbetagamma-dependent and Gbetagamma-independent basal activity of G protein-activated K+ channels.
1 reference
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26 June 2018
Construction of a sequence motif characteristic of aminergic G protein-coupled receptors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
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26 June 2018
The functional topography of transmembrane domain 3 of the M1 muscarinic acetylcholine receptor, revealed by scanning mutagenesis.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
retrieved
26 June 2018
In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2715518
retrieved
26 June 2018
Specific tryptophan UV-absorbance changes are probes of the transition of rhodopsin to its active state
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19581583
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
G beta gamma binds directly to the G protein-gated K+ channel, IKACh
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/19581583
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.0903260106
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
ADS bibcode
2009PNAS..10611919T
0 references
PMCID
2715518
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
PubMed ID
19581583
1 reference
stated in
Europe PubMed Central
PMCID
2715518
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19581583%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 February 2020
ResearchGate publication ID
26651393
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